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This issue of Critical Care Clinics will focus on Severe Acute Respiratory DIstress Syndrome and dealing with it in the ICU. Topics will include: Challenges and Successes in ARDS Research;Mechanical ventilation with Lung Protective Strategies: What works?; Gene therapy for ALI/ARDS;High Frequency Oscillatory Ventilation in ALI/ARDS;Prone positioning therapy in ARDS;Recovery and Long-term outcome in ARDS; and Experimental models and emergeing hypotheses for ALI and ARDS
This issue of Critical Care Clinics, guest edited by Drs. Michael Matthay and Kathleen Dori Lui, focuses on Acute Respiratory Distress Syndrome. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: Epidemiology, Environmental Factors, Clinical Diagnosis, Physiology of ARDS, including COVID-19, Pathogenesis Based on Clinical Studies, Genetics of ARDS, Ventilator Management and Rescue Therapy with ECMO, Acute Kidney Injury and ARDS, Pharmacologic Therapies and ARDS and Long Term Outcomes from ARDS. - Provides in-depth, clinical reviews on ARDS, providing actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.
In this issue of Critical Care Clinics, guest editors Drs. Michelle Ng Gong and Gregory S. Martin bring their considerable expertise to the topic of COVID-19. Top experts in the field cover key topics such as ECMO in COVID-19, neurologic manifestations and sequelae in COVID-19, pediatric COVID-19, anti-viral and anti-inflammatory therapeutics in COVID-19, the critical care surge during COVID-19 and lessons for the future, and more. - Contains 11 relevant, practice-oriented topics including post-acute sequelae of SARS CoV-2 infection; COVID-19 and renal failure; the role of acute thrombosis in COVID-19; COVID ARDS: different phenotype of ARDS or same diversity of phenotype in ARDS; COVID-19 in the critically ill pregnant patient; and more. - Provides in-depth clinical reviews on COVID-19, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
This issue of Critical Care Clinics focuses on Mechanical Circulatory Support. Editors Nitin Puri and Michael Baram have assembled an expert team of authors on topics such as: History of ECMO; Evolution current technique and equipment; Program Development; Review ELSO standards; Cardiac Failure of medical management; Cardiac Management and Complications; Pre-Respiratory; Respiratory Management and Complications; Post ECMO management; Post ECMO complication; DVT; Transport- Interhospital and How to prep patient; ECHO; Family understanding of ECMO (to cannulate or not); Pharmacy, Nutrition, Blood Management; Transport; The future of ECMO and ventilation.
This issue of Critical Care Clinics, guest edited by Dr. Mitchell M. Levy, focuses on Biomarkers in Critical Care. This is one of four issues each year selected by the series consulting editor, Dr. John Kellum. Articles in this issue include, but are not limited to: The History of Biomarkers; Biomarkers for Identifying Infection; Procalcitonin: Where Are We Now?; Soluble TREM-1: Diagnosis or Prognosis?; Lubricin as a Biomarker in Sepsis; Check Point Inhibitors and Their Role in Immunosuppression in Sepsis; Metabolomics and the Microbiome as Biomarkers in Sepsis; Lactate: Where Are We Now?; Predicting Renal Dysfunction; Biomarkers in the Evolution of ARDS; Biomarkers and RV Dysfunction; Biomarkers and Precision Medicine: State of the Art; The Use of Biomarkers for Population Homogeneity in Clinical Trials; and The Future of Biomarkers.
This major reference work is the most comprehensive resource on oncologic critical care. The text reviews all significant aspects of oncologic ICU practices, with a particular focus on challenges encountered in the diagnosis and management of the critically ill cancer patient population. Comprised of over 140 chapters, the text explores such topics as the organization and management of an oncologic ICU, diseases and complications encountered in the oncologic ICU, multidisciplinary care, surgical care, transfusion medicine, special patient populations, critical care procedures, ethics, pain management, and palliative care. Written by worldwide experts in the field, Oncologic Critical Care is a valuable resource for intensivists, advance practice providers, nurses, and other healthcare providers, that will help close significant knowledge and educational gaps within the realm of medical care for critically ill cancer patients.
Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.
Guest editor Lena Napolitano has assembled and expert team of authors on the topic of Surgery in the ICU. Articles will focus on: Oxygen Support and Mechanical Ventilation Advances; Ventilator-associated Pneumonia – New Definitions;Optimal Strategies for Severe ARDS; Persistent Inflammation/Immunosuppression Syndrome; ABCDE Bundle in Critical Care;Renal Replacement Therapy in Acute Kidney Injury: Consensus?; Transfusion Advances in Critical Care; Severe Sepsis and Septic Shock: ProCESS; ARISE: PROMISE – What is Optimal Resuscitation?; Nutritional Support in Critical Care: What is the Evidence?; Acute Kidney Injury and Outcomes; and Tracheostomy Update: When and How?