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"To 'Bot or Not To 'Bot": Sonic journeys with Uncle Chuck and Muttski to foil Robotnik's latest scheme: an unstoppable army of his new "Combots!" Everything is going according to plan...until Uncle Chuck and Muttski turn traitor!
Fan-favorite artist Evan Stanley takes over as writer! A new storyline begins, perfect for new readers, as Sonic races to help a friend in need! Hold on to your chili dogs, Sonic fans! The Metal Virus is gone, but things aren't back to normal. Omega is damaged, and his allies turn to Sonic for help. The only way to rebuild him is to trade parts with a mysterious champion Chao racer, so it's off to the races for Cream, Cheese, Amy, and Rouge! They'll have to keep up their winning streak or surrender Cheese to Clutch's evil... clutches! Meanwhile, Sonic and Tails are being watched by a mysterious figure in Dr. Eggman's seemingly abandoned base, but when Rouge's team calls for help, will this shadowy character prove friend or foe? Please keep your arms and legs inside the ride at all times, folks, this is going to be a bumpy one! Collects IDW's Sonic the Hedgehog issues #33–36.
After 30 years of going fast, it’s time for fans to celebrate the speediest hedgehog of all time! It’s an unbelievable birthday celebration for Sonic the Hedgehog with his first Classic Sonic special! First, in “Seasons of Chaos” by longtime Sonic scribe Ian Flynn and artists Aaron Hammerstrom & Reggie Graham, Sonic goes on an adventure from pleasant spring valleys to wintry wonderlands in search of the Chaos Emeralds. But Sonic’s not alone, with a little help from his friends Miles “Tails” Prower, Knuckles the Echidna, Amy Rose, Mighty the Armadillo, and Ray the Flying Squirrel, they’ll race, fight, and fly their way to victory against the baddest of baddies! Then, in “Dr. Eggman’s Birthday,” the vile, villainous Dr. Eggman takes center stage in a story written by New York Times bestseller Gale Galligan (The Babysitters Club)! And how does the bad doctor celebrate the occasion? Only his Badniks know for sure... Finally, in "Sonic Learns to Drive," Sonic's up against a tough challenge: Driving! When the fastest thing alive can outrun any car, will Sonic have the patience to learn... or will he finally get left in the dust? Written by the hosts of My Brother, My Brother, and Me, The Adventure Zone, and New York Times bestsellers, the McElroy Brothers! Grab a slice of chili dog cake and don’t get left in the dust on the most way past cool book of the year!
Oversized hardcover editions of IDW's celebrated Sonic The Hedgehog comic books, including the ongoing series, annuals, and mini-series, all presented in recommended reading order. Everything a beginner could need, everything a diehard could want! ON YOUR MARKS. GET SET. GO! The adventure begins here as Sonic races to protect the world from bad guys old and new! In the aftermath of his latest battle with Dr. Eggman, rogue robots are on the loose and new foes are on the rise. But where is the evil doctor and what secrets will Sonic discover during his search? One thing's for sure: he'll need plenty of help from Tails, Knuckles, Amy, and new allies Tangle the Lemur and Whisper the Wolf. Plus, he'll have to deal with a little competition--from his old frenemy Shadow the Hedgehog! It's an epic storyline Sonic fans can't miss, so don't get left in the dust. Gotta go fast! Collects the first 12 issues from volumes 1-3 (Fallout, The Fate of Dr. Eggman, and Battle For Angel Island) of the Sonic The Hedgehog series.
"Babylon Rising," Part Two. The Babylon Rogues have found the way to revive the long-lost city of Babylon Garden! The only thing standing in their way is the entire Battle Bird Armada. Feathers fly as the feuding factions finally throw down for the first time! Rogues vs. Armada! Jet vs. Speedy! The Battle Lord in action! You cannot miss this intense installment!
Archie Marries Veronica—“Up in the Air!”: Archie and Veronica are doing their best to not let the tumultuous events of their lives effect the love they have for one another. And they’re doing pretty well, too, but is love enough to keep their legal battles at bay? Speaking of love and battles, Jughead and Ethel have some planning to do… but hopefully their stubbornness won’t get in the way! And Kevin’s trying his best to not let people’s perceptions of him effect his Senate job, perhaps some encouraging words is all he needs. And Clay’s back to work—but things still seem new and strange. Could it just be his imagination? Archie Marries Betty—“Not So Great Expectations!”: Archie’s finally had enough of Betty’s busy schedule—and he’s not the only one! Will all of her hard work have paid off or has it only made matters worse? And who is it Archie’s really mad at—Betty for neglecting him? Or himself for being selfish and feeling guilty? Meanwhile, Kevin dives head first into the investigation on the nearby mall shooting after discovering that the tragedy hit closer to home than he ever could have imagined. And Jughead’s waiting on bated breath as Midge’s due date draws closer and closer. Oh baby, things are crazy in Riverdale!
Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.
The book discusses recent findings and current perspectives on therapeutic angiogenesis. Studies have shown that therapies such as cell implantation and transfer of gene encoding for angiogenic growth factors are effective in improving symptoms in patients with critical limb ischemia, who previously had no treatment option other than amputation. The book discusses these therapies and presents data collected in clinical studies over the past decade. Despite significant advances in therapeutic angiogenesis since the first clinical studies in the early 21st century, it has been largely ignored in the literature. This comprehensive book fills that gap, making it a valuable resource for both researchers and practitioners alike.
In this issue, guest editors bring their considerable expertise to this important topic. - Contains 13 relevant, practice-oriented topics including PSC, small duct PSC, IgG4 and ischemic cholangiopathy: what do you see on needle biopsy?; evolving understanding of noncirrhotic portal hypertension; practical guide, challenges, and pitfalls in liver fibrosis staging; liver pathology after hematopoietic stem cell transplant; medical Liver injury related to cancer treatment; and more. - Provides in-depth clinical reviews on liver pathology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic possibilities. The book covers a wide range of conditions, from food allergies, constipation, chronic liver disease and IBS, also exploring emerging techniques to diagnose and normalize functions of the GI tract. As a highly referenced book, this is a useful resource for gastroenterologists, physiologists, internists, professional researchers and instructors teaching courses for clinical and research students. - Discusses the multiple processes governing gastrointestinal function - Presents new information on the brain-gut axis and microbiome - Edited by preeminent scientists in the field - Includes coverage of issues, such as food allergies, constipation, chronic liver disease, IBS, Crohn's disease, and more