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The brainstem reticular formation is the archaic core of ascending and descending pathways connecting the brain with spinal cord. After the pioneer description of the activating role of the ascending reticular activating system by Moruzzi and Magoun in 1949, an increasing number of studies have contributed to disclose the multifaceted roles of this brain area. In fact, the brainstem reticular formation sub-serves a variety of brain activities such as the modulation of the sleep-waking cycle, the level of arousal and attention, the drive for novelty seeking behaviors and mood. Meanwhile, descending pathways play a key role in posture modulation, extrapyramidal movements, and autonomic functions such as breathing and blood pressure. Moreover, both descending and ascending fibers of the reticular formation are critical in gating the sensory inputs and play a critical role in pain modulation and gaze control. All these activities are impaired when a damage affects critical nuclei of the reticular formation. Remarkably, in neurodegenerative diseases involving reticular nuclei, the rich collaterals interconnecting reticular isodendritic neurons represent a gateway for disease spreading placing the role of the reticular nuclei as a pivot in a variety of brain disorders. The present Research Topic is an updated collection of recent studies, which contribute to define the systematic anatomy of the reticular formation, its physiological and pharmacological features, as well as its involvement in neurodegenerative disorders and neuroprotection.
This volume in the Progress in Brain Research series features reviews on the functional neuroanatomy and connectivity of the brain areas involved in controlling eye movements. Oculomotor control of the eyes is now the subject of many research projects and advances in this field are relevant to understanding motor control in general.
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
This book is primarily designed for undergraduate medical and dental students. Also, it is an authoritative reference source for postgraduates and practicing neurologists and neurosurgeons. All chapters revised and updated, including details on cranial nerves and their lesions, blood supply and cerebrovascular accidents, motor and sensory disorders. new line diagrams, and real life photographs and MRI scans. Simple, to-the-point, easy-to-understand exam-oriented text Numerous, four coloured, large sized, and easy-to-draw diagrams Text provides unique problem based clinical and functional perspective
Newly revised and updated, A Textbook of Neuroanatomy, Second Edition is a concise text designed to help students easily master the anatomy and basic physiology of the nervous system. Accessible and clear, the book highlights interrelationships between systems, structures, and the rest of the body as the chapters move through the various regions of the brain. Building on the solid foundation of the first edition, A Textbook of Neuroanatomy now includes two new chapters on the brainstem and reflexes, as well as dozens of new micrographs illustrating key structures. Throughout the book the clinical relevance of the material is emphasized through clinical cases, questions, and follow-up discussions in each chapter, motivating students to learn the information. A companion website is also available, featuring study aids and artwork from the book as PowerPoint slides. A Textbook of Neuroanatomy, Second Edition is an invaluable resource for students of general, clinical and behavioral neuroscience and neuroanatomy.
Connections define the functions of neurons: information flows along connections, as well as growth factors and viruses, and even neuronal death can progress through connections. Accordingly, knowing how the various parts of the brain are interconnected to form functional systems is a prerequisite for properly understanding data from all fields in the neurosciences. Clinical Neuroanatomy: Brain Circuitry and Its Disorders bridges the gap between neuroanatomy and clinical neurology. It focuses on human and primate data in the context of brain circuitry disorders, which are so common in neurological practice. In addition, numerous clinical cases are presented to demonstrate how normal brain circuitry can be interrupted, and what the effects are. Following an introduction to the organization and vascularization of the human brain and the techniques used to study brain circuitry, the main neurofunctional systems are discussed, including the somatosensory, auditory, visual, motor, autonomic and limbic systems, the cerebral cortex and complex cerebral functions. In this 2nd edition, apart from a general updating, many new illustrations have been added and more emphasis is placed on modern techniques such as diffusion magnetic resonance imaging (dMRI) and network analysis. Moreover, a developmental ontology based on the prosomeric model is applied, resulting in a more modern subdivision of the brain. The new edition of Clinical Neuroanatomy is primarily intended for neurologists, neuroradiologists and neuropathologists, as well as residents in these fields, but will also appeal to (neuro)anatomists and all those whose work involves human brain mapping.
New edition building on the success of previous one. Retains core aim of providing an accessible introduction to behavioral neuroanatomy.
Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.
Fully updated and revised according to student feedback, the sixth edition of Mayo Clinic Medical Neurosciences: Organized by Neurologic System and Level provides a systematic approach to anatomy, physiology, and pathology of the nervous system inspired by the neurologist's approach to solving clinical problems. This volume has 4 sections: 1) an overview of the neurosciences necessary for understanding anatomical localization and pathophysiologic characterization of neurologic disorders; 2) an approach to localizing lesions in the 7 longitudinal systems of the nervous system; 3) an approach to localizing lesions in the 4 horizontal levels of the nervous system; and 4) a collection of clinical problems. This book provides the neuroscience framework to support the neurologist in a clinical setting and is also a great resource for neurology and psychiatry board certifications. This is the perfect guide for all medical students and neurology, psychiatry, and physical medicine residents at early stages of training. New to This Edition - A chapter devoted to multiple-choice questions for self-assessment - Discussion of emerging concepts in molecular, cellular, and system neurosciences - New chapters on emotion and consciousness systems - Incorporation of new discoveries in neuroimaging and an appendix for tables of medications commonly used to treat neurologic disorders
Cranial nerves are involved in head and neck function, and processes such as eating, speech and facial expression. This clinically oriented survey of cranial nerve anatomy and function was written for students of medicine, dentistry and speech therapy, but will also be useful for postgraduate physicians and GPs, and specialists in head and neck healthcare (surgeons, dentists, speech therapists etc.). After an introductory section surveying cranial nerve organisation and tricky basics such as ganglia, nuclei and brain stem pathways, the nerves are considered in functional groups: (1) for chewing and facial sensation; (2) for pharynx and larynx, swallowing and phonation; (3) autonomic components, taste and smell; (4) vision and eye movements; and (5) hearing and balance. In each chapter, the main anatomical features of each nerve are followed by clinical aspects and details of clinical testing. Simple line diagrams accompany the text. Detailed anatomy is not given.