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The compelling true story of Dr. Jonas Salk's quest to develop a vaccine for polio. In 1916, the United States was hit with one of the worst polio epidemics in history. The disease was a terrifying enigma: striking out of nowhere, it afflicted tens of thousands of children and left them—literally overnight—paralyzed. Others it simply killed. At the same time, a child named Jonas Salk was born.... When Franklin Delano Roosevelt was diagnosed with polio shortly before assuming the Presidency, Salk was given an impetus to study this deadly illness. After assisting in the creation of an influenza vaccine, Salk took up the challenge. His progress in combating the virus was hindered by the politics of medicine and by a rival researcher determined to discredit his proposed solution. But Salk's perseverance made history—and for close to seventy years his vaccine has saved countless lives, bringing humanity close to eradicating polio throughout the world. Splendid Solution chronicles Dr. Salk's race against time to achieve an unparalleled breakthrough that made him a cultural hero and icon of modern medicine.
Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.
NATIONAL BESTSELLER • Set in a close-knit Newark neighborhood during a terrifying polio outbreak in 1944, a “book [that] has the elegance of a fable and the tragic inevitability of a Greek drama” (The New Yorker)—from the Pulitzer Prize–winning author of American Pastoral. Bucky Cantor is a vigorous, dutiful twenty-three-year-old playground director during the summer of 1944. A javelin thrower and weightlifter, he is disappointed with himself because his weak eyes have excluded him from serving in the war alongside his contemporaries. As the devastating disease begins to ravage Bucky’s playground, Roth leads us through every inch of emotion such a pestilence can breed: fear, panic, anger, bewilderment, suffering, and pain. Moving between the streets of Newark and a pristine summer camp high in the Poconos, Nemesis tenderly and startlingly depicts Cantor’s passage into personal disaster, the condition of childhood, and the painful effect that the wartime polio epidemic has on a closely-knit, family-oriented Newark community and its children.
Dirt and Disease is a social, cultural, and medical history of the polio epidemic in the United States. Naomi Rogers focuses on the early years from 1900 to 1920, and continues the story to the present. She explores how scientists, physicians, patients, and their families explained the appearance and spread of polio and how they tried to cope with it. Rogers frames this study of polio within a set of larger questions about health and disease in twentieth-century American culture.
In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.
Here, from James Tobin, winner of the National Book Critics Circle Award in biography, is the story of the greatest comeback in American political history, a saga long buried in half-truth, distortion, and myth—Franklin Roosevelt’s ten-year climb from paralysis to the White House. In 1921, at the age of thirty-nine, Roosevelt was the brightest young star in the Democratic Party. One day he was racing his children around their summer home. Two days later he could not stand up. Hopes of a quick recovery faded fast. “He’s through,” said allies and enemies alike. Even his family and close friends misjudged their man, as they and the nation would learn in time. With a painstaking reexamination of original documents, James Tobin uncovers the twisted chain of accidents that left FDR paralyzed; he reveals how polio recast Roosevelt’s fateful partnership with his wife, Eleanor; and he shows that FDR’s true victory was not over paralysis but over the ancient stigma attached to the disabled. Tobin also explodes the conventional wisdom of recent years—that FDR deceived the public about his condition. In fact, Roosevelt and his chief aide, Louis Howe, understood that only by displaying himself as a man who had come back from a knockout punch could FDR erase the perception that had followed him from childhood—that he was a pampered, too smooth pretty boy without the strength to lead the nation. As Tobin persuasively argues, FDR became president less in spite of polio than because of polio. The Man He Became affirms that true character emerges only in crisis and that in the shaping of this great American leader character was all.
The story of mankind's struggle against polio is compelling, exciting and full of twists and pardoxes. One of the grand challenges of modern medicine, it was a battleground between good and bad science. Gareth Williams takes an original view of the journey to understanding and defeating polio.
Jonas Salk's polio vaccine has taken on an almost legendary quality as a medical miracle, for it largely eradicated one of the most feared diseases of the 20th century. But the story of the vaccine has a dark side, one that has never been fully told before... Between 1954 and 1963, close to 98 million Americans received polio vaccinations contaminated with a carcinogenic monkey virus, now known as SV40. A concerted government effort downplayed the incident, and it was generally accepted that although oncogenic to laboratory animals, SV40 was harmless to humans. But now SV40 in showing up in human cancers, and prominent researchers are demanding a serious public health response to this forgotten polio vaccine contaminant. A gripping medical detective story, The Virus and the Vaccine raises major questions about vaccine policy.
Poliomyelitis, better known as polio, thoroughly stumped the medical science community. Polio's impact remained highly visible and sometimes lingered, exacting a priceless physical toll on its young victims and their families as well as transforming their social worlds. This social history of infantile paralysis is plugged into the rich and dynamic developments of the United States during the first half of the twentieth century. Children became epidemic refugees because of anachronistic public health policies and practices. They entered the emerging, clinical world of the hospital, rupturing physical and emotional connections with their parents and siblings. As they underwent rehabilitation, they created ward cultures. They returned home to occasionally find hostile environments and always discover changed relationships due to their disabilities. The changing concept of the child, from an economic asset to an emotional commitment, medical advances, and improved sanitation policies led to significant improvements in child health and welfare. This study, relying on published autobiographies, memoirs, and oral histories, captures the impact of this disease on children's personal lives, encompassing public-health policies, hospitalization, philanthropic and organizational responses, physical therapy, family life, and schooling. It captures the anger, frustration, and terror not only among children but parents, neighbors, and medical professionals alike.
Based on thousands of hours of research, this companion book to the PBS documentary of the same name tells the story of the polio epidemic in America. 100 photos.