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Prions and Neurodegenerative Diseases, Volume 172, in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Cell-free amplification of prions: where do we stand? Transgenic mouse models for the study of prion diseases and much more. - Includes comprehensive coverage of molecular biology - Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided - Contains contributions from renowned experts in the field - Includes comprehensive coverage of molecular biology - Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided - Contains contributions from renowned experts in the field
This volume provides a collection of research reports on multilingualism and language contact ranging from Romance, to Germanic, Greco and Slavic languages in situations of contact and diaspora. Most of the contributions are empirically-oriented studies presenting first-hand data based on original fieldwork, and a few focus directly on the methodological issues in such research. Owing to the multifaceted nature of contact and diaspora phenomena (e.g. the intrinsic transnational essence of contact and diaspora, and the associated interplay between majority and minoritized languages and multilingual practices in different contact settings, contact-induced language change, and issues relating to convergence) the disciplinary scope is broad, and includes ethnography, qualitative and quantitative sociolinguistics, formal linguistics, descriptive linguistics, contact linguistics, historical linguistics, and language acquisition. Case studies are drawn from Italo-Romance varieties in the Americas, Spanish-Nahuatl contact, Castellano Andino, Greko/Griko in Southern Italy, Yiddish in Anglophone communities, Frisian in the Netherlands, Wymysiöryś in Poland, Sorbian in Germany, and Pomeranian and Zeelandic Flemish in Brazil.
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The term “reactive oxygen species” (ROS) refers to a group of reactive molecules and free radicals produced by molecular oxygen. In recent decades, there has been great interest in the role of ROS in various diseases. From basic science research to clinical trials, biomedical scientists have made rapid progress toward a better understanding of ROS-metabolizing systems and their role in health and diseases. This book includes sixteen chapters that address topics such as the history of ROS, its role in autoimmunity, neurodegeneration, and aging, and recent advances in various antioxidants and their therapeutic potential.