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This is a critical assessment of breakthrough biosensor technologies that will allow for the rapid identification of biological threat agents in the environment and human population. The book provides a comprehensive overview of the current state of biological weapons threat, and reviews biosensor technologies including detection platforms, networked alarm-type biodetector systems, implementation strategies, electro-optical and electrochemical biosensors.
A bioaerosol is a colloidal suspension of liquid droplets or solid particles in air whose components contain or have attached to them one or more microorganisms. Bioaerosols are an exciting and vital object of study because the attached microbes play a critical role in human, animal and environmental health. In an era of genetically engineered microorganisms and the application of biopesticides, bioaerosols are increasingly an environmental problem, both indoors and outdoors, and can affect entire ecosystems. Atmospheric Microbial Aerosols examines naturally occuring bioaerosols, as well as bioaerosols generated by human activity. Included in this volume is a complete array of topics concerned with outdoor microbial bioaerosols ranging from the physical and chemical to the meteorological and microbial. It will be of great interest as a starting point for researchers interested in outdoor microbial bioaerosols as well as for those interested in atmospheric dispersion models, new equipment, and government regulations.
This book is intended to give technological background and practical examples, but also to give general insight into the on-going technology development in the area of biodetection. The content is therefore suitable for an array of stakeholders (decision makers, purchasing officers, etc.) and end-users of biodetection equipment within the areas of health, environment, safety and security, and military preparation. The book is divided into three sections. The first section discusses the fundamental physical and biological properties of bioaerosol's. The second section goes into more detail and discusses in-depth the most commonly used detection principles. The third section of the book is devoted to technologies that have been used in standoff applications. The last section of the book gives an overview of trends in bioaerosol detection. The reader of this book will gain knowledge about the different biodetection technologies and thus better judge their capabilities in relation to desired applications.
Over the last ten years, there has been growing concern about potential biological attacks on the nation's population and its military facilities. It is now possible to detect such attacks quickly enough to permit treatment of potential victims prior to the onset of symptoms. The capability to "detect to warn", that is in time to take action to minimize human exposure, however, is still lacking. To help achieve such a capability, the Defense Threat Reduction Agency (DTRA) asked the National Research Council (NRC) to assess the development path for "detect to warn" sensors systems. This report presents the results of this assessment including analysis of scenarios for protecting facilities, sensor requirements, and detection technologies and systems. Findings and recommendations are provided for the most probable path to achieve a detect-to-warn capability and potential technological breakthroughs that could accelerate its attainment.
This comprehensive handbook provides up-to-date knowledge and practical advice from established authorities in aerosol science. It covers the principles and practices of bioaerosol sampling, descriptions and comparisons of bioaerosol samplers, calibration methods, and assay techniques, with an emphasis on practicalities, such as which sampler to use and where it should be placed. The text also offers critiques concerning handling the samples to provide representative and meaningful assays for their viability, infectivity, and allergenicity. A wide range of microbes-viz., viruses, bacteria, fungi and pollens, and their fragments-are considered from such perspectives. Bioaerosols Handbook is divided into four parts, providing a wide-ranging reference work, as well as a practical guide on how best to sample and assay bioaerosols using current technology.
The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.
This Annual Report of the Department of Defense (DoD) Chemical, Biological, Radiological, and Nuclear (CBRN) Defense Program, or CBRNDP, provides information in response to several reporting requirements. First, this report is provided in accordance with 50 USC 1523. (The complete reporting requirement is detailed at annex K.) This report is intended to assess: (1) the overall readiness of the Armed Forces to fight in a chemical-biological warfare environment and steps taken and planned to be taken to improve such readiness; and, (2) requirements for the chemical and biological warfare defense program, including requirements for training, detection, and protective equipment, for medical prophylaxis, and for treatment of casualties resulting from use of chemical and biological weapons. This report supplements the DoD Chemical and Biological Defense Program FY05 President's budget, February 2004, which has been submitted to Congress.