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Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
Engineering of Nanobiomaterials presents the most recent information regarding the specific modifications of nanomaterials and of their synthesis methods, in order to obtain particular structures for different biomedical purposes. This book enables the results of current research to reach those who wish to use this knowledge in an applied setting. Engineered nanobiomaterials, designed from organic or inorganic raw materials, offer promising alternatives in many biomedical applications. In this book, eminent researchers from around the world discuss the various applications, including antibacterial therapy, biosensors, cancer therapy, stimuli-responsive drug release, drug delivery, gene therapy and visual prostheses. In each case, advantages, drawbacks and future potential are outlined. This book will be of interest to students, postdoctoral researchers and professors engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. - An up-to-date and highly structured reference source for students, researchers and practitioners working in biomedical, biotechnological and engineering fields - A valuable guide to recent scientific progress, covering major and emerging applications of nanomaterials in the biomedical field - Proposes novel opportunities and ideas for developing or improving engineering technologies in nanomedicine/nanobiology
The book examines Turkey’s new foreign policy operating in the new international system. Especially with the AKP government, Turkish foreign policy principles have been changed and/or modified radically. Therefore, new foreign policy mentality has to be analyzed in detail. The book also focuses on the “strategic depth” paradigm of Prof. Dr. Ahmet Davutoglu. In his book, Davutoglu inspects the Turkey’s place within the world politics and its relations neighboring countries through historical-religious lense. In order to understand this new mentality in the Turkish foreign policy, historical developments of the Ottoman Empire and the Turkish Republic has been covered. The book mainly focuses on following subjects: analysis of Turkish foreign policy framework, changes in Turkish government’s foreign policy paradigm, reflections of new approaches in the Turkish foreign policy, Turkey’s shifting foreign policy and the new Turkish foreign policy’s future, continuity and change in Turkish foreign policy and lastly implications of Turkey’s new foreign policy doctrine. Türk dış politikası uzun yıllar gündem yaratma yerine, başka aktörlerin oluşturduğu gündemleri takip etme ve müttefiklik adı altında ülke çıkarları ile örtüşmeyen, hatta zaman zaman çelişen seçeneklerin peşine takılma çizgileri arasında sıkışıp kalmıştır. Özellikle son on yılda Türk dış politikasındaki önceliklerin değiştiğine, Türkiye'nin pasif dış politika gömleğini üzerinden çıkardığına tanıklık ediyoruz. 2002 yılından itibaren onu uluslararası sistemde düzen kurucu merkez bir ülke konumuna taşıyacak alt yapının inşa edildiği siyasi istikrar yanında kaydedilen ekonomik büyüme ve kalkınma Türkiye'nin kendine güvenini artırdı. Başbakan Recep Tayyip Erdoğan'ın sık sık altını çizdiği "kendine güven" vurgusu dış politika kararlarının alınmasında önemli bir dayanak oldu. Avrupa Birliği, ortak bir dış politika inşasında üyeleri arasındaki belirsizliklerle ve ekonomik krizlerle mücadele ederken, ABD başlattığı ve sürdürdüğü savaşların aşındırdığı imajını tamir etme çabası sürdürürken, Türkiye kaybettiği yılları Afrika, Balkanlar ve Güney Amerika açılımlarıyla telafi etmeyi başardı. Stratejik derinlik, merkez ve düzen kurucu ülke olmak, komşularla sıfır sorun, proaktif dış politika gibi kavramları siyasete dönüştüren ve uygulamaya koyan yeni Türk dış politikasının tasarımcısı Dışişleri Bakanı Ahmet Davutoğlu, gündemi takip eden değil önceden belirleyen bir liderlik sergilemektedir. Dış politika tutumlarına göre ülkeler iddialı ve iddiasız olarak basitçe ikiye ayrılabilir. Tahmin edileceği üzere ikinci grup hayli kalabalık olduğu halde, birinci gruba ABD gibi, Rusya gibi, Çin gibi sayılı ülkeler girer... Türkiye'nin son on yılda izlediği dış politika tutumu ve hamleleri ikinci gruptan çıkıp birinci gruba girme çabası içinde