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Two groups of volunteers having no eye disease were examined electro-oculo graphically twice at ten minute intervals. One group smoked in the break, one didn't. In the non-smoking group there are a number of significant correlations between the tested parameters in the dark-period and in the light-period, which could not be found to the same degree in the smoking group. The fact that there were differences between the two groups-even though not interpretable systematicaIly-suggests, that smoking influences physiological processes in the EOG. In the second period of the test, a parallelism in the course of EOG and EEG was observed, the EEG-changes, however, are interpreted more psychologically than pharmacologicaIly. REFERENCES HAASE, E. & MUELLER, W. Meßbare Beeinflussung des EOG durch Zigarettenrauchen1 Klin. Mbl. Augenhk. Bd. 158:677 (1971). HAGER, H. Thrombangiitis obliterans und Auge. Klin. Mbl. Augenhk. Bd. 114:238 (1949). HAUSER, H., SCHWARZE, B.E., ROTH, G. & BICKFORD, R.G. Electroencephalographic changes related to smoking. EEG clin. Neurophysiol. Vol. 10:576P (1958). HEIMBÖCK. Wien. klin. Wschr. Bd. 73:529 (1961). HOLLWICH, F., JÜNEMANN, G. & DAMASKE, E. Auge. In: Nikotin. Edited by Schievelbein. H. Georg Thieme Verlag, Stuttgart (1968). HOMER, L.D. & KOLDER, H. Mathematical model of oscillations in human corneo-retinal potential. Pflügers Arch. ges. Physiol. 287 :197 (1966). KOLDER H. Spontane und experimentelle Änderungen des Bestandpotentials des menschlichen Auges. P{lügerrs Arch. ges. Physiol. 268:258 (1959). KOLDER, H.E. & HOCHGESAND, P. Empirical Model of Electro-Oculogram. Doc. Ophtha!. (1972) in press.
Professor GOSTA KARPE GOSTA KARPE was born in Vadstena, Sweden, 1908. His medical education started in 1927 at the Karolinska Institute in Stockholm During his study he worked parttime in the department of physiology. KARPE served as a resident in the ophthalmological department of Serafiner lasarettet from 1937 till 1941. That year, the university eye clinic was transferred to the newly built Karolinska Sjukhuset, where KARPE became assistant-head of the out-patient department, and lecturer in ophthalmology. In 1949 he was appoin ted professor in ophthalmology at the Karolinska Institute and head of the department of ophthalmology at Karolinska Sjukhuset. KARPE received his doctor degree in 1945 upon completion of his thesis: 'The basis of clinical electroretinography'. This original work opened up a completely new field of clinical investigation. Soon Swedish and foreign pupils flocked into his department to study his new method, a technique at present accepted as an indispensable tool in ophthalmic practice. Since 1945 his work as well as that of his pupils have been devoted mainly to this field of research.
Strychnine and picrotoxin were tested as possible antagonists of two puta tive inhibitory transmitters in the retina: taurine and GABA, Strychnine was shown to antagonize the depressive action of taurine on the ERG b-wave, but it did not affect the depressive action of GABA. Conversely, picrotoxin had no effect on the depressive action of taurine on the ERG b-wave, but it antagonizes to some extent the depressive effect of GABA. These data, as well as those obtained through recording tectal evoked responses, lead to the conclusion that taurine and GABA do not act in the same way in retinal inhibitory synaptic transmission. REFERENCES CURTIS, D.R., AW. DUGGAN & G.A.R. JOflNSTON. Glycine, strychnine, picro toxine and spinal inhibition. Brain Res. 14, 759-762 (1969). CURTIS, D.R., L. HOSLI & G. AR. JOHNSTON. A pharmacological study of the depression of spinal neurones by glycine and related aminoacids. Exp. Brain Res. 6, 1-18 (1968 a). CURTIS, D.R., L. HOSLI, G.A.R. JOHNSTON & LH. JOHNSTON. The hyperpolariza tion of spinal motoneurones by glycine and related aminoacids. Exp. Brain Res. 5, 235-258 (1968 b). CURTIS, D.R. & A.K. TEBECIS. Bicuculline and thalamic inhibition. Exp. Brain Res. 16,210-218 (1972). DA VIDSON, N. & H. REISINE. Presynaptic inhibition in cuneate blocked by GABA antagonists. Nature New Biology 234,223-224 (1971).
