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How can a smartwatch help patients with diabetes manage their disease? Why can’t patients find out prices for surgeries and other procedures before they happen? How can researchers speed up the decade-long process of drug development? How will "Precision Medicine" impact patient care outside of cancer? What can doctors, hospitals, and health systems do to ensure they are maximizing high-value care? How can healthcare entrepreneurs find success in this data-driven market? A revolution is transforming the $10 trillion healthcare landscape, promising greater transparency, improved efficiency, and new ways of delivering care. This new landscape presents tremendous opportunity for those who are ready to embrace the data-driven reality. Having the right data and knowing how to use it will be the key to success in the healthcare market in the future. We are already starting to see the impacts in drug development, precision medicine, and how patients with rare diseases are diagnosed and treated. Startups are launched every week to fill an unmet need and address the current problems in the healthcare system. Digital devices and artificial intelligence are helping doctors do their jobs faster and with more accuracy. MoneyBall Medicine: Thriving in the New Data-Driven Healthcare Market, which includes interviews with dozens of healthcare leaders, describes the business challenges and opportunities arising for those working in one of the most vibrant sectors of the world’s economy. Doctors, hospital administrators, health information technology directors, and entrepreneurs need to adapt to the changes effecting healthcare today in order to succeed in the new, cost-conscious and value-based environment of the future. The authors map out many of the changes taking place, describe how they are impacting everyone from patients to researchers to insurers, and outline some predictions for the healthcare industry in the years to come.
This volume details a comprehensive set of methods and tools for Hi-C data processing, analysis, and interpretation. Chapters cover applications of Hi-C to address a variety of biological problems, with a specific focus on state-of-the-art computational procedures adopted for the data analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Hi-C Data Analysis: Methods and Protocols aims to help computational and molecular biologists working in the field of chromatin 3D architecture and transcription regulation.
Gratitude, like other positive emotions, has inspired many theological and philosophical writings, but it has inspired very little vigorous, empirical research. In an effort to remedy this oversight, this volume brings together prominent scientists from various disciplines to examine what has become known as the most-neglected emotion. The volume begins with the historical, philosophical, and theoretical foundations of gratitude, then presents the current research perspectives from social, personality, and developmental psychology, as well as from primatology, anthropology, and biology. The volume also includes a comprehensive, annotated bibliography of research on gratitude. This work contributes a great deal to the growing positive psychology initiative and to the scientific investigation of positive human emotions. It will be an invaluable resource for researchers and students in social, personality, and developmental, clinical, and health psychology, as well as to sociologists and cultural anthropologists.
Who's better? Billie Holiday or P. J. Harvey? Blur or Oasis? Dylan or Keats? And how many friendships have ridden on the answer? Such questions aren't merely the stuff of fanzines and idle talk; they inform our most passionate arguments, distill our most deeply held values, make meaning of our ever-changing culture. In Performing Rites, one of the most influential writers on popular music asks what we talk about when we talk about music. What's good, what's bad? What's high, what's low? Why do such distinctions matter? Instead of dismissing emotional response and personal taste as inaccessible to the academic critic, Simon Frith takes these forms of engagement as his subject--and discloses their place at the very center of the aesthetics that structure our culture and color our lives. Taking up hundreds of songs and writers, Frith insists on acts of evaluation of popular music as music. Ranging through and beyond the twentieth century, Performing Rites puts the Pet Shop Boys and Puccini, rhythm and lyric, voice and technology, into a dialogue about the undeniable impact of popular aesthetics on our lives. How we nod our heads or tap our feet, grin or grimace or flip the dial; how we determine what's sublime and what's "for real"--these are part of the way we construct our social identities, and an essential response to the performance of all music. Frith argues that listening itself is a performance, both social gesture and bodily response. From how they are made to how they are received, popular songs appear here as not only meriting aesthetic judgments but also demanding them, and shaping our understanding of what all music means.
The artificial intelligence (AI) landscape has evolved significantly from 1950 when Alan Turing first posed the question of whether machines can think. Today, AI is transforming societies and economies. It promises to generate productivity gains, improve well-being and help address global challenges, such as climate change, resource scarcity and health crises.
An unparalleled exploration of the mysteries underlying women's sexuality that rivals the culture-shifting Kinsey Report, from two of America's leading research psychologists Do women have sex simply to reproduce or display their affection? When University of Texas at Austin clinical psychologist Cindy M. Meston and evolutionary psychologist David M. Buss joined forces to investigate the underlying sexual motivations of women, what they found astonished them. Through the voices of real women, Meston and Buss reveal the motivations that guide women's sexual decisions and explain the deep-seated psychology and biology that often unwittingly drive women's desires—sometimes in pursuit of health or pleasure, or sometimes for darker, disturbing reasons that a woman may not fully recognize. Drawing on more than a thousand intensive interviews conducted solely for the book, as well as their pioneering research on physiological response and evolutionary emotions, Why Women Have Sex uncovers an amazingly complex and nuanced portrait of female sexuality. They delve into the use of sex as a defensive tactic against a mate's infidelity (protection), as a ploy to boost self-confidence (status), as a barter for gifts or household chores (resource acquisition), or as a cure for a migraine headache (medication). Why Women Have Sex stands as the richest and deepest psychological understanding of female sexuality yet achieved and promises to inform every woman's (and her partner's) awareness of her relationship to sex and her sexuality.
This very intresting compilation, written by the son of he first photographer and journalist of Ceylon, is of the various important dates in the history starting with the advent of the Portuguese in 1505. Its goes on to cover the Dutch period in a short cap to reach the copious section of the British period that commenced in 1795 and continues till the authors time of compiling in the 1920 s. Although the eras of the Portuguese and Dutch are over in a few pages. The record of the events of the British stretch over 125 pages. Another wonderful part of this book is 442 short notes on the places, people, history, scandals, poetry, celebrations, arrival of ships that make the book interesting to those who know Jaffna only by name.
Editor Joseph P. Byrne, together with an advisory board of specialists and over 100 scholars, research scientists, and medical practitioners from 13 countries, has produced a uniquely interdisciplinary treatment of the ways in which diseases pestilence, and plagues have affected human life. From the Athenian flu pandemic to the Black Death to AIDS, this extensive two-volume set offers a sociocultural, historical, and medical look at infectious diseases and their place in human history from Neolithic times to the present. Nearly 300 entries cover individual diseases (such as HIV/AIDS, malaria, Ebola, and SARS); major epidemics (such as the Black Death, 16th-century syphilis, cholera in the nineteenth century, and the Spanish Flu of 1918-19); environmental factors (such as ecology, travel, poverty, wealth, slavery, and war); and historical and cultural effects of disease (such as the relationship of Romanticism to Tuberculosis, the closing of London theaters during plague epidemics, and the effect of venereal disease on social reform). Primary source sidebars, over 70 illustrations, a glossary, and an extensive print and nonprint bibliography round out the work.