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This thesis presents various applications of graphene-based nanomaterials, especially in biomedicine. Graphene and its derivatives have gained enormous attention from scientists in all fields of study due to many unprecedented properties. The initial scientific attention was focused on the development of transparent flexible electrodes by exploiting two-dimensional graphene film’s extraordinary electrical and physical properties. Recently, given an increasing evidence of dispersed graphene-based nanomaterials’ biocompatibility, researchers have endeavored to employ these materials in other studies relevant to biomedical technologies. In this respect, the thesis provides a comprehensive review on the synthesis, toxicity, and a few of the key biomedical applications in the first chapter. The following chapter discusses the use of a graphene film as a novel catalyst to oxidatively destroy phenols, which are known to be potentially mutagenic and carcinogenic. Finally, and most importantly, the last chapter introduces the therapeutic role of graphene quantum dots, the smallest graphene-based nanomaterials, for Parkinson’s disease. The results are promising for the use of graphene quantum dots as the basis of future clinical drug candidates for neurodegenerative disorders. ​
Biomedical Applications of Graphene and 2D Nanomaterials provides a much-needed reference on the biomedical applications of 2D nanomaterials, as well as theoretical knowledge on their structure, physicochemical properties and biomedical applications. Chapters are dedicated to growth areas, such as size and shape-dependent chemical and physical properties and applications, such as in diagnostic and therapeutic products. The book also discusses the concept, development and preclinical studies of 2D nanomaterials-based biomedical tools, such as biosensors, artificial organs and photomedicine. Case studies and reports form the core of the book, making it an ideal resource on potential applications in biomedical science and engineering. This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications. - Presents advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials - Provides state-of-the-art biomedical applications for 2D nanomaterials, including graphene and boron nitride - Includes key information from a broad selection of subject areas for researchers in both materials, engineering and medicine
This thesis presents various applications of graphene-based nanomaterials, especially in biomedicine. Graphene and its derivatives have gained enormous attention from scientists in all fields of study due to many unprecedented properties. The initial scientific attention was focused on the development of transparent flexible electrodes by exploiting two-dimensional graphene film’s extraordinary electrical and physical properties. Recently, given an increasing evidence of dispersed graphene-based nanomaterials’ biocompatibility, researchers have endeavored to employ these materials in other studies relevant to biomedical technologies. In this respect, the thesis provides a comprehensive review on the synthesis, toxicity, and a few of the key biomedical applications in the first chapter. The following chapter discusses the use of a graphene film as a novel catalyst to oxidatively destroy phenols, which are known to be potentially mutagenic and carcinogenic. Finally, and most importantly, the last chapter introduces the therapeutic role of graphene quantum dots, the smallest graphene-based nanomaterials, for Parkinson’s disease. The results are promising for the use of graphene quantum dots as the basis of future clinical drug candidates for neurodegenerative disorders. ​
Learn to Use Nanoscale Materials to Design Novel Biomedical Devices and Applications Discover how to take full advantage of nanoscale materials in the design and fabrication of leading-edge biomedical devices. The authors introduce you to a variety of possible clinical applications such as drug delivery, diagnostics, and cancer therapy. In addition, the authors explore the interface between micron and nanoscale materials for the development of applications such as tissue engineering. Finally, they examine the mechanisms of cell interactions with material surfaces through the use of nanotechnology-based material processing and characterization methods. The text's three sections highlight its interdisciplinary approach: * Part One: Nanostructure Fabrication * Part Two: Bio-Nano Interfaces * Part Three: Clinical Applications of Nanostructures Among the key topics covered are nanotechnology in tissue regeneration; biomolecular engineering; receptor-ligand interactions; cell-biomaterial interactions; nanomaterials in diagnostics, drug delivery, and cancer therapy; and nano- and micron-level engineering and fabrication. Throughout the text, clear examples guide you through the chemistry and the processing involved in designing and developing nanoscale materials for biomedical devices. Each chapter begins with an introduction and ends with a conclusion highlighting the key points. In addition, references at the end of the chapter help you expand your research on any individual topic. In summary, this book helps biomedical researchers and engineers understand the physical phenomena that occur at the nanoscale in order to design novel cell-based constructs for a wide range of applications.
This book highlights the evolution of, and novel challenges currently facing, nanomaterials science, nanoengineering, and nanotechnology, and their applications and development in the biological and biomedical fields. It details different nanoscale and nanostructured materials syntheses, processing, characterization, and applications, and considers improvements that can be made in nanostructured materials with their different biomedical applications. The book also briefly covers the state of the art of different nanomaterials design, synthesis, fabrication and their potential biomedical applications. It will be particularly useful for reading and research purposes, especially for science and engineering students, academics, and industrial researchers.
