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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
An anthology of the literature of tobacco.
Maurice Duke and Daniel P. Jordan vividly describe the colorful life and times of one of the South's—and America's—most important businesses and provide insight into how luck, management practices, and personalities helped the company rise to international prominence. Universal Leaf Tobacco Company, the world's largest independent leaf tobacco dealer, is one of the major buying arms for tobacco manufacturers worldwide, selecting, purchasing, processing, and storing leaf tobacco. The story opens during the aftermath of the Civil War when Southerners realized once again the worldwide potential of their native crop. The authors follow the company from its incorporation 1918 through one of the first hostile takeover attempts in American business, to its evolution in 1993 into Universal Corporation, a worldwide conglomerate with a number of products including tobacco. Based on scholarly research and over two hundred interviews with past and present Universal employees, this objective saga reveals much about American business and economic history.
A Choice Reviews Editors' Pick Through the rise and fall of empires, ideologies, and economies, tobacco grown on the tiny island of Cuba has remained an enduring symbol of pleasure and extravagance. Cultivated as one of the first reliable commodities for those inhabitants who remained after conquistadors moved on in search of a mythical wellspring of gold, tobacco quickly became crucial to the support of the swelling Spanish Empire in the seventeenth and eighteenth centuries. Eventually, however, tobacco became one of the final stabilizing forces in the empire, and it ultimately proved more resilient than the best laid plans of kings and queens. Tobacco, and those whose livelihoods depended on it, shrugged off the Empire's collapse and pressed on into the twentieth century as an economic force any state or political power must reckon with. Cosner explores the history of this golden leaf through the personal narratives of farmers, bureaucrats, and laborers, all struggling to build an independent and lucrative economic engine. Through conquest, rebellion, colonial and imperial schemes, and the eventual Communist revolution, Cuban tobacco and cigars became a luxury item that commanded loyalty that defied mere borders or embargoes. Ultimately, The Golden Leaf is a story of two carefully cultivated products: Cuban tobacco, and its lofty reputation.
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