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Follow along as this New York Times bestselling author details the astonishing scientific discovery of the code to unleashing the human immune system to fight in this "captivating and heartbreaking" book (The Wall Street Journal). For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses -- tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In The Breakthrough, New York Times bestselling author of The Good Nurse Charles Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step -- harnessing the wealth of new information to create modern and more effective patient therapies -- is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history.
The Impossible reveals prayer's immediate and powerful impact through the true account of a family whose son died and was miraculously resurrected. Through the years and the struggles, when life seemed more about hurt and loss than hope and mercy, God was positioning the Smiths for something extraordinary-the death and resurrection of their son. When Joyce Smith's fourteen-year-old son John fell through an icy Missouri lake one winter morning, she and her family had seemingly lost everything. At the hospital, John lay lifeless for more than sixty minutes. But Joyce was not ready to give up on her son. She mustered all her faith and strength into one force and cried out to God in a loud voice to save him. Miraculously, her son's heart immediately started beating again. In the coming days, John would defy every expert, every case history, and every scientific prediction. Sixteen days after falling through the ice and being clinically dead for an hour, he walked out of the hospital under his own power, completely healed. The Impossible is about a profound truth: prayer really does work. God uses it to remind us that He is always with us, and when we combine it with unshakable faith, nothing is impossible.
Breakthrough: Trusting God for Big Change in Your Church encourages leaders of churches that are struggling and wondering if it's time to close the doors on God's work through them, their family, their church, or their ministry. This book is especially for those who have the audacity to dare to imagine where a new window might open as an old door is closing. Breakthrough reveals gritty, well-grounded hope around every corner.
In The Breakthrough, veteran journalist Gwen Ifill surveys the American political landscape, shedding new light on the impact of Barack Obama’s stunning presidential victory and introducing the emerging young African American politicians forging a bold new path to political power. Ifill argues that the Black political structure formed during the Civil Rights movement is giving way to a generation of men and women who are the direct beneficiaries of the struggles of the 1960s. She offers incisive, detailed profiles of such prominent leaders as Newark Mayor Cory Booker, Massachusetts Governor Deval Patrick, and U.S. Congressman Artur Davis of Alabama (all interviewed for this book), and also covers numerous up-and-coming figures from across the nation. Drawing on exclusive interviews with power brokers such as President Obama, former Secretary of State Colin Powell, Vernon Jordan, the Reverend Jesse Jackson, his son Congressman Jesse Jackson Jr., and many others, as well as her own razor-sharp observations and analysis of such issues as generational conflict, the race/ gender clash, and the "black enough" conundrum, Ifill shows why this is a pivotal moment in American history. The Breakthrough is a remarkable look at contemporary politics and an essential foundation for understanding the future of American democracy in the age of Obama.
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"A clear and insightful look at why teaching must be conceived as constant learning about learning. The analysis of past failed reforms and the general conditions needed for success is well-stated and illuminating." —Grant Wiggins Authentic Education Redesign classroom instruction to transform learning for both students and teachers! Breakthrough presents a revolutionary new approach to educational reform, breaking away from the conventional paradigm to help educators create focused instruction, transform the classroom experience, and dramatically raise—and sustain—performance levels for students and teachers alike. This book provides the breakthrough concepts needed for developing precise, validated, data-driven instruction personalized to each and every student. Synthesizing the best of current instructional models, this framework focuses on the components of the Triple P Breakthrough Model: Personalization—meaningful, student-centered classroom interactions; Precision—using formative assessments to monitor individual student progress; and Professional Learning—daily, ongoing learning for all educators. Helping educators create expert instructional systems while breaking through the "prescription trap," the authors introduce unique elements of the Breakthrough model, including: Improvement by design Assessment for learning Critical learning instructional paths Mapping instructional paths Smart use of data to drive instruction Locking in ongoing improvement Breakthrough establishes the tipping point for moving toward personalized, high-quality instruction and learning in the classroom to ensure continuous improvement and ongoing academic success.
In The Breakthrough Company, Keith McFarland pinpoints how everyday companies become extraordinary, showing that luck is a negligible factor. Rather, breakthrough success turns out to be associated with a clearly identifiable set of strategies and skills that anyone in any business can emulate - from small startup to industry paragon. Encouraged by experts such as business legend Peter Drucker and Good to Great author Jim Collins to identify the drivers that enable a company to push past the entrepreneurial phase, McFarland spent five years building and analyzing the world's largest growth-company performance database and interviewing more than 1,500 growth-company executives on four continents. His goal was simple: to identify the secrets of breakthrough. This book is the result. Winnowing a study pool of more than 7,000 companies down to nine that have made the transition to major-player status, McFarland highlights real-world tools and myth-busting insights that can be used by anyone wanting his or her business to join this exclusive circle.
As an eleven-year-old girl living in Iran, Zahra’s live was forever changed after her father was killed instantly in a car accident. In this firsthand account, Zahra recounts her journey of personal growth and intimate relationship with God that ultimately gave her the strength to end her abusive twenty-three-year marriage. In this tale of self-growth, Zahra describes her daily struggles as a mother and a wife, and the spiritual transformation that led her to independence. From dealing with her father’s tragic death to her rushed marriage to a man she hardly knew, Zahra shares her intimate conversations with God and how he has been there every step of the way, to help guide her through the pain, tears, dark days, and ultimately to the joy she has found today. Her faith in God allowed her to find the courage to seek justice when she thought no one was out there and enabled her to end her destructive cycle of marriage. It inspired her to follow her dreams and led her to find her passion in life. The Breakthrough demonstrates the power of God and the inspiration that can be found among those who believe in him.
Deliver innovative results like clockwork with this repeatable formula for creativity-on-demand Have you ever sat down at your desk with an impossible deadline or an insurmountable obstacle staring you directly in the face and an expectation that you’ll come up with a groundbreaking idea and solution? In Breakthrough, you’ll find a powerful framework for bringing innovation and creativity to the surface not just once, but on a regular, daily basis. In Breakthrough, bestselling author, acclaimed speaker, and life optimization coach David Nurse provides an actionable and clearly organized structure for maximizing your breakthrough ideas. Breakthrough outlines easy-to-follow steps for outperforming your potential: An accessible blueprint—backed by scientific data and years of case studies with the top athletes, entrepreneurial minds, and leaders throughout the world—to unlocking your creative potential Conclusive proof that busts the myths of the lone genius, unpredictable ‘a-ha’ lightbulb moments, and little happy accidents Ways to promote an environment and mindset in which groundbreaking new ideas can flow and occur naturally and seamlessly based on a repeatable formula A must-read for any athlete, manager, executive, or parent tasked with delivering dynamic results in a flash, Breakthrough also belongs on the bookshelves of product design professionals, marketers, and other creative types who seek to consistently exceed expectations. Breakthrough is not about going from good to great; it’s about going from great to outstanding!