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Multiscale Biomechanics provides new insights on multiscale static and dynamic behavior of both soft and hard biological tissues, including bone, the intervertebral disk, biological membranes and tendons. The physiological aspects of bones and biological membranes are introduced, along with micromechanical models used to compute mechanical response. A modern account of continuum mechanics of growth and remodeling, generalized continuum models to capture internal lengths scales, and dedicated homogenization methods are provided to help the reader with the necessary theoretical foundations. Topics discussed include multiscale methods for fibrous media based on discrete homogenization, generalized continua constitutive models for bone, and a presentation of recent theoretical and numerical advances. In addition, a refresher on continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods is given in separate chapters. Numerical aspects are treated in detail, and simulations are presented to illustrate models. This book is intended for graduate students and researchers in biomechanics interested in the latest research developments, as well as those who wish to gain insight into the field of biomechanics. - Provides a clear exposition of multiscale methods for fibrous media based on discrete homogenization and the consideration of generalized continua constitutive models for bone - Presents recent theoretical and numerical advances for bone remodeling and growth - Includes the necessary theoretical background that is exposed in a clear and self-contained manner - Covers continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods
This book provides readers with an elementary understanding of the material behavior of structural silicones in façades. Based on extensive experimental investigations on a transparent structural silicone adhesive (TSSA), the material behavior, failure, and microscopic effects such as stress whitening, cavitation failure, and the Mullins effect are analyzed. In turn, novel hyperelastic material models are developed to account for nonlinear material behavior under arbitrary deformations. The development of a volumetric hyperelastic model makes it possible for the first time to approximate the structural behavior of TSSA under constrained tensile load and cavitation. The material models discussed here were implemented in a finite element code for validation, and their quality was confirmed by three-dimensional numerical simulations, in which an additional stretch-based failure criterion was evaluated for failure prediction. The numerical studies are in good agreement with the experimental results.
This book presents the various approaches in establishment the basic equations of one- and two-dimensional structural elements. In addition, the boundaries of validity of the theories and the estimation of errors in approximate theories are given. Many contributions contain not only new theories, but also new applications, which makes the book interesting for researcher and graduate students.
Ever since King Solomon built the Holy Temple on Jerusalem's Temple Mount, Jews around the world have seen the holy city as the core of their lives. Jews from every continent on the globe have always prayed three times a day facing Jerusalem. Jews from Yemen, Ethiopia, and Lithuania; Jews from Morocco, Spain, India, Poland, and Russia.

The Belmont Report

United States. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research

Published: 1978

Total Pages: 614


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Human rights offer a vision of international justice that today’s idealistic millions hold dear. Yet the very concept on which the movement is based became familiar only a few decades ago when it profoundly reshaped our hopes for an improved humanity. In this pioneering book, Samuel Moyn elevates that extraordinary transformation to center stage and asks what it reveals about the ideal’s troubled present and uncertain future. For some, human rights stretch back to the dawn of Western civilization, the age of the American and French Revolutions, or the post–World War II moment when the Universal Declaration of Human Rights was framed. Revisiting these episodes in a dramatic tour of humanity’s moral history, The Last Utopia shows that it was in the decade after 1968 that human rights began to make sense to broad communities of people as the proper cause of justice. Across eastern and western Europe, as well as throughout the United States and Latin America, human rights crystallized in a few short years as social activism and political rhetoric moved it from the hallways of the United Nations to the global forefront. It was on the ruins of earlier political utopias, Moyn argues, that human rights achieved contemporary prominence. The morality of individual rights substituted for the soiled political dreams of revolutionary communism and nationalism as international law became an alternative to popular struggle and bloody violence. But as the ideal of human rights enters into rival political agendas, it requires more vigilance and scrutiny than when it became the watchword of our hopes.
This book is devoted to the mathematical optimization theory and modeling techniques that recently have been applied to the problem of controlling the shape and intensity of the power density distribution in the core of large nuclear reactors. The book has been prepared with the following purposes in mind: 1. To provide, in a condensed manner, the background preparation on reactor kinetics required for a comprehensive description of the main problems encountered in designing spatial control systems for nuclear reactor cores. 2. To present the work that has already been done on this subject and provide the basic mathematical tools required for a full understand ing of the different methods proposed in the literature. 3. To stimulate further work in this challenging area by weighting the advantages and disadvantages of the existing techniques and evaluating their effectiveness and applicability. In addition to coverage of the standard topics on the subject of optimal control for distributed parametersystems, the book includes, at amathemati cal level suitable for graduate students in engineering, discussions of con ceptsoffunctional analysis, the representation theory ofgroups, and integral equations. Although these topics constitute a requisite for a full understanding of the new developments in the area of reactor modeling and control, they are seidom treated together in a single book and, when they are, their presenta tion isoften directed to the mathematician.They are thus relatively unknown to the engineering community.
The result of two years work by 19 experienced policymakers and two Nobel prize-winning economists, 'The Growth Report' is the most complete analysis to date of the ingredients which, if used in the right country-specific recipe, can deliver growth and help lift populations out of poverty.
Biography of pathologist Dr. Jack Kevorkian, discussing his life and his involvement with assisted suicide.