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Beginning with a tour of the brain, Dr. Hedaya explains how the brain works and how brain function relates to physical symptoms and cognitive and emotional well-being. He explains how biological psychiatrists consider the biology of the individual as an integral part of the whole picture and demonstrates a new way of conceptualizing clinical problems. Understanding Biological Psychiatry provides information in three basic areas: Chapters 1 and 2 outline basic scientific foundations and core concepts in biological psychiatry; chapters 3 and 4 review biological theories and medical mimics of the major psychiatric disorders; chapters 5 and 6 discuss medication and practical issues, including the basics of psychotropic medications and their role in the biopsychosocial approach. At the heart of this book is the author's proposal for a working alliance between therapists and psychiatrists - an important goal in today's growing managed care environment. The book has a practical bent, discussing, for example, when and how to refer to a psychiatrist, even describing how to explain this new perspective to a patient. The author's conversational style, as well as many figures, tables, and case illustrations, makes Understanding Biological Psychiatry a guide that is sure to be well-read and often referred to by therapists and physicians, as well as psychiatrists wanting to brush up on the biology of the mind.
A Textbook of Biological Psychiatry integrates the basic science concerning brain mechanisms of psychiatric disorders alongside surveys of present standard clinical treatment. Organized in a coherent and easy to follow structure, chapters expand across different levels of analysis, from basic mechanisms to clinical practice. This comprehensive reference provides an integrative treatment of the biochemistry of neurotransmission, behavioral pharmacology, and clinical aspects of psychiatric problems including depression, manic-depression, and mood disorders. Other chapters address the biological mechanisms and treatment of depression, anxiety, panic, obsessive-compulsive disorder, and addictions. The editor concludes with a perspective on the future of the field and prospects for understanding and effectively treating mood and anxiety disorders.
Biological psychiatry has dominated psychiatric thinking for the past 40 years, but the knowledge base of the discipline has increased substantially more recently, particularly with advances in genetics and neuroimaging. The third edition of Biological Psychiatry has been thoroughly updated taking into account these developments. As in the earlier editions of the book, there are comprehensive reviews and explanations of the latest advances in neurochemistry, neuroanatomy, genetics and brain imaging— descriptions not only of methodologies but also of the application of these in clinical settings. It is within this context that there is a considerable emphasis in the book on brain–behaviour relationships both within and without the clinical setting. This edition has been enhanced by the inclusion of new chapters, one on anxiety and another on motivation and the addictions. The chapter that relates to treatments has been extended to include the latest information on brain stimulation techniques. The overall book is well illustrated in order to help with an understanding of the text. For the third edition, Professor Michael Trimble has been joined by Professor Mark George as co-author. These are two of the world's leading biological psychiatrists who both have considerable clinical as well as research experience which they have brought to the book. Unlike multiauthored texts, it has a continuity running through it which aids understanding and prevents repetition. This book is strongly recommended for all practising psychiatrists and trainees wishing for an up-to-date, authoritative, easy to digest and acessible review of the latest advances and conceptualizations in the field. It will also appeal to neurologists interested in neuropsychiatry and biological psychiatry or the psychiatric aspects of neurological disorders, as well as other practising clinicians (psychologists, social workers, nurses) in the mental health field.
A new computational and dimensional approach to understanding and classifying mental disorders: modeling key learning and decision-making mechanisms across different mental disorders. Even as researchers look for neurobiological correlates of mental disorders, many of these disorders are still classified solely according to the manifestation of clinical symptoms. Neurobiological findings rarely help diagnose a specific disease or predict its outcome. Although current diagnostic categories are questionable (sometimes labeling common states of human suffering as disorders), traditional neuroimaging approaches are not sophisticated enough to capture the neurobiological markers of mental disorder. In this book, Andreas Heinz proposes a computational and dimensional approach to understanding and classifying mental disorders: modeling key learning and decision-making mechanisms across different mental disorders. Such an approach focuses on the malleability and diversity of human behavior and its biological underpinnings. Heinz explains basic learning mechanisms and their effects on human behavior, focusing not on single disorders but on how such mechanisms work in a multitude of mental states. For example, he traces alterations in dopamine-reinforcement learning in psychotic, affective, and addictive disorders. He investigates to what extent these basic dimensions of mental disorders can account for such syndromes as craving and loss of control in addiction, positive and negative mood states in affective disorders, and the altered experience of self and world associated with psychotic states. Finally, Heinz explores the clinical and therapeutic implications of such accounts. He argues that a focus on learning mechanisms, with its emphasis on human creativity and resilience, should help reduce the stigma of mental disorder.
“Superb… a nuanced account of biological psychiatry.” —Richard J. McNally In Mind Fixers, “the preeminent historian of neuroscience” (Science magazine) Anne Harrington explores psychiatry’s repeatedly frustrated efforts to understand mental disorder. She shows that psychiatry’s waxing and waning theories have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors. Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future.
Biological Markers in Psychiatry and Neurology is a collection of papers that details the advancement in the understanding of the biological markers that stems from psychiatric and neurological pathologies. The text first covers topics about various biological markers, such as neurochemical, enzymatic, membrane, receptors, endocrine, and physiological. Next, the selection examines the relationship between alcohol abuse and biological papers. The next part covers the genetic aspects of biological markers. The text also deals with use of tomography and modeling theory. The book will be of great use to students, researchers, and practitioners of neurology and psychiatry. Psychologists will also benefit from the text.