Since its inception, the International Research Group on Colour Vision Deficiencies (IRGCVD) has followed the policy that the Symposium Pro ceedings should be as close as possible to a complete record of the scientific content of the meeting. This policy has the advantage of providing an accurate picture of the current state of the art in research on color vision deficiencies, but it also has the disadvantage that papers typically span a wide range of quality. In this volume, however, we have instituted a system of peer review in an effort to enhance scientific quality as much as possible while continuing our past policy of publishing all submitted manuscripts. In addition to being edited for English composition and grammar, each of the papers included here has been carefully reviewed by an IRGCVD member selected for his or her expertise in the specific topic of the paper. Reviewers were instructed to include in their comments suggestions for improvement rather than recom or rejection. In our opinion, this review process mendations for publication has resulted in substantial improvement of many of the articles and has enhanced the value of the publication. We are pleased to acknowledge the efforts of our reviewers and offer them our sincere thanks for their important contributions to Colour Vision Deficiencies X. The Editors B. Drum, J. D. Moreland & A. Serra (eds. ), Colour Vision Deficiencies X, p. xiii.
First multi-year cumulation covers six years: 1965-70.
XIVth ISCERG Symposium, Louisville, Kentucky, USA, 10-14 May, 1976
Proceedings of the 19th ISCEV Symposium, Horgen-Zürich, Switzerland, June 1-5, 1981
The eleventh Symposium of the International Research Group on Colour Vision Deficiencies (IRGCVD) was held 20-23 June 1991 in Sydney, Aus tralia, ably hosted by local organizer Stephen Dain. A total of 35 talks and 10 posters were presented. Papers based on 37 of these presentations are included here, in Colour Vision Deficiencies XI. The scientific program featured sessions on three special topics, with each topic highlighted by an invited speaker. The opening session on the Genetics of congenital colour vision deficiencies began with a superb invited lecture by Charles Weitz about his pioneering work on the molecular genetics of tritanopia. The session on the second special topic, Spatial aspects of colour vision, began with the launching of a new IRGCVD tradition, as 1991 Verriest Memorial Award recipient Harry Sperling presented the first Ver riest Memorial Lecture on his recent studies of spatial discrimination of heterochromatic stimuli. Dr. Sperling reported new evidence that certain asymmetries in red-green opponent colour vision can be explained by the spatial organization of colour-opponent retinal neurons. In the third special session, on Occupational aspects of colour vision, Barry Cole took the audi ence on a fascinating tour of the historical development of colour vision standards in his invited lecture entitled 'Does defective colour vision really matter?'. In addition to the three special topics, many interesting presentations were given in topical sessions on Variations in normal colour vision, Acquired colour vision deficiencies and Colour vision tests and testing methods.
The 13th biennial Symposium of the International Research Group on Colour Vision Deficiencies was held from 27 July to 30 July, 1995, in the splendidjin de siecle Theatre Saint Louis, in Pau, France. A total of 80 papers and posters were presented during the four days, of which 56 have been selected for inclusion in this volume. Each has been reviewed by two of the Editors. Additionally, in numerous cases in which specialized knowledge was called for the Editors asked for external help; their assistance is acknowledged below. While Pau now exists largely on agriculture and, more recently, oil extraction and refining, a century ago it was a winter resort that rivalled Cannes and Nice; indeed, Baedeker judged the air of Pau to be preferable for those of a nervous disposition. Pau and the surrounding Beam district are rich in history and have close ties to the Basque region, both of which were exploited brilliantly by the local organizers, Doctors Jean and Veronique Lied, to introduce the partici pants to the gastronomy and traditions of the region. The Committee of the IRGCVD owe a great debt of gratitude to the external reviewers, Oscar Estevez, Karl Gegenfurtner, Gunilla Haegerstrom-Portnoy, RL. Hilz, John Krauskopf, Anne Kurtenbach, Barry B. Lee, Adam Reeves, Marilyn Schneck, L.T. Sharpe, Eugene Switkes, Wayne Verdon, and B.A.
From the 98 presentations of the XIIth Symposium on Colour Vision Deficiencies, 61 were selected after peer review and revision by the authors. In addition to these contributions this volume contains a cumulative index to all authors in the IRGCVD proceedings since the first one in 1968, including the present volume. The contents include contributions on basic questions of anatomical and electrophysiological organisation of the neural pathways underlying colour vision; and on ways in which disturbances of these pathways can produce acquired colour vision deficiencies. Further contributions deal with genetics and congenital red--green colour deficiencies and colour vision testing. The resulting publication contains much of interest to basic vision scientists as well as to specialists in colour vision deficiencies.