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Teratoid Heights realistically depicts the lifecycles of various species found in the tide location's cave-riddled terrain, down to the most painstakingly detailed behavioral patterns. It matters not that both Teratoid Heights and its inhabitants are entirely fictional. Brinkman taps into the zeitgeist of modern suburban America with what seems to be a mixture of J.R.R. Tolkein-style adventure, video-game inspired syncopation and an endless barrage of cable-television nature films all filtered through the reddened eyes of a marijuana-addled teenager. A book that reveals levels of humor and humanity no matter what age the reader.
The first chapter in a grand fantasy epic filled with psychic warrior monks, magic battles, monsters, and romance from the mind of Zack Soto!
Since the 2011 release of Goliath, Tom Gauld has solidified himself as one of the world’s most revered and critically-acclaimed cartoonists working today. From his weekly strips in the Guardian and New Scientist, to his lauded graphic novels You're All Just Jealous of My Jetpack and Mooncop, Gauld’s fascination with the intersection between history, literary criticism, and pop culture has become the crux of his work. Now in paperback, with a new cover and smaller size, Goliath is a retelling of the classic myth, this time from Goliath's side of the Valley of Elah. Goliath of Gath isn't much of a fighter. He would pick admin work over patrolling in a heartbeat, to say nothing of his distaste for engaging in combat. Nonetheless, at the behest of the king, he finds himself issuing a twice-daily challenge to the Israelites: "Choose a man. Let him come to me that we may fight." Quiet moments in Goliath's life as an isolated soldier are accentuated by Gauld's trademark drawing style: minimalist scenery, geometric humans, and densely crosshatched detail. Simultaneously tragic and bleakly funny, Goliath displays a sensitive wit and a bold line--a traditional narrative reworked, remade, and revolutionized into a classic tale of Gauld’s very own.
Many of the earliest books, particularly those dating back to the 1900s and before, are now extremely scarce and increasingly expensive. We are republishing these classic works in affordable, high quality, modern editions, using the original text and artwork.
Features 300 of Tim Goodyear's movie reviews with hand drawn recreations of the movie's original advertising or VHS box art.
The pediatric head and neck cancer patient necessitates a multidisciplinary team of specialists to provide an optimal continuum of care. This A-Z guide provides practical, in-depth information for all medical professionals involved in the evaluation and treatment of these patients. Written in an easy to follow format, each entry contains illustrative figures to aid in pathological and radiographical diagnosis, as well as structured discussion of evaluation and multimodality management. The alphabetical layout eliminates redundancy and allows the busy physician to quickly locate relevant information. Pediatric Head and Neck Tumors is ideal for young physicians as well as attending physicians seeking to expand their knowledgebase to the various subspecialties involved in the multidisciplinary care of their patients.
This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. - Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications - Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America - Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs
Knowledge about the etiology and diagnosis as well as treatment concepts of neu- oncologic diseases is rapidly growing. This turnover of knowledge makes it dif? cult for the physician engaged in the treatment to keep up to date with current therapies. This book sets out to close the gap and pursues several innovative concepts. As a comprehensive text on neuro-oncology, its chapters are interconnected, but at the same time some chapters or subdivisions are so thoroughly assembled that the whole volume gives the impression of several books combined into one. Neuropathology is treated in an extensive and clearly structured section. The int- ested reader ? nds for each tumor entity the latest well-referenced consensus rega- ing histologic and molecular pathology. Through this “book-in-the-book” concept, information on neuropathology is readily at hand in a concise form and without ov- loading the single chapters. Pediatric neuro-oncology differs in many entities from tumors in adult patients; also, certain tumors of the CNS are typically or mainly found only in the child. Therefore, pediatric neuro-oncology was granted its own, book-like section. Tumor entities that are treated differently in children and adults are included both in the pediatric neuro-oncology section and in the general section. Entities that typically occur only in the child and adolescent are found in the pediatric section in order to avoid redundancies.
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings. In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders. Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field. The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms. - Introduces the genetic and non-genetic causes of autism and associated intellectual disabilities - Describes the genes implicated in autistic spectrum disorders and their function - Considers major individual genetic causes of autism, Rett syndrome, Fragile X syndrome, and other autism spectrum disorders, as well as their classification as synaptopathies - Presents a thorough discussion of the clinical aspects of multiple neurodevelopmental disorders and the experimental models that exist to study their pathophysiology in vitro and in vivo, including animal models and patient-derived stem cell culture