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Current, comprehensive, and evidence-based, Kaplan's Cardiac Anesthesia: Perioperative and Critical Care Management, 8th Edition, offers practical guidance from today's international leaders in cardiac anesthesiology, helping you to optimize perioperative outcomes, avoid complications, and ensure maximum patient safety. Dr. Joel A. Kaplan, along with an expert team of associate editors, guides you through today's clinical challenges, including expanded coverage of critical care, the newest approaches to perioperative assessment and management, state-of-the art diagnostic techniques, and cardiovascular and coronary physiology. - Covers the full spectrum of contemporary cardiothoracic anesthesia practice, including preoperative assessment, physiology, pharmacology, monitoring, transesophageal echocardiography, coagulation, specific cardiac procedures, extracorporeal circulation, postoperative pain treatment, and management of the complex patient with cardiac disease. - Includes expanded coverage of critical care topics, reflecting the increased perioperative care now provided by anesthesiologists in the ICU. - Contains new chapters on Structural Heart Disease Procedures; Cardiorespiratory Effects of COVID-19; Critical Care Ultrasound; Intensive Unit Management of Patients on Mechanical Circulatory Support; and Postoperative Care of the Heart and Lung Transplant Patient. - Features more than 900 full-color illustrations, decision trees, charts, and graphs (over one-third are new) that aid in visual understanding of complex topics. - Provides access to over 120 videos, including a range of echocardiography clips. - Contains balanced, dependable, and updated content on all aspects of the anesthetic management of cardiac surgical procedures, as well as cardiology procedures performed in catheterization and electrophysiologic laboratories. - Places new emphasis on cardiac devices requiring perioperative care, including cardiac implanted electrical devices and ventricular assist devices.
Design of Pulse Oximeters describes the hardware and software needed to make a pulse oximeter, and includes the equations, methods, and software required for them to function effectively. The book begins with a brief description of how oxygen is delivered to the tissue, historical methods for measuring oxygenation, and the invention of the pulse oximeter in the early 1980s. Subsequent chapters explain oxygen saturation display and how to use an LED, provide a survey of light sensors, and review probes and cables. The book closes with an assessment of techniques that may be used to analyze pulse oximeter performance and a brief overview of pulse oximetry applications. The book contains useful worked examples, several worked equations, flow charts, and examples of algorithms used to calculate oxygen saturation. It also includes a glossary of terms, instructional objectives by chapter, and references to further reading.
The value of echocardiography in the diagnostic work-up of patients with suspected acute pulmonary embolism.- New developments in the thrombolytic therapy of venous thrombosis.- Mechanism of blood coagulation. Newer aspects of anticoagulant and antithrombotic therapy.MR-angiography in the diagnosis of pulmonary embolism.Scintigraphy-ventilation/perfusion scanning and imaging of the embolus.- Clinical course and prognosis of acute pulmonary embolism.- The molecular mechanisms of inherited thombophilia.
Disturbances in peripheral O extraction can be produced in dogs treated with 2 endotoxin and thereby provide an opportunity to test theories for the origin of pathological O supply dependency or to try different treatment modalities. The 2 most serious deficiency in the current animal models is the inability to mimic the increased O demand that is observed in patients at 02 delivery rates in excess of 2 normal. A particular feature of this increased O demand is that it apparently does 2 not stimulate increased 02 extraction, although the limitation in O extraction has 2 not been explored in patients by lowering 02 supply, for obvious reasons. At least two possibilities to account for increased 02 demand could be investigated in animal models, however. The amount of 02 that is utilized in extramitochondrial pathways, which is normally on the order of 10%, may be greatly increased in ARDS and sepsis by O radical formation. There is presently no information 2 concerning how much 02 might be used in this way. Another strong possibility is that mitochondrial injury, perhaps as a result of 02 radical formation, uncouples oxidative phosphorylation. Some evidence presently in the literature supports this idea [19]. Indeed, the association of increased blood lactate levels with higher than expected 02 demands makes uncoupling a very attractive hypothesis that warrants further investigation in animal models using such agents as 2,4-dinitrophenol. References 1.
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.
Written and edited by renowned experts in pediatric anesthesia, Smith's Anesthesia for Infants and Children provides clear, concise guidance on effective perioperative care for any type of pediatric surgery. The 10th Edition contains significantly revised content throughout, bringing you fully up to date with recent advances in clinical and basic science that have led to changes in today's clinical practice. - Offers comprehensive coverage of physiology, pharmacology, and clinical anesthetic management of infants and children of all ages. - Contains new chapters on Airway Physiology and Development, Normal and Difficult Airway Management, Ultrasound, Acute Pain Management, Chronic Pain Management, Palliative Pain Management, Infectious Diseases, and Education; plus extensively revised content on cardiovascular physiology; induction, maintenance, and recovery; organ transplantation, and more. - Features more than 100 video demonstrations, including regional anesthesia videos, echocardiograms of congenital heart lesions, anatomic dissections of various congenital heart specimens with audio explanations, various pediatric surgical operative procedures, airway management, and much more. - Provides outstanding visual guidance throughout, including full-color photographs, drawings, graphs and charts, and radiographic images. - Includes quick-reference appendices online: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. - Provides an interactive question bank online for review and self-assessment. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
The Oxford Desk Reference: Critical Care allows easy access to evidence-based materials on commonly encountered critical care problems for quick consultation to ensure the optimum management of a particular condition. A concise reference book, it collates key recommendations and presents them in an easily accessible and uniform way.
This practical volume highlights traditional, novel, and evolving aspects of the diagnosis and treatment of pulmonary embolism (PE). The contributors comprise an international team of experts. Important aspects of diagnosis, risk stratification, and differential treatment of patients with PE are presented in a concise, yet comprehensive manner. Emphasis is placed on specific issues related to PE, including pregnancy, cancer, thrombophilia, and air travel.