Download Free The Cutter Incident Book in PDF and EPUB Free Download. You can read online The Cutter Incident and write the review.

Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.
"A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing notions of health, risk, and the common good.
The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.
Understand the Virus -- Explore the Immune System -- Discover a Vaccine -- Develop Vaccines -- Evaluate the Contenders -- Don't Count on the Magic Bullet -- Overcome the Hurdles -- Embrace Many Solutions.
Through the lens of polio, Dóra Vargha looks anew at international health, communism and Cold War politics. This title is also available as Open Access.
In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.
The first full biography of Jonas Salk offers a complete picture of the enigmatic figure, from his early years working on an influenza vaccine--for which he never fully got credit--to his seminal creation of the Polio vaccine, up through his later work to find a cure for AIDS.
The Oxford Textbook of Infectious Disease Control: A Geographical Analysis from Medieval Quarantine to Global Eradication is a comprehensive analysis of spatial theory and the practical methods used to prevent the geographical spread of communicable diseases in humans. Drawing on current and historical examples spanning seven centuries from across the globe, this indispensable volume demonstrates how to mitigate the public health impact of infections in disease hotspots and prevent the propagation of infection from such hotspots into other geographical locations. Containing case studies of longstanding global killers such as influenza, measles and poliomyelitis, through to newly emerged diseases like SARS and highly pathogenic avian influenza in humans, this book integrates theory, data and spatial analysis and locates these quantitative analyses in the context of global demographic and health policy change. Beautifully illustrated with over 100 original maps and diagrams to aid understanding and assimilation, in six sections the authors examine surveillance, quarantine, vaccination, and forecasting for disease control. The discussion covers theoretical approaches, techniques and systems central to mitigating disease spread, and methods that deliver practical disease control. Essential information is also provided on the geographical eradication of diseases, including the design of early warning systems that detect the geographical spread of epidemics, enabling students and practitioners to design spatially-targeted control strategies. Despite the early hope of eradication of many communicable diseases after the global eradication of smallpox by 1979, the world is still working at the control and elimination of the spatial spread of newly-emerging and resurgent infectious diseases. Learning from past examples and incorporating modern surveillance and reporting techniques that are used to design value-for-money spatially-targeted interventions to protect public health, the Oxford Textbook of Infectious Disease Control is an essential resource for all those working in, or studying ways to control the spread of communicable diseases between humans in a timely and cost-effective manner. It is ideal for specialists and students in infectious disease control as well as those in the medical sciences, epidemiology, demography, public health, geography, and medical history.
A “clear and insightful” takedown of the anti-vaccination movement, from its 19th-century antecedents to modern-day Facebook activists—with strategies for refuting false claims of friends and family (Financial Times) Vaccines are a documented success story, one of the most successful public health interventions in history. Yet there is a vocal anti-vaccination movement, featuring celebrity activists (including Kennedy scion Robert F. Kennedy Jr. and actress Jenny McCarthy) and the propagation of anti-vax claims through books, documentaries, and social media. In Anti-Vaxxers, Jonathan Berman explores the phenomenon of the anti-vaccination movement, recounting its history from its nineteenth-century antecedents to today’s activism, examining its claims, and suggesting a strategy for countering them. After providing background information on vaccines and how they work, Berman describes resistance to Britain’s Vaccination Act of 1853, showing that the arguments anticipate those made by today’s anti-vaxxers. He discusses the development of new vaccines in the twentieth century, including those protecting against polio and MMR (measles, mumps, rubella), and the debunked paper that linked the MMR vaccine to autism; the CDC conspiracy theory promoted in the documentary Vaxxed; recommendations for an alternative vaccination schedule; Kennedy’s misinformed campaign against thimerosal; and the much-abused religious exemption to vaccination. Anti-vaxxers have changed their minds, but rarely because someone has given them a list of facts. Berman argues that anti-vaccination activism is tied closely to how people see themselves as parents and community members. Effective pro-vaccination efforts should emphasize these cultural aspects rather than battling social media posts.