Download Free Update On Multiple Myeloma Book in PDF and EPUB Free Download. You can read online Update On Multiple Myeloma and write the review.

This is a comprehensive, state-of-the-art guide to the diagnosis, treatment, and biology of multiple myeloma and related plasma disorders. Edited and written by a multidisciplinary group of recognized authorities from the Mayo Clinic, it presents clear guidelines on diagnosis and therapy and covers all aspects of multiple myeloma, from molecular classification and diagnosis, to risk stratification and therapy. Closely related plasma cell disorders such as solitary plasmacytoma, Waldenstrom macroglobulinemia, and light chain amyloidosis are discussed in detail as well. The book addresses often overlooked topics, including the role of radiation therapy, vertebral augmentation, and supportive care. Our understanding of this group of disorders is developing at an unprecedented rate, and Multiple Myeloma meets the need among oncologists and hematologists for a clear, timely, and authoritative resource on their biology, diagnosis, and treatment.
This book is a comprehensive overview of the recent developments in the clinical and research fields of multiple myeloma. It is divided into three main sections that cover a wide range of topics, including: epidemiology and pathogenesis of the disease, genetic targets and pathways, resistance to novel therapies, angiogenesis and anti-angiogenesis, hematopoietic stem cell transplantation, role of radiology and radiotherapy in myeloma, infectious complications, and management of multiple myeloma in resource-poor countries.
This handbook is an in-depth and comprehensive guide to the pathophysiology, diagnosis, staging, treatment and management of patients with multiple myeloma. The Handbook was commissioned to address an unmet need for a book of this kind in the myeloma field and to provide busy healthcare professionals with an informative and educational review of the current and emerging treatment recommendations for multiple myeloma. Myeloma is a type of bone marrow cancer arising from plasma cells and is the second most common form of bone marrow cancer, but represents just 1% of all cancers. The causes of myeloma are not fully understood but it is thought to be caused by an interaction of both genetic and environmental factors. This Handbook discusses these issues as well the latest developments in the field and will be an invaluable source of topical information for all healthcare professionals with an interest in multiple myeloma.
Since the original publication of Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Allogeneic hematopoietic stem cell transplantation (HSC) has undergone several fast-paced changes. In this second edition, the editors have focused on topics relevant to evolving knowledge in the field in order to better guide clinicians in decision-making and management of their patients, as well as help lead laboratory investigators in new directions emanating from clinical observations. Some of the most respected clinicians and scientists in this discipline have responded to the recent advances in the field by providing state-of-the-art discussions addressing these topics in the second edition. The text covers the scope of human genomic variation, the methods of HLA typing and interpretation of high-resolution HLA results. Comprehensive and up-to-date, Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Second Edition offers concise advice on today's best clinical practice and will be of significant benefit to all clinicians and researchers in allogeneic HSC transplantation.
Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy, including in particular the approval of novel and first-in-class drugs such as thalidomide, bortezomib, and lenalidomide. This book, written by internationally acknowledged experts, covers a wide range of topics relating to multiple myeloma, including history, epidemiology, pathophysiology, clinical features, staging, and prognostic systems. The principal focus, however, is on therapy, with detailed information on the various promising treatment options which give hope that this cancer will be transformed into a chronic disease or even become curable. Individualized therapy and the variety of supportive treatment options, as described in this volume, will help in achieving this goal, as well as in reducing adverse events and improving quality of life.
This book is a comprehensive source of up-to-date information on plasma cell neoplasms. Key features include the provision of new criteria for the diagnosis of symptomatic multiple myeloma requiring treatment and the description of novel therapies for myeloma and other plasma cell neoplasms that have only very recently been licensed by the U.S. Food and Drug Administration. Examples include lenalidomide as first-line therapy, panobinostat in combination with bortezomib plus dexamethasone for relapsed/refractory myeloma, ibrutinib for Waldenström’s macroglobulinemia, and new therapeutic regimens for systemic amyloidosis and POEMS syndrome. Information is also provided on drug combinations that have shown encouraging results and are very near to approval. Other important aspects covered in the book are the role of different imaging modalities in workup and the significance of newly acquired data relating to prognosis and minimal residual disease. Readers will find Multiple Myeloma and Other Plasma Cell Neoplasms to be a rich source of knowledge that will be invaluable in improving patient management.
