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This Special Issue compiles 11 scientific works that were presented during the International Symposium on Thermal Effects in Gas Flow in Microscale, ISTEGIM 2019, held in Ettlingen, Germany, in October 2019. This symposium was organized in the framework of the MIGRATE Network, an H2020 Marie Skłodowska-Curie European Training Network that ran from November 2015 to October 2019 (www.migrate2015.eu). MIGRATE intends to address some of the current challenges in innovation that face the European industry with regard to heat and mass transfer in gas-based microscale processes. The papers collected in this book focus on fundamental issues that are encountered in microfluidic systems involving gases, such as the analysis of gas–surface interactions under rarefied conditions, the development of innovative integrated microsensors for airborne pollutants, new experimental techniques for the measurement of local quantities in miniaturized devices and heat transfer issues inside microchannels. The variety of topics addressed in this book emphasizes that multi-disciplinarity is the real common thread of the current applied research in microfluidics. We hope that this book will help to stimulate early-stage researchers who are working in microfluidics all around the world. This book is dedicated to them!
Personalised medicine is the next step in healthcare, especially when applied to genetically diverse diseases such as cancers. Naturally, a host of methods need to evolve alongside this, in order to allow the practice and implementation of individual treatment regimens. One of the major tasks for the development of personalised treatment of cancer is the identification and validation of a comprehensive, robust, and reliable panel of biomarkers that guide the clinicians to provide the best treatment to patients. This is indeed important with regards to radiotherapy; not only do biomarkers allow for the assessment of treatability, tumour response, and the radiosensitivity of healthy tissue of the treated patient. Furthermore, biomarkers should allow for the evaluation of the risks of developing adverse late effects as a result of radiotherapy such as second cancers and non-cancer effects, for example cardiovascular injury and cataract formation. Knowledge of all of these factors would allow for the development of a tailored radiation therapy regime. This Special Issue of the Journal of Personalised Medicine covers the topic of Radiation Response Biomarkers in the context of individualised cancer treatments, and offers an insight into some of the further evolution of radiation response biomarkers, their usefulness in guiding clinicians, and their application in radiation therapy.
In recent years, as suggested by Dr. György Buzsáki, such ideas as "Without the rhythm of the brain, the mind is not born" and "The brain is a device that predicts, and it is the rhythm of the brain that produces predictive ability" have come to be accepted. In this context, we have organized a Special Issue presenting the cutting-edge research in clinical neurophysiology, neuroimaging, and neuromodulation.