Graphene Bioelectronics covers the expending field of graphene biomaterials, a wide span of biotechnological breakthroughs, opportunities, possibilities and challenges. It is the first book that focuses entirely on graphene bioelectronics, covering the miniaturization of bioelectrode materials, bioelectrode interfaces, high-throughput biosensing platforms, and systemic approaches for the development of electrochemical biosensors and bioelectronics for biomedical and energy applications. The book also showcases key applications, including advanced security, forensics and environmental monitoring. Thus, the evolution of these scientific areas demands innovations in crosscutting disciplines, starting from fabrication to application. This book is an important reference resource for researchers and technologists in graphene bioelectronics—particularly those working in the area of harvest energy biotechnology—employing state-of-the-art bioelectrode materials techniques. - Offers a comprehensive overview of state-of-art research on graphene bioelectronics and their potential applications - Provides innovative fabrication strategies and utilization methodologies, which are frequently adopted in the graphene bioelectronics community - Shows how graphene can be used to make more effective energy harvesting devices
Carbon nanomaterials have a unique place in Nanoscience owing to their exceptional electrical, thermal, chemical and mechanical properties and have found application in areas as diverse as composite materials, energy storage and conversion, sensors, drug delivery, field emission devices and nano-scale electronic components. Conjugated carbon nanomaterial covers the areas of carbon nanotubes, fullerenes and graphene. Graphene is the newest of the carbon nanomaterials and promises to be a very active field. Already since its isolation in 2004 it has grabbed the attention of the chemistry, materials and physics communities. It promises to rival carbon nanotubes in terms of properties and potential applications with the number of publications rising from ca. 130 in 2005 to ca. 2,800 in 2010. In this short book Sekhar Ray gives an overview on graphene and graphene-oxide with a strong focus on applications. Structured in three chapters, one on graphene, one on graphene-oxide and one on graphene based nanoparticles his resource describes in each chapter the preparation (including synthesis and functionalization) and material properties before detailing a whole range of applications. Ray finishes each chapter with information on remaining challenges and perspectives. - Written by an expert in the field who, during his last 17 years of research, has published more than 80 peer reviewed articles in recognized international journals - Gives full-chapter overviews on Graphene, Graphene-Oxide, and Graphene based nanoparticles - Focusses on applications
Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. - Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view - Presents the recent progress related to nanotherapeutics in the oral cavity - Provides the recent progress in the field of biomedical nanoparticles
Nature, by dint of its constitution, harbors many unassuming mysteries broadly manifested by its constituent cohorts. If physics is the pivot that holds nature and chemistry provides reasons for its existence, then the rest is just manifestation. Nanoscience and technology harbor the congruence of these two core subjects, whereby many phenomenon may be studied in the same perspective. That nature operates at nanoscale—obeying the principles of thermodynamics and supramolecular chemistry—is a well understood fact manifested in a variety of life processes: bones are restored after a fracture; clots potentially leading to cerebral strokes can be dissolved. The regeneration of new structures in our system follows a bottom-up approach. Be it a microbe (benign or pathogenic), plant (lower or higher), plant parts/organs, food beneficiaries, animal (lower), higher animal processing wastes, these all are found to deliver nanomaterials under amenable processing conditions. Identically, the molecules also seem to obey the thermodynamic principles once they get dissociated/ionized and the energy captured in the form of bonding helps in the synthesis of a myriad of nanomaterials. This edited volume explores the various green sources of nanomaterial synthesis and evaluates their industrial and biomedical applications with a scope of scaling up. It provides useful information to researchers involved in the green synthesis of nanomaterials in fields ranging from medicine to integrated agricultural management.
Nanomaterials can be synthesized by physical, chemical, and biological methods; however, the latter technique is preferred as it is eco-friendly, non-toxic, and cost-effective. The green synthesized nanomaterials have been found to be more efficient with potential applications in diverse fields. It is crucial to explore green synthesized nanomaterials and the applications that can be made in order to support water remediation, pharmaceuticals, food processing, construction, and more. The Handbook of Research on Green Synthesis and Applications of Nanomaterials provides a multidisciplinary approach to the awareness of using non-toxic, eco-friendly, and economical green techniques for the synthesis of various nanomaterials, as well as their applications across a variety of fields. Covering topics such as antimicrobial applications, environmental remediation, and green synthesis, this book acts as a thorough reference for engineers, nanotechnology professionals, academicians, students, scientists, and researchers pursuing research in the nanotechnology field.