This book provides the clinician with concise, practical guidance on risk stratification and therapeutic decision making in patients with multiple myeloma. In addition, the available clinical trial and research data are summarized into meaningful reviews and evidence-based recommendations for treatment are presented. The coverage encompasses all phases and forms of disease, including high-risk myeloma. Over recent decades, greater understanding of the biology of myeloma has fostered the development of new, more effective drugs, leading to remarkable improvements in survival. To continue this momentum, several recent prospective trials have aimed to identify further potential therapeutic targets or to evaluate various combinations of anti-myeloma agents. The increasing abundance of management options makes the decision making complex in different phases of the disease. This book will offer the clinician valuable assistance in the choice and sequencing of therapies, highlighting the need for a personalized approach that reflects the growing recognition that myeloma is not one uniform disease.
This handbook provides up-to-date and comprehensive treatment of all plasma cell disorders, including both common and rare disorders. All disease aspects from pathogenesis to most recent therapy are covered. The text originates from the Mayo Clinic, the world's most experienced institution in plasma cell disorders. Comprehensive treatise on all plasma cell disorders from the gene level to treatment of emergencies Chapters are uniformly organized for easy data access All authors are important authorities in their field with extensive clinical experience
A practical guide to the clinical use of serum and urine electrophoresis and also includes coverage of immunofixation electrophoresis. These techniques are essential in the accurate identification of monoclonal gammopathies and the diagnosis of multiple myeloma and related disorders. Interpretation is often challenging even for the experienced practitioner. Throughout the book the emphasis is on indications and practical aspects of interpreting test results. Particular attention is paid to differentiating false negative and false positive test results. The text provides clear, practical discussions extensively supported by representative images to guide the reader to accurate identification of specimens.
NEW YORK TIMES BESTSELLER • WITH A NEW PREFACE BY THE AUTHOR • A powerful memoir of a dramatic year spent battling cancer and reflecting on a long, happy, and lucky life—from the bestselling author of The Greatest Generation, whose iconic career in journalism has spanned more than fifty years Tom Brokaw has led a fortunate life, with a strong marriage and family, many friends, and a brilliant journalism career culminating in his twenty-two years as anchor of the NBC Nightly News and as bestselling author. But in the summer of 2013, when back pain led him to the doctors at the Mayo Clinic, his run of good luck was interrupted. He received shocking news: He had multiple myeloma, a treatable but incurable blood cancer. Friends had always referred to Brokaw’s “lucky star,” but as he writes in this inspiring memoir, “Turns out that star has a dimmer switch.” Brokaw takes us through all the seasons and stages of this surprising year, the emotions, discoveries, setbacks, and struggles—times of denial, acceptance, turning points, and courage. After his diagnosis, Brokaw began to keep a journal, approaching this new stage of his life in a familiar role: as a journalist, determined to learn as much as he could about his condition, to report the story, and help others facing similar battles. That journal became the basis of this wonderfully written memoir, the story of a man coming to terms with his own mortality, contemplating what means the most to him now, and reflecting on what has meant the most to him throughout his life. Brokaw also pauses to look back on some of the important moments in his career: memories of Nelson Mandela, the Dalai Lama, the fall of the Berlin Wall, the morning of September 11, 2001, in New York City, and more. Through it all, Brokaw writes in the warm, intimate, natural voice of one of America’s most beloved journalists, giving us Brokaw on Brokaw, and bringing us with him as he navigates pain, procedures, drug regimens, and physical rehabilitation. Brokaw also writes about the importance of patients taking an active role in their own treatment, and of the vital role of caretakers and coordinated care. Generous, informative, and deeply human, A Lucky Life Interrupted offers a message of understanding and empowerment, resolve and reality, hope for the future and gratitude for a well-lived life. Praise for A Lucky Life Interrupted “It’s impossible not to be inspired by Brokaw’s story, and his willingness to share it.”—Los Angeles Times “A powerful memoir of battling cancer and facing mortality . . . Through the prism of his own illness, Brokaw looks at the larger picture of aging in America.”—Booklist (starred review) “Moving, informative and deeply personal.”—The Daily Beast “The former NBC News anchor has applied the fact-finding skills and straightforward candor that were his stock in trade during his reporting days to A Lucky Life Interrupted.”—USA Today “Brokaw doesn’t paste a smiley face on his story. Again and again, the book returns to stories of loss but also of grace, luck and the beauty of having another swing at bat.”—The Washington Post “Engaging . . . [with] the kind of insight that is typical of Mr. Brokaw’s approach to life and now to illness.”—The Wall Street Journal “Powerful and courageous . . . [Brokaw] looks ahead to the future with hope.”—Bookreporter