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Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics. Provides in depth knowledge about pathogen biology and microbial adaptations, microbe-host interactions, impact of pathogens on host physiology, virulent factors produced by pathogens and pharmaceutical applications, mechanism of pathogenic virulent factors Covers all tactics and strategies adopted by bacteria for their survival under stressed conditions Focuses on mechanistic insights of pathogenic adaptations to host Includes different adaptation mechanisms of extremophiles to extreme environment
Provides information on how to survive the major threats to human life, cold, heat, thirst, and physical exertion, and provides tips about how to survive in a group
Extremophiles have unique physiological properties, thus considered to be ideal candidates for industrial development. This book present concepts on cold-adapted microorganisms, centered on four different aspects - (i) diversity of cold adapted microbes (ii) their ecology, physiology and metabolism (iii) omics research in the field and (iv) their potential applications. This volume collates the recent developments and innovations with respect to these microorganisms. This book is meant for researchers, biochemists, industries, and government agencies interested in cold active microbes and their products. Also, would be of interest to NGOs and progressive farmers which are working for higher altitude ecosystems throughout the globe.
How do warlords survive and even thrive in contexts that are explicitly set up to undermine them? How do they rise after each fall? Warlord Survival answers these questions. Drawing on hundreds of in-depth interviews in Afghanistan between 2007 and 2018, with ministers, governors, a former vice-president, warlords and their entourages, opposition leaders, diplomats, NGO workers, and local journalists and researchers, Romain Malejacq provides a full investigation of how warlords adapt and explains why weak states like Afghanistan allow it to happen. Malejacq follows the careers of four warlords in Herat, Sheberghan, and Panjshir—Ismail Khan, Abdul Rashid Dostum, Ahmad Shah Massoud, and Mohammad Qasim Fahim). He shows how they have successfully negotiated complicated political environments to survive ever since the beginning of the Soviet-Afghan war. The picture he paints in Warlord Survival is one of astute political entrepreneurs with a proven ability to organize violence. Warlords exert authority through a process in which they combine, instrumentalize, and convert different forms of power to prevent the emergence of a strong, centralized state. But, as Malejacq shows, the personal relationships and networks fundamental to the authority of Ismail Khan, Dostum, Massoud, and Fahim are not necessarily contrary to bureaucratic state authority. In fact, these four warlords, and others like them, offer durable and flexible forms of power in unstable, violent countries.
From Simon & Schuster, Strategy in Action is Boris Yavitz and William H. Newman's guide to the execution, politics, and payoff of business planning. Two management consultants explain how to transform business objectives into strategic action, detailing measures for changing business practices, eliminating ineffective personnel, and instilling confidence through well-defined statements of goals and missions.
The Turnaround Experience is a study of 16 attempted business turnarounds, each studied for twenty years. Nine were successful and seven unsuccessful, the differences owing to the strategies employed, the managerial skills, and character traits on the part of the people involved.The proposition advanced here is that the successful turnarounds focuses involved conscientious, carefully orchestrated efforts aimed at improving the firm's effectiveness as an efficient low-cost producer of increasingly differentiated quality products simultaneously. This study also revealed that successful turnarounds involve leaders who focus on operations, possess strong ethical values, have good personal reputations, and follow the principles of fair play in dealing with employees, creditors, suppliers, and customers.The 16 cases were drawn from actual documented histories occurrences spanning more than 80 years from 1902 to 1988 in the automobile and agricultural equipment industries where much material is available on the events and the characteristics of the people involved.
Organizations are commonly thrust into hostile operating environments where they are required to make strategic decisions that involve significant and costly tradeoffs. Such hostile environments may be endemic such as an economic recession or idiosyncratic such as a predatory action by an adversary. Many features of such hostile environments parallel those of living organisms that also demonstrate fine-tuned strategies to improve their survivability under adverse conditions. How can organizations use these “bioinspired strategies” to survive, and even potentially innovate? This book shows that the same three capabilities essential for the survival of living organisms in harsh environments – efficiency, resilience, and prominence – are also critical for organizations in their process of navigating through their own hostile environments. Throughout the book, the authors provide organizational executives with a systematic framework for thinking about strategic decision-making in a hostile environment leaning on analysis of real-world cases to draw out ontologies and methods for guiding their teams through disruptions, change management, innovation, and process improvements. In the first part, organizations are provided with a systematic approach to analyzing three survivability influences – forces, resources, and observers and their interrelationships. While all three influences are active across all organisms (and organizations), the exact nature of their interrelationship and the significance of each influence are unique to every organism (or organization). The framework helps organizations nail down the specific features of their operating environment that can help or hinder survivability by analyzing the three influences. Organizations can respond to external influences by developing three-pronged capabilities – efficiency, resilience, and prominence (ERP) – that respond to the three survivability influences. Organizations often struggle with identifying the appropriate strategies to apply under different conditions. Fortunately, nature provides several mechanisms that can be analogically applied to guide business strategies. The book contains many illustrations and examples of strategic principles observed among living organisms that can help an organization develop ERP capability. Finally, the book introduces seven strategic design heuristics – Combination, Elimination, Separation, Segmentation, Replication, Dynamics, and Maximization – observed in a living system that can be flexibly utilized to generate ideas to achieve strategic ends.