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This book, now in its fourth edition, aims to promote a deeper understanding of the scientific and clinical basis of nuclear medicine and the new directions in medical imaging. The new edition has been revised and updated significantly to reflect recent changes and to ensure that the contents are in line with likely future directions. In addition to that, chapters have been reorganized in order to simplify the contents and to increase the readability. The book starts by providing essential information on general pathophysiology, cell biology and biologic effects of ionizing radiation followed by the mechanisms of radiopharmaceutical localization in different tissues and cells. This is followed by a series of chapters that covers all relevant organ systems presenting the basic knowledge of anatomy, physiology, and pathology and relating them to the clinical utilization of various scintigraphic modalities. The final chapter is devoted to the basis of therapeutic applications of nuclear medicine. The book will prove invaluable to all with an interest in the pathophysiologic basis of Nuclear Medicine, including nuclear medicine professionals, radiologists, surgeons, pediatricians and internal medicine physicians.
This Synopsis of Nuclear Medicine Pathophysiology arose from the recognition that there is a need for a compact, readable account of this complex and important subject. The book concisely describes relevant anatomic and physiologic considerations for each organ system and the pathophysiologic features of different relevant diseases and relates them to the scintigraphy of each system. It thereby provides an informative synopsis of the pathophysiologic basis of nuclear medicine and molecular imaging. The volume will serve as a quick reference that will help the reader to understand different diagnostic scintigraphic patterns and to select appropriate treatment modalities based on functional imaging. It will prove useful to undergraduates and postgraduates as well as to practitioners in clinical and research fields.
This book, now in an extensively revised second edition, summarizes the basic principles of nuclear medicine and describes the clinical applications of commonly used nuclear medicine procedures and techniques. Readers will find clear explanation of clinical indications, the pathophysiological basis of functional procedures, and the complementary role of nuclear medicine and molecular imaging in relation to diagnostic radiology. Throughout, emphasis is placed on the added diagnostic value offered by the new hybrid imaging modalities. The various therapeutic applications of nuclear medicine are also discussed. Compared with the first edition, technical details have been significantly simplified. The book will be an ideal introduction to nuclear medicine for medical students and will serve as an excellent quick reference for referring physicians, enabling them to utilize this modern medical specialty more efficiently.
I. BASIC PRINCIPLES -- 1. Radiopharmaceuticals -- 2. Nuclear Medicine Physics -- 3. Radiation Detection and Instrumentation -- 4. SPCT and PET -- II. CLINICAL NUCLEAR MEDICINE -- 5. Endocrine System -- 6. Skeletal System -- 7. Hepatobiliary System -- 8. Genitourinary System -- 9. Oncology 6 Single Photon -- 10. Oncology 6 Positron Emission Tomography -- 11. Gastrointestinal System -- 12. Infection and Inflammation -- 13. Central Nervous System -- 14. Cardiac System -- 15. Pulmonary System -- 16. Pearls, Pitfalls and Frequently Asked Questions.
Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
"First and foremost, Dr. Chandra welcomes Dr. Arman Rahmim as a coauthor for this new edition of the book"--
Get the essential tools you need to make an accurate diagnosis with Nuclear Medicine: The Requisites! The newest edition of his bestselling volume by Drs. Harvey Ziessman, Janis O'Malley, and James Thrall delivers the conceptual, factual, and interpretive information you need for effective clinical practice in nuclear medicine imaging, as well as for certification and recertification review. Prepare for the written board exam and for clinical practice with critical information on nuclear medicine physics, detection and instrumentation, SPECT and PET imaging, and clinical nuclear medicine imaging. Get the best results from today's most technologically advanced approaches, including hybrid imaging, PET/CT, and SPECT/CT, as well as recent developments in instrumentation, radiopharmaceuticals, and molecular imaging. Clearly visualize the findings you're likely to see in practice and on exams with nearly 200 vibrant new full-color images. Access the fully searchable text and downloadable images online at www.expertconsult.com.
This Fourth Edition reflects the significant recent progress that has occurred in functional brain imaging, particularly the increased use of PET/SPECT, the use of SPECT and PET in movement disorders and dementia, and advances in radiopharmaceutical development and instrumentation. Chapter topics include PET physics and instrumentation, PET radiopharmaceuticals, SPECT radiopharmaceuticals, and technical factors. The entire book has been thoroughly revised to reflect an appropriate balance between SPECT and PET applications. Highlights of this edition include a new chapter on neuroreceptor imaging and kinetic modeling, a new chapter on brain imaging in movement disorders, and significant updates on SPECT radiopharmaceuticals.