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A practical and succinct guide to neurophysiological monitoring for safer brain tumor surgery The surgical treatment of infiltrating brain tumors is an extremely challenging and often highly rewarding facet of neurosurgery. The decision-making process involves deeply human interconnections with patients and relatives, cutting-edge neuroscience, and fascinating technology. Video Atlas of Neurophysiological Monitoring in Surgery of Infiltrating Brain Tumors by renowned oncological neurosurgeon Michael Sabel and esteemed contributors demonstrates the practical applications of neurophysiological monitoring to achieve safe removal of infiltrating brain tumors in asleep and awake settings. Organized in three primary parts, the book starts with an introduction including a discussion of the impact and challenges posed by infiltrating gliomas and cerebral metastases and the philosophy behind supramarginal resection. The second part covers critical theoretical components including relevant anatomy, nervous system electricity and fields, transcranial monitoring methods and principles, and direct cortical and subcortical mapping including awake brain surgery. The final part provides insightful, practical guidance on decision making, monitoring set-up, planning of surgical cases, and a summary of accompanying videos. Key Highlights Discussion of impacted anatomy, physiology of the neural pathways monitored in brain tumor surgery, and key neurophysiological techniques for monitoring and testing during resection Instructive illustrations coupled with concise explanations enhance knowledge and facilitate understanding of techniques Fifteen videos covering real-life intraoperative cases provide in-depth insights on applying IONM principles to infiltrating brain tumors This is an essential resource for any neurosurgeon involved or interested in brain tumor surgery, from residents and fellows to board-certified neurosurgeons not yet trained in this field.
From reviews of previous volumes: Ranks with the very best previous attempts at codifying neurosurgical operations. The attention to detail is excellent... -The New England Journal of Medicine A valuable addition to any library...I would recommend it to all neurosurgeons with an interest in cerebrovascular disease...The operative photographs are of extremely high quality.-Chicago Medicine The final volume in the acclaimed series provides coverage of the anatomy, surgical approaches, and techniques involved in performing cerebral revascularization. Filled with over 2,000 vibrant images, it provides the visual instruction neurosurgeons need. Highlights include: A complete section detailing intracranial vasculature and anatomy of the spinal cord A case material section featuring a rich diversity of clinical situations to illustrate a variety of microsurgical techniques Thorough coverage of bypasses, reconstructions, and the use of endarterectomy to achieve revascularization Presentation of both surgical and endovascular techniques for re-establishing blood flow through the carotid and cerebral arteries Information on tumors of the spinal cord and spinal vascular malformations, particularly cavernous and arteriovenous malformations
The definitive textbook on state-of-the-art fluorescence-guided neurosurgery Advances in fluorescence-guided surgery (FGS) have resulted in a paradigm shift in neurosurgical approaches to neuro-oncological and cerebrovascular pathologies. Edited by two of the foremost authorities on the topic, Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications encompasses the depth and breadth of this groundbreaking, still nascent technology. The book reflects significant contributions made by world renowned neurosurgeons Constantinos Hadjipanayis, Walter Stummer, and esteemed contributors on the growing uses of 5-aminolevulinic acid (5-ALA) and other FGS agents. The European Medicine Agency approved 5-ALA in 2007, heralding the birth of FGS globally. In 2017, the U.S. Food and Drug Administration approved 5-ALA (Gleolan) as an imaging agent to facilitate realtime detection and visualization of malignant tissue during glioma surgery. In the two decades since Dr. Stummer's initial description of 5-ALA FGS in a human patient, major strides have been made in its practical applications, leading to improved resection outcomes. As FGS is increasingly incorporated into neurosurgical practice, it holds promise for future innovations. Generously-illustrated and enhanced with online videos, this textbook is the definitive resource on the subject. Key Features The improved efficacy of 5-ALA for resecting high- and low-grade gliomas, recurrences, meningiomas, brain metastases, spinal cord tumors, pediatric brain tumors, and other adult tumors The future of fluorescence, including potentially powerful new fluorophores molecularly targeted specifically to tumors The use of the fluorescent agent indocyanine green (ICG) for brain tumors, cerebral aneurysms, AVMs, and cerebral vascularization Special topics such as fluorescein, illuminating tumor paint, confocal microscopy, Raman spectroscopy, and integrating FGS with intraoperative imaging and brain mapping This single accessible reference presents the current state-of-the-art on this emerging, exciting surgical technology. As such, it is a must-have for neurosurgical residents, fellows, and practicing neurosurgeons.
