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This up-to-the-minute and comprehensive resource lucidly covers gene therapy for lung diseases from existing technologies delivering foreign DNA to the lungs via the airways or circulation to promising new approaches for the further development of safe and efficient gene delivery systems.
One of the deadliest firefights in the history of the FBI occurred in 1986 in Miami, Florida. Lasting more than four minutes, the fight claimed the lives of two FBI agents and two extremely violent master criminals and severely injured five other FBI agents. On the 10th anniversary of the shootout, W. French Anderson, M.D., released his seminal study, "Forensic Analysis of the April 11, 1986, FBI Firefight". Anderson's report - the most well-researched, well-documented account of a gunfight in modern history - was available only to law enforcement personnel . . . until now. On the 20th anniversary of the firefight that revolutionized the way law enforcement agencies around the nation arm and train their agents, Dr. Anderson makes "Forensic Analysis" available to the public for the first time.
We've all heard that a father's involvement enriches the lives of children. But how much have we heard about how having a child affects a father's life? As Peter Gray and Kermyt Anderson reveal, fatherhood actually alters a man's sexuality, rewires his brain, and changes his hormonal profile. His very health may suffer—in the short run—and improve in the long. These are just a few aspects of the scientific side of fatherhood explored in this book, which deciphers the findings of myriad studies and makes them accessible to the interested general reader. Since the mid-1990s Anderson and Gray, themselves fathers of young children, have been studying paternal behavior in places as diverse as Boston, Albuquerque, Cape Town, Kenya, and Jamaica. Their work combines the insights of evolutionary and comparative biology, cross-cultural analysis, and neural physiology to deepen and expand our understanding of fatherhood—from the intense involvement in childcare seen in male hunter-gatherers, to the prodigality of a Genghis Khan leaving millions of descendants, to the anonymous sperm donor in a fertility clinic. Looking at every kind of fatherhood—being a father in and out of marriage, fathering from a distance, stepfathering, and parenting by gay males—this book presents a uniquely detailed picture of how being a parent fits with men's broader social and work lives, how fatherhood evolved, and how it differs across cultures and through time.
"Issues in bioethics, medicine, and healthcare continue to plague us - as patients as consumers, as citizens. Here, under one cover, are thirty of the most current and perceptive articles, culled from key medical, ethical, philosophical, legal and theological journals. Dr. Shannon once again offers - to healthcare professionals and students alike - access to this decade's core bioethics questions, a spectrum of viewpoints, and a wealth of insight."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
In a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology’s progress from gene to genome in one hundred years, The Century of the Gene also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene—word and object—as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.
Lewis pens the first book to tell the fascinating story of gene therapy: how it works, the science behind it, how patients (mostly children) have been helped and harmed, and how scientists learned from each trial to get one step closer to the promise of a cure.
The French Revolution invented the notion of the citizen, but it also invented the noncitizen—the person whose rights were nonexistent. The South American outpost of Guiana became a depository for these outcasts of the new French citizenry, and an experimental space for the exercise of new kinds of power and violence against marginal groups.
The official behind-the-scenes companion to The French Dispatch and the latest volume in the bestselling Wes Anderson Collection series The French Dispatch—the tenth feature film from writer-director Wes Anderson—is a love letter to journalists set at the titular American newspaper in the fictional 20th-century French city of Ennui-sur-Blasé. The film stars a number of Anderson's frequent collaborators, including Bill Murray as the newspaper's editor in chief; Owen Wilson, Tilda Swinton, and Frances McDormand, as well as new players Jeffrey Wright, Benicio del Toro, Elisabeth Moss, and Timothée Chalamet, who bring to life a collection of stories published in The French Dispatch magazine. In this latest one-volume entry in The Wes Anderson Collection series—the only book to take readers behind the scenes of The French Dispatch—everything that goes into bringing Anderson's trademark style, meticulous compositions, and exacting production design to the screen is revealed in detail. Written by film and television critic and New York Times bestselling author Matt Zoller Seitz, The Wes Anderson Collection: The French Dispatch presents the complete story behind the film’s conception, anecdotes about the making of the film, and behind-the-scenes photos, production materials, and artwork.
What are the imagined communities that compel men to kill or to die for an idea of a nation? This notion of nationhood had its origins in the founding of the Americas, but was then adopted and transformed by populist movements in nineteenth-century Europe. It became the rallying cry for anti-Imperialism as well as the abiding explanation for colonialism. In this scintillating, groundbreaking work of intellectual history Anderson explores how ideas are formed and reformulated at every level, from high politics to popular culture, and the way that they can make people do extraordinary things. In the twenty-first century, these debates on the nature of the nation state are even more urgent. As new nations rise, vying for influence, and old empires decline, we must understand who we are as a community in the face of history, and change.