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A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.
MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.
Colliding with and confronting The Tempest and postcolonial identity, the poems in Safiya Sinclair's Cannibal explore Jamaican childhood and history, race relations in America, womanhood, otherness, and exile. She evokes a home no longer accessible and a body at times uninhabitable, often mirrored by a hybrid Eve/Caliban figure. Blooming with intense lyricism and fertile imagery, these full-blooded poems are elegant, mythic, and intricately woven. Here the female body is a dark landscape; the female body is cannibal. Sinclair shocks and delights her readers with her willingness to disorient and provoke, creating a multitextured collage of beautiful and explosive poems.
From the author of the New York Times bestseller The Plant Paradox comes a groundbreaking plan for living a long, healthy, happy life. From the moment we are born, our cells begin to age. But aging does not have to mean decline. World-renowned surgeon Dr. Steven Gundry has been treating mature patients for most of his career. He knows that everyone thinks they want to live forever, until they hit middle age and witness the suffering of their parents and even their peers. So how do we solve the paradox of wanting to live to a ripe old age—but enjoy the benefits of youth? This groundbreaking book holds the answer. Working with thousands of patients, Dr. Gundry has discovered that the “diseases of aging” we most fear are not simply a function of age; rather, they are a byproduct of the way we have lived over the decades. In The Longevity Paradox, he maps out a new approach to aging well—one that is based on supporting the health of the “oldest” parts of us: the microorganisms that live within our bodies. Our gut bugs—the bacteria that make up the microbiome—largely determine our health over the years. From diseases like cancer and Alzheimer’s to common ailments like arthritis to our weight and the appearance of our skin, these bugs are in the driver’s seat, controlling our quality of life as we age. The good news is, it’s never too late to support these microbes and give them what they need to help them—and you—thrive. In The Longevity Paradox, Dr. Gundry outlines a nutrition and lifestyle plan to support gut health and live well for decades to come. A progressive take on the new science of aging, The Longevity Paradox offers an action plan to prevent and reverse disease as well as simple hacks to help anyone look and feel younger and more vital.
A compelling graphic novel adaptation of Upton Sinclair's seminal protest novel that brings to life the harsh conditions and exploited existences of immigrants in Chicago's meatpacking industry in the early twentieth century. Long acclaimed around the world, Upton Sinclair's 1906 muckraking novel The Jungle remains a powerful book even today. Not many works of literature can boast that their publication brought about actual social and labor change, but that's just what The Jungle did, as it led to the passage of the Pure Food and Drug Act of 1906. In today's society, where labor and safety of the food we eat remain key concerns for all, Sinclair's shocking story still resonates. Bringing new life and energy to this classic work, adapter and illustrator Kristina Gehrmann takes Sinclair's prose and transforms it through pen and ink, allowing you to discover (or rediscover) this book and see it from a whole new perspective.
Carol Milford dreams of living in a small, rural town. But Gopher Prairie, Minnesota, isn't the paradise she'd imagined. First published in 1920, this unabridged edition of the Sinclair Lewis novel is an American classic, considered by many to be his most noteworthy and lasting work. As a work of social satire, this complex and compelling look at small-town America in the early 20th century has earned its place among the classics.
Questions! Questions! Questions! Children are full of them. Where did I come from? What is God like? Is there only one God? The Big Book of Questions and Answers is a family guide to the Christian Faith. It contains a wealth of activities, prayers, and Bible references. These interactive resources will bring families closer together as they learn about the Christian faith.
Hidden in the wild forests of the Appalachian Mountains is a school of magic...and mystery. Ezra Bishop's life crumbles apart after a devastating loss, sending her and her twin sister across the country to a prestigious boarding school for bloodline witches. Atwood Preparatory Academy seems like an ideal place for the sisters to attempt to restart their lives, but it isn't long before peace at the school is broken when one of the students goes missing. One of many... When someone close to her is threatened, Ezra is forced to face a mystery that has haunted the school for centuries. Unraveling the truth of the disappearances goes deeper than Ezra is prepared for, until she finds herself digging the grave of a terrorizing secret. Forging a tense alliance with the Headmaster's sons, Ezra may be better off on her own as she discovers the boys are harboring dangerous secrets of their own. But the enemy is already here, and as children continue to go missing, Ezra realizes that she has to lay everything on the line to protect those she cares about...even her life.
Botanist Ari lives an isolated life on a space station, tending a lush garden in her quarters. When a woman is given to her as a slave, Ari's ordered life shatters. Her slave is smart, sexy, and seems to know an awful lot about tactics, star charts, and the pirate queen, Mir. A lesbian romance about daring to risk your heart.