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The Government and authorities in Brazil were faced with a tragic accident in Goiânia resulting from the misuse of a strongly radioactive medical teletherapy source not under radiation protection surveillance. The present report is divided into four parts: a chronology of destruction of the source, discovery of the accident and initial response; a description of the human consequences and the dosimetry and treatment of seriously exposed and contaminated persons; an account of the assessment of the environmental contamination and the remedial actions taken; and observations and recommendations. Appendices and annexes give an assessment of the effectiveness of international co-operation in the emergency response, and provide further information on: public communications; radiological survey equipment; guidelines for the discharge of patients; radiological protection; chemical decontamination; and the lessons learned.
This book is a unique in-depth and comprehensive reference that covers all surgically relevant thyroid and parathyroid diseases and presents the latest information on their management. International authorities discuss operative techniques and treatments in detail and explain the rationales for their favored approaches. The topics of this second edition include the description of surgically relevant pathologies, preoperative surgical evaluation, decision making, and operative strategies for the various thyroid and parathyroid diseases. In addition, experts present the molecular basis for thyroid neoplasia, review the current understanding of the genetics of inherited thyroid and parathyroid diseases, and discuss the management of recurrent and locally invasive thyroid cancer. Evolving modern operative techniques such as neuromonitoring and minimally invasive (videoscopic) approaches to the thyroid and parathyroids are also covered.
This book explains in a clear and simple way what life is and how it flows within our cells, between people and through people. It is a practical manual that will help us to "feel" life, to vibrate and breathe the life inside of our bodies and of all living beings. A key focus of this work is how emotional impact affects our pericardium, which is the membrane that envelops, maintains and protects the heart.
In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar row stem cells or spermatogonia.
On 21 June 1990 a fatal radiological accident occurred at an industrial irradiation facility at Soreq, Israel. An operator entered the irradiation room by circumventing safety systems and was acutely exposed, with an estimated whole body dose of 10-20 Gy. The accident, like earlier accidents at similar irradiators, was the consequence of the contravention of operating procedures. An IAEA review team investigated the causes of the accident. This report presents its findings and recommendations and describes the clinical management of the patient, particularly of the haematological phase. The medical treatment included the use of emerging therapies with haematopoietic growth factor drugs which may rescue the overexposed patient, albeit in this case only temporarily. The report is intended for regulatory authorities responsible for the regulation and inspection of irradiators, operating organizations and physicians who may need to treat overexposed patients.
This textbook covers many aspects of radiation, radiotherapy and their effects. It includes a discussion of recent advances, such as the molecular basis of cellular effects and cell radiosensitivity, radiocarcinogenesis and how radiotherapy can affect normal and neoplastic tissues.