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The joint FAO/WHO Codex Alimentarius Commission is the UN body responsible for establishing international food standards aimed at protecting the health of consumers and ensuring fair practices in the food trade. This publication contains the overarching principles on the risk analysis of foods derived from modern biotechnology and guidelines for food safety assessment of foods derived from recombinant-DNA plants or produced using recombinant-DNA micro-organisms, as adopted by the Commission at its 26th session, held in 2003.
The texts in this publication represent the outcome of the work of the Codex Alimentarius Commission on principles and guidelines for food safety assessment of foods derived from modern biotechnology. They give guidance on how to assess the safety of such foods and thus protect the health of consumers. This second edition includes texts adopted by the Codex Alimentarius Commission up to 2008. Also published in French and in Spanish.
This Workshop was established primarily to address the question of what strategies can be used to establish the safety of food produced by biotechnology if there is no acceptable counterpart for comparison. Workshop presentations discussed the construction of safe recombinant wine yeast strains; safety approaches to pure culture fermentation of vegetables; food safety assessment of transgenic insect-resistant Bt tomatoes; evaluation of toxicological studies on Flavr Savr tomato; safety evaluation of glyphosate-tolerant soybeans; food safety evaluation of a transgenic squash; evaluation of strategies for food safety assessment of genetically modified agricultural products; limitations of whole food feeding studies in food safety assessment; toxicological testing of novel foods; dietary assessment related to the safety evaluation of foods; the role of databases; the use of in vivo and in vitro models in the testing of microorganisms; the application of human-type diets in rodent feeding studies for the safety evaluation of novel foods; investigations of the allergenicity of Brazil nut 2S seed storage protein in transgenic soybean; U.S. EPA considerations for mammalian health effects presented by transgenic plant pesticides; etc.
The rapid progress of modern biotechnology has given rise to new legislative needs in order to safeguard human health and the environment while at the same time taking advantage of the opportunities offered by biotechnology. Recent years have seen important new legislation being adopted and older law amended in order to respond to the new challenges. The purpose of this study is to indicate the extent to which international agreements and a small selected group of national laws may already be assisting societies to realize modern biotechnology's potential and avoid its possible risks.
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
Presents the conclusions of an international group of experts convened by FAO and WHO to consider strategies and procedures for assessing the safety of food produced by biotechnology. The Consultation reviewed the current and potential applications of biotechnology to food production and formulated a number of recommendations; for example, it considered that, from the point of view of safety, there was no fundamental difference between traditional products and contemporary ones obtained by means of biotechnology, and that any safety assessment should be based on the molecular, biological, and chemical characteristics of the material to be assessed.