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This two-volume work provides an overview on various state of the art experimental and statistical methods, modeling approaches and software tools that are available to generate, integrate and analyze multi-omics datasets in order to detect biomarkers, genetic markers and potential causal genes for improved animal production and health. The book will contain online resources where additional data and programs can be accessed. Some chapters also come with computer programming codes and example datasets to provide readers hands-on (computer) exercises. This first volume presents the basic principles and concepts of systems biology with theoretical foundations including genetic, co-expression and metabolic networks. It will introduce to multi omics components of systems biology from genomics, through transcriptomics, proteomics to metabolomics. In addition it will highlight statistical methods and (bioinformatic) tools available to model and analyse these data sets along with phenotypes in animal production and health. This book is suitable for both students and teachers in animal sciences and veterinary medicine as well as to researchers in this discipline.
This two-volume work provides an overview on various state of the art experimental and statistical methods, modeling approaches and software tools that are available to generate, integrate and analyze multi-omics datasets in order to detect biomarkers, genetic markers and potential causal genes for improved animal production and health. The book will contain online resources where additional data and programs can be accessed. Some chapters also come with computer programming codes and example datasets to provide readers hands-on (computer) exercises. This second volume deals with integrated modeling and analyses of multi-omics datasets from theoretical and computational approaches and presents their applications in animal production and health as well as veterinary medicine to improve diagnosis, prevention and treatment of animal diseases. This book is suitable for both students and teachers in animal sciences and veterinary medicine as well as to researchers in this discipline.
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Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology. Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
This book provides an entry point into Systems Biology for researchers in genetics, molecular biology, cell biology, microbiology and biomedical science to understand the key concepts to expanding their work. Chapters organized around broader themes of Organelles and Organisms, Systems Properties of Biological Processes, Cellular Networks, and Systems Biology and Disease discuss the development of concepts, the current applications, and the future prospects. Emphasis is placed on concepts and insights into the multi-disciplinary nature of the field as well as the importance of systems biology in human biological research. Technology, being an extremely important aspect of scientific progress overall, and in the creation of new fields in particular, is discussed in 'boxes' within each chapter to relate to appropriate topics. - 2013 Honorable Mention for Single Volume Reference in Science from the Association of American Publishers' PROSE Awards - Emphasizes the interdisciplinary nature of systems biology with contributions from leaders in a variety of disciplines - Includes the latest research developments in human and animal models to assist with translational research - Presents biological and computational aspects of the science side-by-side to facilitate collaboration between computational and biological researchers
Biotechnology in Healthcare, Technologies and Innovations, Volume One presents up-to-date knowledge on the emerging field of biotechnology as applied to the healthcare industry. Sections cover 3D printing, tissue engineering, synthetic biology, nano-biotechnology, omics, precision medicine, gene therapy, vaccine development, predictive healthcare, entrepreneurship, financing, business models, product development and marketing in the sector. This is a valuable source for biotechnologists, bioinformaticians, clinicians and members of biomedical and healthcare fields who need to understand more about the promising developments of the emerging field of biotechnology in healthcare. - Presents the progress and innovations that biotechnology has accomplished in the field of healthcare - Discusses the impact of healthcare biotechnology in global economics and business prospects - Explains how biotechnology revolutionizes future healthcare approaches
Agriculture in the 21st century will need considerable modification to remain both productive and sustainable. Greater production is needed to meet the needs of our still-growing populations and to combat hunger and poverty. Declines in soil health and the pollution of water sources are making many of our production systems less tenable. These adverse trends are exacerbated more and more by the impacts of climate change. There are, fortunately, alternative methods available for agricultural practice that can countervail these constraints. Biological Approaches to Regenerative Soil Systems brings together the work of both researchers and practitioners to map out better approaches to contemporary agriculture that draw upon both old and new knowledge. It presents the science that underlies more biologically driven strategies as well as contemporary innovative experiences in diverse parts of the world. Both accepted research and these varied experiences encourage confidence that these approaches, not relying primarily on the introduction of new varieties and on exogenous inputs, can succeed. This book updates and revises a preceding volume Biological Approaches to Sustainable Soil Systems published by CRC Press in 2006. So much has been learned and done on this subject in the past decade and a half that a second edition was warranted. For instance, the first edition was published, knowledge about plant-soil microbiomes, which are a frequent focus in this book, has mushroomed. Because sustainability is a broad term and an end-state, the editors preferred to assemble expertise regarding regenerative agriculture, which is concerned with the means for achieving sustainability. The concept of regenerative soil systems, entities that are more complex and multifaceted than "soil" alone, also incorporates a concern with having more resilient agricultural systems, ones that are better able to cope with the multiple stresses of climate change that are foreseen for the decades ahead. The book’s chapters representing a wide range of disciplines were contributed by 84 scientists and practitioners from 20 countries. Although they come from persons with in-depth knowledge of their respective fields, the chapters are written to be accessible to readers who are not trained in the specialized subjects. Taken together, the chapters provide students, researchers, practitioners, planners, and policy makers with a comprehensive understanding of both the science and the steps needed to regenerate and sustain soil systems around the world for the long-term benefit of humankind and the environment.
This book will cover several topics to elaborate how proteomics may enhance agricultural productivity. These include crop and food proteomics, farm animal proteomics, aquaculture, microorganisms and insect proteomics. It will also cover several technical advances, which may address the current need for comprehensive proteome analysis.An emerging field of the proteomics aim is to integrate knowledge from basic sciences and to translate it into agricultural applications to solve issues related to economic values of farm animals, crops, food security, health, and energy sustainability. Given the wealth of information generated and to some extent applied in agriculture, there is the need for more efficient and broader channels to freely disseminate the information to the scientific community.