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It is now thirty years since William Montagna and Richard Ellis edited 'The Biology of Hair Growth". In his introduction, Stephen Rothman, of the University of Chicago, USA and one of the driving forces behind research on skin at the time, wrote: 'The pilary system is a perfect micr9cosmic structure. In this microcos mos we find birth, development, ageing and death, activity and rest, color for mation and decolorification, greasiness and dryness, infection and sterilization, hypertrophy and atrophy, Qenign tumours and malignant ones." He foresaw the human pilary system as a model for the study of a multitude of human diseases including ageing and cancer. It was not, how ever, until the seventies that the development of micro-biochemical tech niques indeed allowed the use of the human hair follicle as a convenient biopsy tissue for Biomedical Research in general. Measurement of enzyme activities, and important co-factors, and culturing of cells from single follicles all became possible. In the eighties dermal papilla cells were grown in cul ture and this opened the way to study hair differentiation in vitro. Studying hair differentiation is, in fact, studying growth regulation and it is this aspect that by far transcends the importance of studying hair growth itself. Let us not forget that metastatic prostate cancer is treated with the same drug -cyproterone acetate -that is used for the treatment of alopecia and hirsutism in women.
Hair disorders have become a central social and psychological issue and patients now have increasing demands and expectations. Written by world-renowned experts, this lavishly illustrated book provides the latest scientific aspects of hair biology, up to date knowledge on hair diagnosis and treatment options as well as hair removal and restoration techniques. The content is divided into three sections: basic aspects of hair growth; hair and scalp disorders; and fotoepilation, surgery and hair cosmetics. In addition, coverage is enhanced with unique sections on hair in different ages and in art, on ethnic hair and in forensic investigations.
Hair is a major component of the body's tissue system that contributes to the individual's make up and confers a large degree of personal identity. Apart from its visible façade, hair also has a functional role. It has an unique structure and complex molecular development. The very nature of hair makes it a suitable marker for the prognosis of disease. Hair can also be used to screen for toxins and changes in the diet. However, there are currently no suitable publications available that describe hair in a rational scientific context. This handbook provides an academic approach to hair in health and disease. Divided into five sections the Handbook of Hair in Health and Disease provides an insight into hair growth and loss, molecular and cellular biology of hair, dietary toxicity and pathological history, diseases and treatments of hair, as well as shampoos and conditioners. Unique features of each chapter in this volume include relevant and useful 'Key facts' which highlight interesting or important findings of the specific subjects and 'Summary points' that will give a clear overview of the subjects treated in each chapter. The Handbook of Hair in Health and Disease will be essential to a variety of users, such as trichologists, doctors and nurses and all those interested or working within the area of hair health. This includes nutritionists and dieticians, scientific beauticians, health workers and practitioners, college and university lecturers and undergraduate and graduate students.
The Biology of Hair Growth is based on a conference on The Biology of Hair Growth, sponsored by the British Society for Research on Ageing, held at the Royal College of Surgeons, in London, 7-9 August 1957. The papers presented at this conference, and a few others, have been gathered in this book to serve as a source reference for all those interested in research on hair and hair growth. The application of modern methods in histology, cytology, histochemistry, physiology, electron microscopy, the use of radioactive isotopes, and modern biochemical techniques have given greater insight into the phenomena of growth and differentiation of hair follicles than ever before. The book opens with a chapter on the embryology of hair. Separate chapters follow on the anatomy and histochemistry of the hair follicle; the electron microscopy of keratinized tissues; the chemistry of keratinization; the mitotic activity of the follicle; and the the vascularity and patterns of growth of hair follicles. Subsequent chapters deal with behavior of pigment cells and epithelial cells in the hair follicle; the nature of hair pigment; the effects of nutrition on hair growth; and effects of chemical agents, ionizing radiation, and particular illnesses on hair roots.
“Aged? But he does not appear aged, just look, his hair has remained young!” Marcel Proust, In Search of Lost Time (1913–27) The appearance of hair plays an important role in peoples’ overall physical appe- ance and self-perception. With today’s increasing life-expectation, the desire to look youthful plays a bigger role than ever. The hair care industry has become aware of this, and capable to deliver active products that are directed toward meeting this c- sumer demand. The discovery of pharmacological targets and the development of safe and effective drugs such as minoxidil and fnasteride also indicate strategies of the drug industry for maintenance of healthy and beautiful hair in the young and old. The study of hair aging focuses on two main streams of interest: On the one hand, the esthetic problem of aging hair and its management, in other words everything that happens outside the skin; on the other hand, the biological problem of aging hair, in terms of microscopic, biochemical, and molecular changes, in other words the “secret life” of the hair follicle in the depth of the skin. Hair aging comprises hair shaft aging, and aging of the hair follicle. The former involves weathering and photoaging of the hair shaft, while the latter manifests as decrease of melanocyte function (graying) and decrease in hair production (alopecia).
The only comprehensive book on the subject of hair loss! Highly illustrated, with 250 new color photographs, this resource covers the basic science, diagnosis, and treatment of all problems related to hair. Conditions covered include childhood hair loss, excessive body hair, various types of adult balding, and loss due to medical conditions, trauma, and medications. The new Second Edition emphasizes various new diagnosis and treatment methods including popular, recently approved remedies.
Human hair is the subject of a wide range of scientific investigations. Its chemical and physical properties are of importance to the cosmetics industry, forensic scientists, and to biomedical researchers. This updated and enlarged fourth edition continues the tradition of its predecessor as being the definitive monograph on the subject. It now contains new information on various topics including: chemical hair damage, the cause of dandruff, skin and eye irritation, hair straightening, and others. Chemical and Physical Behavior of Human Hair is a teaching guide and reference volume for cosmetic chemists and other scientists in the hair products industry, academic researchers studying hair and hair growth, textile scientists, and forensic specialists.
The first edition of "Testosterone: Action, Deficiency, Substitu tion" was published in 1990. Since then our understanding of the hormone that turns males into men has tremendously increased. Therefore, the editors felt that a second extended edition of the book is warranted in order to summarize established and recent findings in the field and to present the reader with an up-to-date is reflected by the textbook. The increased mass of knowledge growth of the volume from 14 to 20 chapters. In the updated edition the biochemistry and metabolism of androgens have been complemented by extensive information on the molecular biology of the androgen receptor and its disorders. The key role of testosterone in spermatogenesis is now better de fined. We have a more complete understanding of the psychotro pic effects of testosterone and know so much about the different target organs and functions that individual chapters deal with testosterone and the prostate, lipids and the cardiovascular sys tem, hair, bones and muscles. The general chapter on pharmacol ogy and clinical uses of testosterone, in particular in male hypo gonadism, is extended by pharmacokinetic studies on testoster one preparations and individual substitution modalities using testosterone esters as well as implants and advanced trans dermal applications. The physiologic basis and possible clinical applica tions of testosterone in non-gonadal diseases, in male senes cence, in hormonal male contraception and in transsexuals are discussed. The last chapter describes the role of "investigative" steroid biochemistry applied to tracking anabolic steroid abuse.
Written to address the growing trend of hair loss in ethnic populations, The Fundamentals of Ethnic Hair: A Dermatologist's Perspective elucidates the science of curly hair, demystifies prevailing hair styling trends, and presents practical advice for minimizing the harmful effects of these hair styling practices. Written from a dermatologist's perspective, this textbook seamlessly blends science and practical management. Chapters include physical and chemical properties of the hair, thermal and chemical straightening, extensions, razor bumps and special cultural considerations.