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This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, since it is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting-ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is intended to provide the conceptual basis for a comprehen sive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of devel opmental biology should understand the experimental background of the field and be able to place that body of information in context to ascertain where additional research would be fruitful. At that point, the creative process gener ates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery.
This book covers recent trends in the study of cell surfaces, cell interactions, and cell behavior during selected events in development and cancer. It relates current thrusts in molecular biology to more cellular aspects of these fields and draws parallels between advances in developmental biology, malignant invasiveness, wound healing, and regeneration. The book opens with a discussion of a number of developmental events, stressing the importance of the cell surface and extracellular matrix to morphogenesis, cell locomotion, and invasiveness. Basement membranes are discussed in terms of their activity as substrata for cell movement, barriers to invasion, and their role in epithelial-mesenchymal interactions. These aspects of cell-cell and cell-matrix interaction are directly compared with developmental and neoplastic events, emphasizing the epithelial-to-mesenchymal transformations that are common to both of these situations. Other topics discussed include cell surface considerations, cell-cell adhesion, cell-substratum adhesion, as well as a discussion regarding how these topics are relevant to the cell biology of wound healing and regeneration. This book is ideal for researchers and students in biology, cell biology, biochemistry, molecular biology, anatomy, zoology, and medicine.
This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, which is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is comprised of chapters selected to provide the conceptual basis for a comprehensive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of developmental biology should understand the experimental back ground of the specialty and be able to place that body of information in context, in order to ascertain where additional research would be fruitful. The creative process then generates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery.
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
The Biology of the Cell Surface is a book by American biologist Ernest Everett Just. It was published by P. Blakiston's Son & Co in 1939. Just began writing the book in 1934 in Naples and finished it in France, shortly before being sent to a prisoner-of-war camp. He considered the book to be his "crowning achievement". The book examined the role of the cell surface in embryology, development and evolution, and presented a critique of gene theory, particularly the views of Jacques Loeb. Sapp suggests that "Just's theorizing on the cell cortex [in this work] was unsurpassed."