Lately, it seems that not a day passes without the media proclaiming yet another sensational breakthrough in the search for the physical origins of mental illness. But beyond all the fanfare and media hype, is there a single shred of hard, empirical evidence to substantiate the existence of "a gene for alcoholism," or "the brain chemistry behind schizophrenia"? More to the point, in fact, is it scientifically sound to limit the search for the roots of mental illness to processes occurring within the body, while dismissing socioeconomic, familial, and experiential influences as, at best, mere "triggering mechanisms"? And, if not, what harm is being done by psychiatry's current obsession with these somatic chimeras? This groundbreaking book offers answers to those questions and more. While Dr. Ross and Professor Pam clearly assert from the outset that biological psychiatry "is dominated by a reductionist ideology which distorts and misrepresents much of its research," this is by no means a raw polemic voiced by an overzealous opposition. Instead, it is a reasoned discourse based on a clear-sighted and methodical examination of the professional literature. Contributors to this volume include distinguished researchers and clinicians from the fields of psychiatry, psychology, sociology, and psychopharmacology. Their common purpose in coming together was to alert the mental health community to the ideological blind spots and conceptual errors in the basic logic and methodology of biological psychiatry, to demonstrate the need for a more scientifically based psychiatric practice, and to suggest alternative approaches to understanding and treating mental illness. Readers will find their arguments stimulating, provocative, and highly persuasive. Among the cutting-edge issues they explore are: the historical origins of biological psychiatry; genetics and mental illness; the current state of psychiatric training; psychopharmacology and drug therapy; the public health, legal, and ethical implications of biological psychiatry; and the funding, power, and politics of research. This book is essential reading for all mental health professionals. It also has many important things to say to health care administrators, political analysts, and public policy-makers. Of related interest . . . INSANITY The Idea and Its Consequences Thomas Szasz In this provocative book, Dr. Thomas Szasz, one of the most celebrated and controversial psychiatric thinkers of our time, presents a carefully crafted, systematic analysis of the precise character and practical consequences of the idea of mental illness. His findings and opinions have captured the attention of organized psychiatry and given everyone concerned with the human condition a better understanding of this almost universally misunderstood "disease." 1990 (0-471-52534-0) 432 pp. CRUEL COMPASSION Psychiatric Control of Society's Unwanted Thomas Szasz Cruel Compassion is the capstone of Thomas Szasz's critique of psychiatric practices. Reexamining psychiatric interventions from a cultural-historical and political-economic perspective, Szasz demonstrates that the main problem that faces mental health policymakers today is adult dependency. He gives us a sobering look at some of our most cherished notions about our humane treatment of society's unwanted and about ourselves as a compassionate and democratic people. 1994 (0-471-01012-X) 260 pp.
This book explores the underlying biology associated with the pathology of mental health disorders and the related nervous system. Fully revised for this third edition, each chapter has been updated to include the latest research, ideas and concepts in each field, and includes a new chapter on sleep. Integrating up-to-date pharmacological and genetic knowledge with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, drug abuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders, and sleep. Accessible and engaging, this is an essential text for mental health students, practitioners and educators.
Brought together for the first time in a single volume, these eight important and fascinating essays by Nobel Prize-winning psychiatrist Eric Kandel provide a breakthrough perspective on how biology has influenced modern psychiatric thought. Complete with commentaries by experts in the field, Psychiatry, Psychoanalysis, and the New Biology of Mind reflects the author's evolving view of how biology has revolutionized psychiatry and psychology and how potentially could alter modern psychoanalytic thought. The author's unique perspective on both psychoanalysis and biological research has led to breakthroughs in our thinking about neurobiology, psychiatry, and psychoanalysis -- all driven by the central idea that a fuller understanding of the biological processes of learning and memory can illuminate our understanding of behavior and its disorders. These wonderful essays cover the mechanisms of psychotherapy and medications, showing that both work at the same level of neural circuits and synapses, and the implications of neurobiological research for psychotherapy; the ability to detect functional changes in the brain after psychotherapy, which enables us, for the first time, to objectively evaluate the effects of psychotherapy on individual patients; the need for animal models of mental disorders; for example, learned fear, to show how molecules and cellular mechanisms for learning and memory can be combined in various ways to produce a range of adaptive and maladaptive behaviors; the unification of behavioral psychology, cognitive psychology, neuroscience, and molecular biology into the new science of the mind, charted in two seminal reports on neurobiology and molecular biology given in 1983 and 2000; the critical role of synapses and synaptic strength in both short- and long-term learning; the biological and social implications of the mapping of the human genome for medicine in general and for psychiatry and mental health in particular; The author concludes by calling for a revolution in psychiatry, one that can use the power of biology and cognitive psychology to treat the many mentally ill persons who do not benefit from drug therapy. Fascinating reading for psychiatrists, psychoanalysts, social workers, residents in psychiatry, and trainees in psychoanalysis, Psychiatry, Psychoanalysis, and the New Biology of Mind records with elegant precision the monumental changes taking place in psychiatric thinking. It is an invaluable reference work and a treasured resource for thinking about the future.