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The Santa Fe Trail was a 19th-century transportation route through central North America that connected Franklin, Missouri with Santa Fe, New Mexico, pioneered in 1821 by William Becknell, What did James Little see in mid-century on the Santa Fe Trail? Among other things: "Caravans of Prairie Schooners, Forty Wagons, Five-hundred Oxen, Millions of Buffaloes, Thousands of Wild Horses, Antelopes. Big Grey Wolves and Cayotes, Prairie Dog Towns and Jack Rabbits. Rattle Snakes, Lizards and Centepedes, Savage Indians and Mexicans, Strange Sights Crossing the Desert..." This lively and simple account of Little's time in a world now gone is a treasure of 19th century pioneer biographies. For the first time, this long out-of-print volume is available as an affordable, well-formatted book for e-readers and smartphones. Be sure to LOOK INSIDE by clicking the cover above or download a sample.
A biography and a complete bibliography of New Mexico's leading independent historian.
Proceedings of the Thirteenth International Workshop on Maximum Entropy and Bayesian Methods
James Josiah Webb left Independence, Missouri, in the summer of 1844 and headed down the Santa Fe Trail with goods bought in St. Louis. Although his first venture as a trader was a failure, he eventually made a fortune as a merchant in Santa Fe. Webb recorded his youthful experiences in 1888, and Ralph P. Bieber, a respected scholar and researcher on western expansion, edited and annotated his journal for publication more than forty years later. Long out of print, Adventures in the Santa Fe Trade is an entertaining and important source of first-hand information about the Santa Fe Trail and trade; trappers, Mexicans, and Indian tribes of the Old Southwest; and the impact of the Mexican War on southwestern trade.
Two decades have passed since the mechanisms of protein synthesis became well enough understood to permit the genetic modification oforganisms. An impressive amount of new knowledge has emerged from the new technology, but much ofthe promise of20years ago has notyet been fulfilled. In biotechnology, efforts to increase the yields of commercially valuable metabolites have been less successful than ex pected, and when they have succeeded it has often been as much from selective breeding as from new methods. The cell is more complicated than what is presented in the classical teaching of biochemistry, it contains more structure than was dreamed of 20 years ago, and the behaviour ofany systemofenzymes is more elaborate than can be explained in terms ofa single supposedly rate-limiting enzyme. Even if classical enzymology and meta bolism may have seemed rather unfashionable during the rise ofmolecular biology, they remain central to any modification ofthe metabolic behaviour oforganisms. As such modification is essential in much ofbiotechnology and drug development, bio technologists can only ignore these topics at their peril.
Recently identified as a killer, tobacco has been the focus of health warnings, lawsuits, and political controversy. Yet many Native Americans continue to view tobacco-when used properly-as a life-affirming and sacramental substance that plays a significant role in Native creation myths and religious ceremonies. This definitive work presents the origins, history, and contemporary use (and misuse) of tobacco by Native Americans. It describes wild and domesticated tobacco species and how their cultivation and use may have led to the domestication of corn, potatoes, beans, and other food plants. It also analyzes many North American Indian practices and beliefs, including the concept that Tobacco is so powerful and sacred that the spirits themselves are addicted to it. The book presents medical data revealing the increasing rates of commercial tobacco use by Native youth and the rising rates of death among Native American elders from lung cancer, heart disease, and other tobacco-related illnesses. Finally, this volume argues for the preservation of traditional tobacco use in a limited, sacramental manner while criticizing the use of commercial tobacco. Contributors are: Mary J. Adair, Karen R. Adams, Carol B. Brandt, Linda Scott Cummings, Glenna Dean, Patricia Diaz-Romo, Jannifer W. Gish, Julia E. Hammett, Robert F. Hill, Richard G. Holloway, Christina M. Pego, Samuel Salinas Alvarez, Lawrence A Shorty, Glenn W. Solomon, Mollie Toll, Suzanne E. Victoria, Alexander von Garnet, Jonathan M. Samet, and Gail E. Wagner.