The one-stop resource on deep brain stimulation for functional neurosurgeons! Deep brain stimulation (DBS) is used to modulate dysfunctional circuits in the brain with stimulation pulses applied to specific target areas of the brain. Globally, DBS procedures have been most commonly performed for Parkinson's disease and essential tremor, but there are now new and growing research efforts studying DBS for psychiatric disorders and epilepsy. Deep Brain Stimulation: Techniques and Practices written by the Society for Innovative Neuroscience in Neurosurgery along with Dr. William S. Anderson and distinguished experts presents the latest DBS approaches. The book begins with a history of DBS, general frame-based techniques, patient selection primarily for movement disorders, multidisciplinary collaboration, and ethical considerations. Subsequent chapters detail diverse technologies and disease-specific treatment for Parkinson's disease, essential tremor, dystonia, OCD, epilepsy, major depression, Tourette syndrome, emerging psychiatric indications, and pediatric applications. Key highlights Lead placement techniques utilizing currently available customized platforms and robotics Microelectrode recording and image-based direct targeting with MRI and CT to enhance lead placement Lesioning methods including radiofrequency, and MR-guided focused ultrasound Discussion of recent innovations in tractography to delineate white matter tracts in the brain and closed loop stimulation DBS has helped thousands of patients with intractable conditions, allowing for a programmable therapy with durable treatment effect. This remarkable guide provides the essentials for functional neurosurgeons to pursue intraoperative research opportunities in this growing subspecialty and incorporate DBS into clinical practice.
HIGHLY COMMENDED by the BMA Medical Book Awards for Neurology! Neurosonology and Neuroimaging of Stroke: A Comprehensive Reference Neurosonology is a first-line modality in the diagnosis and management of cerebrovascular disease and especially of stroke. In this new edition of Neurosonology and Neuroimaging of Stroke, this noninvasive, realtime imaging method has been given expanded coverage, particularly for its clinical utility. As in the first edition, the new edition offers both a clear overview of the principles of neurosonology and a casebook exploring critical cerebrovascular problems. Ultrasound anatomy, technical aspects of clinical application, and the advantages and limitations of ultrasound are reviewed and contrasted to conventional, magnetic resonance, and computed tomography angiography. Forty-five selected cases from the authors' extensive collections at Charite - Universitatsmedizin Berlin and the Center of Neurology in Bad Segeberg, Germany, are then discussed. The patient histories and working diagnoses are followed by detailed assessments of the extra- and intracranial color-coded duplex sonographic findings and additional diagnostic procedures. The relevant clinical aspects are presented in a compact, comprehensible way, and for the majority of the cases videos are available in the Thieme MediaCenter, providing further in-depth understanding of the full potential of the method. Features: Complete extra- and intracranial arterial and venous ultrasound examination New techniques: ultrasound fusion imaging, ultrafast ultrasound, contrast application More than 1,300 high-quality illustrations, including full-color duplex images Fifteen newly selected cases on conditions such as subarachnoid hemorrhage and dural fistula, as well as rare stroke causes including sickle cell disease and reversible cerebral vasoconstriction syndrome Revision of many cases from the first edition More than 60 new video clips (for a total of 130) available at the Thieme MediaCenter, bringing ultrasound anatomy and challenging cases to your monitor! Neurosonology and Neuroimaging of Stroke, Second Edition, offers neurologists, neuroradiologists, and all physicians treating patients with cerebrovascular disease an authoritative introduction and guide to this powerful diagnostic tool.
This second edition presents core clinical neuroanesthesia and neurointensive care knowledge in a practical, user-friendly format.
Video Atlas of Neurosurgery: Contemporary Tumor and Skull Base Surgery is a unique resource that consists of 40 procedural videos and a concise companion book to reinforce your understanding of the material. Dr. Alfredo Quiñones-Hinojosa brings together a group of outstanding faculty, residents, and fellows lead by Dr. Jordina Rincon-Torroella, who carefully designed, assembled, and edited each chapter. The videos are enhanced through the inclusion of intraoperative photos, anatomical dissections, outstanding anatomical drawings, and animations that detail key steps and provide the experience of viewing a real-time surgery. Whether consulted together or independently of each other, the video and print content deliver all of the expert knowledge you need for effectively planning and understanding tumor and skull base surgeries. - Step-by-step, state-of-the-art videos – 40 in total – are accessible through Expert Consult and narrated by Dr. Quiñones-Hinojosa. - Each video is around 10 minutes with a total running time of over 6 hours - Videos highlight key surgical anatomy, focusing special attention on the relationship between lesions and important landmarks. - Procedures are broken down step-by-step for easy overview and comprehension. - Covers advanced techniques such as: intraoperative brain mapping; intraoperative assessment of resection through iMRI; fluorescence imaging; brain stem mapping techniques; combined open-and-endoscopic approaches, cortical-subcortical stimulation in awake surgery; and more. - Dedicated neurosurgical artwork by Devon Stuart includes superb figures that depict the surgical neuroanatomy and approaches in a step-wise fashion. - Chapters are presented from the less complex, more common surgeries to the most complex and cutting-edge procedures that may require multidisciplinary approaches.
The second, revised edition of this successful textbook provides an up-to-date description of the use of preoperative fMRI in patients with brain tumors and epilepsies. State of the art fMRI procedures are presented, with detailed consideration of practical aspects, imaging and data processing, normal and pathological findings, and diagnostic possibilities and limitations. Relevant information on brain physiology, functional neuroanatomy, imaging technique, and methodology is provided by recognized experts in these fields. Compared with the first edition, chapters have been updated to reflect the latest developments and in particular the current use of diffusion tensor imaging (DTI) and resting-state fMRI. Entirely new chapters are included on resting-state presurgical fMRI and the role of DTI and tractography in brain tumor surgery. Further chapters address multimodality functional neuroimaging, brain plasticity, and pitfalls, tips, and tricks.