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Americans have long recognized that investments in public education contribute to the common good, enhancing national prosperity and supporting stable families, neighborhoods, and communities. Education is even more critical today, in the face of economic, environmental, and social challenges. Today's children can meet future challenges if their schooling and informal learning activities prepare them for adult roles as citizens, employees, managers, parents, volunteers, and entrepreneurs. To achieve their full potential as adults, young people need to develop a range of skills and knowledge that facilitate mastery and application of English, mathematics, and other school subjects. At the same time, business and political leaders are increasingly asking schools to develop skills such as problem solving, critical thinking, communication, collaboration, and self-management - often referred to as "21st century skills." Education for Life and Work: Developing Transferable Knowledge and Skills in the 21st Century describes this important set of key skills that increase deeper learning, college and career readiness, student-centered learning, and higher order thinking. These labels include both cognitive and non-cognitive skills- such as critical thinking, problem solving, collaboration, effective communication, motivation, persistence, and learning to learn. 21st century skills also include creativity, innovation, and ethics that are important to later success and may be developed in formal or informal learning environments. This report also describes how these skills relate to each other and to more traditional academic skills and content in the key disciplines of reading, mathematics, and science. Education for Life and Work: Developing Transferable Knowledge and Skills in the 21st Century summarizes the findings of the research that investigates the importance of such skills to success in education, work, and other areas of adult responsibility and that demonstrates the importance of developing these skills in K-16 education. In this report, features related to learning these skills are identified, which include teacher professional development, curriculum, assessment, after-school and out-of-school programs, and informal learning centers such as exhibits and museums.
This book acts as a compilation of papers presented in the Human Engineering Symposium (HUMENS 2021). The symposium theme, “Human-centered Technology for A Better Tomorrow,” covers the following research topics: ergonomics, biomechanics, sports technology, medical device and instrumentation, artificial intelligence / machine learning, industrial design, rehabilitation, additive manufacturing, modelling and bio-simulation, and signal processing. Fifty-nine articles published in this book are divided into four parts, namely Part 1—Artificial Intelligence and Biosimulation, Part 2—Biomechanics, Safety and Sports, Part 3—Design and Instrumentation, and Part 4—Ergonomics.
Rev. ed. of: Media and culture. 2nd ed. c2000. Includes bibliographical references (p. 575-582) and index.
Well-known security experts decipher the most challenging aspect of cloud computing-security Cloud computing allows for both large and small organizations to have the opportunity to use Internet-based services so that they can reduce start-up costs, lower capital expenditures, use services on a pay-as-you-use basis, access applications only as needed, and quickly reduce or increase capacities. However, these benefits are accompanied by a myriad of security issues, and this valuable book tackles the most common security challenges that cloud computing faces. The authors offer you years of unparalleled expertise and knowledge as they discuss the extremely challenging topics of data ownership, privacy protections, data mobility, quality of service and service levels, bandwidth costs, data protection, and support. As the most current and complete guide to helping you find your way through a maze of security minefields, this book is mandatory reading if you are involved in any aspect of cloud computing. Coverage Includes: Cloud Computing Fundamentals Cloud Computing Architecture Cloud Computing Software Security Fundamentals Cloud Computing Risks Issues Cloud Computing Security Challenges Cloud Computing Security Architecture Cloud Computing Life Cycle Issues Useful Next Steps and Approaches
This volume focuses on a variety of in silico protocols of the latest bioinformatics tools and computational pipelines developed for neo-antigen identification and immune cell analysis from high-throughput sequencing data for cancer immunotherapy. The chapters in this book cover topics that discuss the two emerging concepts in recognition of tumor cells using endogenous T cells: cancer vaccines against neo-antigens presented on HLA class I and II alleles, and checkpoint inhibitors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Bioinformatics for Cancer Immunotherapy: Methods and Protocols is a valuable research tool for any scientist and researcher interested in learning more about this exciting and developing field.
Praise for the Second Edition: "The authors present an intuitive and easy-to-read book. ... accompanied by many examples, proposed exercises, good references, and comprehensive appendices that initiate the reader unfamiliar with MATLAB." —Adolfo Alvarez Pinto, International Statistical Review "Practitioners of EDA who use MATLAB will want a copy of this book. ... The authors have done a great service by bringing together so many EDA routines, but their main accomplishment in this dynamic text is providing the understanding and tools to do EDA. —David A Huckaby, MAA Reviews Exploratory Data Analysis (EDA) is an important part of the data analysis process. The methods presented in this text are ones that should be in the toolkit of every data scientist. As computational sophistication has increased and data sets have grown in size and complexity, EDA has become an even more important process for visualizing and summarizing data before making assumptions to generate hypotheses and models. Exploratory Data Analysis with MATLAB, Third Edition presents EDA methods from a computational perspective and uses numerous examples and applications to show how the methods are used in practice. The authors use MATLAB code, pseudo-code, and algorithm descriptions to illustrate the concepts. The MATLAB code for examples, data sets, and the EDA Toolbox are available for download on the book’s website. New to the Third Edition Random projections and estimating local intrinsic dimensionality Deep learning autoencoders and stochastic neighbor embedding Minimum spanning tree and additional cluster validity indices Kernel density estimation Plots for visualizing data distributions, such as beanplots and violin plots A chapter on visualizing categorical data
The book provides an overview on how the microbiome contributes to human health and disease. The microbiome has also become a burgeoning field of research in medicine, agriculture & environment. The readers will obtain profound knowledge on the connection between intestinal microbiota and immune defense systems, medicine, agriculture & environment. The book may address several researchers, clinicians and scholars working in biomedicine, microbiology and immunology. The application of new technologies has no doubt revolutionized the research initiatives providing new insights into the dynamics of these complex microbial communities and their role in medicine, agriculture & environment shall be more emphasized. Drawing on broad range concepts of disciplines and model systems, this book primarily provides a conceptual framework for understanding these human-microbe, animal-microbe & plant-microbe, interactions while shedding critical light on the scientific challenges that lie ahead. Furthermore this book explains why microbiome research demands a creative and interdisciplinary thinking—the capacity to combine microbiology with human, animal and plant physiology, ecological theory with immunology, and evolutionary perspectives with metabolic science.This book provides an accessible and authoritative guide to the fundamental principles of microbiome science, an exciting and fast-emerging new discipline that is reshaping many aspects of the life sciences. These microbial partners can also drive ecologically important traits, from thermal tolerance to diet in a typical immune system, and have contributed to animal and plant diversification over long evolutionary timescales. Also this book explains why microbiome research presents a more complete picture of the biology of humans and other animals, and how it can deliver novel therapies for human health and new strategies.
According to the American Cancer Society, more than 1.6 million people will be diagnosed with cancer during this year. Outcomes have steadily risen over the last several decades with the advent of newer therapies. As outcomes have improved, more and more cancer patients are developing critical illness. In the not-too-distant past, patients with active malignancy were thought not appropriate for critical care services as decreased longevity related to the cancer suggested poor prognosis for intensive care utilization. More recently, evidence supports rapid activation of critical care services leading to improved outcomes in cancer patients. Moreover, just as sub-subspecialty critical care experience in trauma and neurosciences has proved beneficial, the emerging field of oncology critical care warrants specific attention.