Download Free Technetium Book in PDF and EPUB Free Download. You can read online Technetium and write the review.

Dieses einzigartige Handbuch gibt eine umfassende Übersicht über den aktuellen Stand der Technetium-Chemie und die Anwendung von Technetium in der Radiopharmazie. Klar und präzise dargestellt werden alle wichtigen Aspekte wie · natürliches und künstlich verursachtes Vorkommen in der Umwelt, · Isotope und Isomere, · Analytische Chemie und Biochemie, · thermodynamische Daten, Stabilität und Reaktivität, · intermetallische und binäre Verbindungen, und vor allem · Komplexchemie sowie · radiopharmazeutischer Einsatz. Dieses herausragende Werk erlaubt sowohl Experten als auch Laien mit naturwissenschaftlicher Bildung einen schnellen Zugang zu wichtiger Information. Deshalb ist das Handbuch genauso unverzichtbar für Forscher an Universitäten und Instituten, in der Nuklearmedizin und radiopharmazeutischen Industrie wie für wissenschaftliche Berater in Regierungen und Umweltverbänden.
Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.
This book is the product of a congressionally mandated study to examine the feasibility of eliminating the use of highly enriched uranium (HEU2) in reactor fuel, reactor targets, and medical isotope production facilities. The book focuses primarily on the use of HEU for the production of the medical isotope molybdenum-99 (Mo-99), whose decay product, technetium-99m3 (Tc-99m), is used in the majority of medical diagnostic imaging procedures in the United States, and secondarily on the use of HEU for research and test reactor fuel. The supply of Mo-99 in the U.S. is likely to be unreliable until newer production sources come online. The reliability of the current supply system is an important medical isotope concern; this book concludes that achieving a cost difference of less than 10 percent in facilities that will need to convert from HEU- to LEU-based Mo-99 production is much less important than is reliability of supply.
The decay product of the medical isotope molybdenum-99 (Mo-99), technetium-99m (Tc-99m), and associated medical isotopes iodine-131 (I-131) and xenon-133 (Xe-133) are used worldwide for medical diagnostic imaging or therapy. The United States consumes about half of the world's supply of Mo-99, but there has been no domestic (i.e., U.S.-based) production of this isotope since the late 1980s. The United States imports Mo-99 for domestic use from Australia, Canada, Europe, and South Africa. Mo-99 and Tc-99m cannot be stockpiled for use because of their short half-lives. Consequently, they must be routinely produced and delivered to medical imaging centers. Almost all Mo-99 for medical use is produced by irradiating highly enriched uranium (HEU) targets in research reactors, several of which are over 50 years old and are approaching the end of their operating lives. Unanticipated and extended shutdowns of some of these old reactors have resulted in severe Mo-99 supply shortages in the United States and other countries. Some of these shortages have disrupted the delivery of medical care. Molybdenum-99 for Medical Imaging examines the production and utilization of Mo-99 and associated medical isotopes, and provides recommendations for medical use.
Since the discovery of technetium (in 1937, by Perrier and Segre), technetium-99 and technetium-99m have become most familiar in the specialised literature, the behaviour of the former being of concern regarding its health impact, the latter having been used intensively in medical tests for many years. The knowledge of the characteristics and behaviour of this element in nature is currently increasing exponentially. It has become clear, however, that there is still a serious shortage of information needed to assess properly its burden and impact on man and his environment. Technetium may indeed be released from nuclear installations or as a waste product from medical applications. It is generally considered to be highly mobile as the anion TcOi, but it is also suspected to be readily reduced in soils and metabolised in living beings into lower oxidation states. The seminar was planned to analyse thoroughly the experimental results obtained up to now and to make recommendations of specific issues requiring further research. This book presents the papers of the different sessions in the order of presentation, and the conclusions drawn by three discussion groups which dealt separately with: problems of sources and distribution of man-made technetium and its radiological consequences; the chemical behaviour of technetium in different ecosystems; biochemical reactions and binding with macromolecules in various life systems. vi Preface The editors, together with the Programme Committee of the Seminar, wish to express their gratitude to the chairmen of the different sessions for their summary of the group discussions.
Participants of the July 17-18, 2017, symposium titled Opportunities and Approaches for Supplying Molybdenum-99 and Associated Medical Isotopes to Global Markets examined current trends in molybdenum-99 production, prospects for new global supplies, and technical, economic, regulatory, and other considerations for supplying molybdenum-99 to global markets. This publication summarizes the presentations and discussions from the symposium.
Since the discovery of technetium (in 1937, by Perrier and Segre), technetium-99 and technetium-99m have become most familiar in the specialised literature, the behaviour of the former being of concern regarding its health impact, the latter having been used intensively in medical tests for many years. The knowledge of the characteristics and behaviour of this element in nature is currently increasing exponentially. It has become clear, however, that there is still a serious shortage of information needed to assess properly its burden and impact on man and his environment. Technetium may indeed be released from nuclear installations or as a waste product from medical applications. It is generally considered to be highly mobile as the anion TcOi, but it is also suspected to be readily reduced in soils and metabolised in living beings into lower oxidation states. The seminar was planned to analyse thoroughly the experimental results obtained up to now and to make recommendations of specific issues requiring further research. This book presents the papers of the different sessions in the order of presentation, and the conclusions drawn by three discussion groups which dealt separately with: problems of sources and distribution of man-made technetium and its radiological consequences; the chemical behaviour of technetium in different ecosystems; biochemical reactions and binding with macromolecules in various life systems. vi Preface The editors, together with the Programme Committee of the Seminar, wish to express their gratitude to the chairmen of the different sessions for their summary of the group discussions.
This volume in the series Chemical Thermodynamics provides a comprehensive review and critical evaluation of experimental data available for the chemical thermodynamics of inorganic compounds and aqueous species and complexes of technetium. The objective of the reviews in the series Chemical Thermodynamics is to provide a set of reliable thermodynamic data that can be used to describe the behaviour of the elements reviewed under conditions relevant for radioactive waste disposal systems and various geochemical environments. Data and their uncertainty limits are recommended for the formation energies, enthalpies and entropies of selected aqueous complexes, solids and gaseous compounds containing technetium. The data are internally consistent and compatible with the CODATA Key Values, as well as with the data in the earlier volumes in the series Chemical Thermodynamics. The book contains a detailed discussion of the selection procedures used
1635 references to journal articles and reports. Also includes foreign literature. Arranged in numerical sequence. Entries include bibliographical information and keywords. Author index, Permuted index of significant words (in the titles).
This book provides detailed information on the electrochemistry of technetium compounds. After a brief physico-chemical characterization of this element, it presents the comparative chemistry of technetium, manganese and rhenium. Particular attention is paid to the stability, disproportionation, comproportionation, hydrolysis and polymerization reactions of technetium ions and their influence on the observed redox systems. The electrochemical properties of both inorganic as well as organic technetium species in aqueous and non-aqueous solutions are also discussed. The respective chapters cover the whole spectrum of topics related to the application of technetium in nuclear medicine, electrochemistry of technetium in spent nuclear fuel (including corrosion properties of technetium alloys), and detecting trace amounts of technetium with the aid of electrochemical methods. Providing readers with information not easily obtained in any other single source, the book will appeal to researchers working in nuclear chemistry, nuclear medicine or the nuclear industry.