değerlendirilebilir. Türkiye’nin tarihi, coğrafyası, sahip olduğu kültürel değerler onu böyle bir konuma doğal olarak itmekle beraber, Dışişleri Bakanı Ahmet Davutoğlu’nun danışman olduğu dönemden beri savunduğu ''stratejik derinlik'' felsefesi bu kabul üzerine oturuyor. Türkiye'nin getirmiş olduğu yeni dış politika anlayışı sayesinde bölgesinde artan jeoekonomik etkinliğini hisseden Arap ülkeleri, komşularla sıfır problem modelinin açmış olduğu fırsat alanlarına nüfus etmeye başlamışlardır. Türkiye, Ürdün, Lübnan ve Suriye'yi içine alan Yüksek Düzeyli Stratejik İşbirliği Konseyi tesis edilmesi ve bu ülkeler arasında serbest ticaret ve dolaşım alanı oluşturulması ve vizelerin kaldırılmasının altında bahsetmiş olduğumuz yeni güvenlik kültürünün dinamizmi yatmaktadır. Bu tür girişimler ilişkilerin doğasını sıfır toplamlı oyun politikasından kazan kazan politikasına dönüştürmektedir. Özellikle ülkeler arası ekonomik bağımlılığın artması ise bizi ilerde yaşanacak olan bölgesel krizlerin çabuk ve düşük maliyetlerle aşılmasını sağlayacak mekanizmalar geliştirmesine zemin hazırlayacak ve potansiyel çatışma alanlarının devreye girme ihtimalini miminuma çekecektir. Bu anlamda Türkiye'nin son dönemde jeo-ekonomik anlamda kazanmış olduğu dinamizmin bölgesel aktörler tarafından dikkatle izlendiği bilinmektedir.
Nanobiomaterials in Drug Delivery: Applications of Nanobiomaterials presents novel approaches regarding nanostructured drug delivery systems, revealing the most investigated materials for the development of particular nanobioshuttles. This book brings the results of current research to reach those who wish to use this knowledge in an applied setting, providing one coherent text, with focused chapters and easily accessible information. At its core, it is a collection of titles, bringing together many of the novel applications these materials have in biology, also discussing the advantages and disadvantages of each application and the perspectives of the technologies based on these findings. At the moment, there is no other comparable book series covering all the subjects approached in this set of titles. - Provides up-to-date and well-structured reference material for students, researchers, and practitioners working in the biomedical, biotechnological, and engineering fields - Presents a valuable guide to recent scientific progress, along with most known applications of nanomaterials in the biomedical area - Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine/nanobiology
This book provides a comprehensive survey of the exercise of political power and justice in the Middle East from ancient Mesopotamia through into the 20th century, through a detailed examination of "the Circle of Justice". A "must read" for students, policymakers, and ordinary citizens, this book will be an important contribution to the areas of political history, political theory, Middle East studies and Orientalism.
Multifunctional Systems for Combined Delivery, Biosensing, and Diagnostics explores how multifunctional nanocarriers are being used in combined delivery and diagnostics in contemporary medicine. Particular attention is given to efforts to i) reduce the side effects of therapeutic agents, ii) increase the pharmacological effect, and iii) improve aqueous solubility and chemical stability of different therapeutic agents. The chapters focus on applications of nanostructured materials and nanocarriers, highlighting how these can be used effectively in both diagnosis and delivery. This applied focus makes the book an important reference source for those wanting to learn more about how specific nanomaterials and nanotechnology systems can help to solve drug delivery and diagnostics problems. This book is a valuable resource for materials scientists, bioengineers, and medical researchers who are looking for an applications-oriented guide on how nanotechnology and nanomaterials can be used effectively throughout the medical treatment process, from diagnosis to treatment. - Explores the benefits of using a variety of nanomaterials as drug delivery agents - Explains how nanocarriers can reduce the side effects of therapeutic agents - Provides an analysis of the pros and cons of using specific nanocarriers to solve particular diagnosis and delivery problems