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Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical response to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control and the effects of stimulants on these systems. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those pursuing development of new drugs to treat ADHD.
In this volume, leading researchers bring together current work on time perception and time-based prospective memory in order to understand how people time their intentions. This is the first account of many important topics concerning the timing of behavior, offered by scientists of diverse fields who in the past have exhibited an attitude of mutual 'benign neglect'. An explication of the rules which govern timing the future are of fundamental interest to anyone who wishes to explore the potential of human experience.Prospective memory — especially time-based — is a relatively unexplored way to study memory and few studies have been devoted to its neurobiological foundations. This volume aims to fill this void and will boost further interest in the field, while stimulating interdisciplinary research.
This book constitutes the refereed post-conference proceedings of two conferences: The 7th EAI International Conference on ArtsIT, Interactivity and Game Creation (ArtsIT 2018), and the 3rd EAI International Conference on Design, Learning, and Innovation (DLI 2018). Both conferences were hosed in Braga, Portugal, and took place October 24-26, 2018. The 51 revised full papers presented were carefully selected from 106 submissions. ArtsIT , Interactivity and Game Creation is meant to be a place where people in arts, with a keen interest in modern IT technologies, meet with people in IT, having strong ties to art in their works. The event also reflects the advances seen in the open related topics Interactivity (Interaction Design, Virtual Reality, Augmented Reality, Robotics) and Game Creation (Gamification, Leisure Gaming, GamePlay). ArtsIT has been successfully co-located with DLI as the design, learning and innovation frame the world of IT, opening doors into an increasingly playful worlds. So the DLI conference is driven by the belief that tools, techniques and environments can spark and nature a passion for learning, transformation domains such as education, rehabilitation/therapy, work places and cultural institutions.
Oxford Textbook of Attention Deficit Hyperactivity Disorder is an authoritative, multi-disciplinary text covering the diagnosis, assessment and management of patients with ADHD.
This volume provides a comprehensive review of historical and current research on the function of the frontal lobes and frontal systems of the brain. The content spans frontal lobe functions from birth to old age, from biochemistry and anatomy to rehabilitation, and from normal to disrupted function. The book is intended to be a standard reference work on the frontal lobes for researchers, clinicians, and students in the field of neurology, neuroscience, psychiatry, psychology, and health care.
This special issue ponders a detailed and contemporary analysis of the theoretical underpinnings of short-term and working memory. Articles focus on short-term memory for phonological, semantic, and spatial material, on executive function and on short-term forgetting. The empirical perspectives include the neuroimaging of short-term memory, short-term memory development and the neuropsychology and neurobiology of memory, in addition to laboratory-based experimental studies. Together, these articles identify significant current models and approaches to short-term and working memory, providing a broad set of perspectives which illustrate the wide impact of working memory on the understanding of human cognition.
'Working Memory, Thought, and Action' is the magnum opus of one of the most influential cognitive psychologists of the past 50 years. This new volume on the model he created (with Graham Hitch) discusses the developments that have occurred within the model in the past twenty years, and places it within a broader context. Working memory is a temporary storage system that underpins our capacity for coherent thought. Some 30 years ago, Baddeley and Hitch proposed a way of thinking about working memory that has proved to be both valuable and influential in its application to practical problems. This book updates the theory, discussing both the evidence in its favour, and alternative approaches. In addition, it discusses the implications of the model for understanding social and emotional behaviour, concluding with an attempt to place working memory in a broader biological and philosophical context. Inside are chapters on the phonological loop, the visuo-spatial sketchpad, the central executive and the episodic buffer. There are also chapters on the relevance to working memory of studies of the recency effect, of work based on individual differences, and of neuroimaging research. The broader implications of the concept of working memory are discussed in the chapters on social psychology, anxiety, depression, consciousness and on the control of action. Finally, Baddeley discusses the relevance of a concept of working memory to the classic problems of consciousness and free will. This new volume from one of the pioneers in memory research will doubtless emulate the success of its predecessor, and be a major publication within the psychological literature.
Covering basic theory, new research, and intersections with adjacent fields, this is the first comprehensive reference work on cognitive control – our ability to use internal goals to guide thought and behavior. Draws together expert perspectives from a range of disciplines, including cognitive psychology, neuropsychology, neuroscience, cognitive science, and neurology Covers behavioral phenomena of cognitive control, neuroanatomical and computational models of frontal lobe function, and the interface between cognitive control and other mental processes Explores the ways in which cognitive control research can inform and enhance our understanding of brain development and neurological and psychiatric conditions
Renowned authority Russell Barkley provides a radical shift of perspective on ADHD. He argues that the disorder is not at root attentional, but rather a developmental problem of self-control. Offering new directions for thinking about and working with those with ADHD, this model has far-reaching implications for clinical practice.