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Magnetic resonance systems are used in almost every academic and industrial chemistry, physics and biochemistry department, as well as being one of the most important imaging modalities in clinical radiology. The design of such systems has become increasingly sophisticated over the years. Static magnetic fields increase continuously, large-scale arrays of receive elements are now ubiquitous in clinical MRI, cryogenic technology has become commonplace in high resolution NMR and is expanding rapidly in preclinical MRI, specialized high strength magnetic field gradients have been designed for studying the human connectome, and the commercial advent of ultra-high field human imaging has required new types of RF coils and static shim coils together with extensive electromagnetic simulations to ensure patient safety. This book covers the hardware and engineering that constitutes a magnetic resonance system, whether that be a high-resolution liquid or solid state system for NMR spectroscopy, a preclinical system for imaging animals or a clinical system used for human imaging. Written by a team of experts in the field, this book provides a comprehensive and instructional look at all aspects of current magnetic resonance technology, as well as outlooks for future developments.
This book presents a comprehensive treatment of electromagnetic analysis and design of three critical devices for an MRI system - the magnet, gradient coils, and radiofrequency (RF) coils. Electromagnetic Analysis and Design in Magnetic Resonance Imaging is unique in its detailed examination of the analysis and design of the hardware for an MRI system. It takes an engineering perspective to serve the many scientists and engineers in this rapidly expanding field. Chapters present: an introduction to MRI basic concepts of electromagnetics, including Helmholtz and Maxwell coils, inductance calculation, and magnetic fields produced by special cylindrical and spherical surface currents principles for the analysis and design of gradient coils, including discrete wires and the target field method analysis of RF coils based on the equivalent lumped-circuit model as well as an analysis based on the integral equation formulation survey of special purpose RF coils analytical and numerical methods for the analysis of electromagnetic fields in biological objects With the continued, active development of MRI instrumentation, Electromagnetic Analysis and Design in Magnetic Resonance Imaging presents an excellent, logically organized text - an indispensable resource for engineers, physicists, and graduate students working in the field of MRI.
The foundation for understanding the function and dynamics of biological systems is not only knowledge of their structure, but the new methodologies and applications used to determine that structure. This volume in Biological Magnetic Resonance emphasizes the methods that involve Ultra High Field Magnetic Resonance Imaging. It will interest researchers working in the field of imaging.
This book describes the design of the first functioning single-sided tomograph, the related measurement methods, and a number of applications in medicine, materials science, and chemical engineering. It will be the first comprehensive account of this new device and its applications. Among the key advances of this method is that images can be obtained in much shorter times than originally anticipated, and that even vector maps of flow fields can be measured although the magnetic fields are highly inhomogeneous. Furthermore, the equipment is small, mobile and affordable to small and medium enterprises and can be located in doctors’ offices.
Magnetic Resonance Spectroscopy is known as a valuable diagnostic tool for physicians as well as a research tool for biochemists. In addition to hydrogen (which is the most abundant atom with nuclear magnetic resonance capability), other species (such as 31P or 13C) are used as well, to obtain certain information such as metabolite concentrations in neural or muscular tissues. However, this requires nuclear magnetic resonance (NMR) transmitter/receivers (coils) capable of operating at multiple frequencies, while maintaining a good performance at each frequency. The objective of this work is to discuss various design approaches used for second-nuclei RF (radio frequency) coils, and to analyze the performance of a particular design, which includes using inductor-capacitor (LC) trap circuits on a 31P coil. The method can be easily applied to other nuclei. The main advantage of this trapping method is the enabling design of second-nuclei coils that are insertable into standard proton coils, maintaining a near-optimum performance for both nuclei. This capability is particularly applicable as MRI field strengths increase and the use of specialized proton coils becomes more prevalent. A thorough performance analysis shows the benefit of this method over other designs, which usually impose a significant signal-to-noise (SNR) sacrifice on one of the nuclei. A methodology based on a modular coil configuration was implemented, which allowed for optimization of LC trap decoupling as well as performance analysis. The 31P coil was used in conjunction with various standard 1H coil configurations (surface/volume/array), using the trap design to overcome the coupling problem (degraded SNR performance) mentioned above. An analytical model was developed and guidelines on trap design were provided to help optimize sensitivity. The performance was analyzed with respect to the untrapped case, using RF bench measurements as well as data obtained from the NMR scanner. Insertability of this coil design was then verified by using it with general-purpose proton coils available. Phantoms were built to mimic the phosphorus content normally found in biologic tissues in order to verify applicability of this coil for in vivo studies. The contribution of this work lies in the quantification of general design parameters to enable "insertable" second-nuclei coils, in terms of the effects on SNR and resonance frequency of a given proton coil.
​Within the past few decades MRI has become one of the most important imaging modalities in medicine. For a reliable diagnosis of pathologies further technological improvements are of primary importance. This study deals with a radically new approach of image encoding. Gradient linearity has ever since been an unquestioned technological design criterion. With the advent of parallel imaging, this approach may be questioned, making way of much a more flexible gradient hardware that uses encoding fields with an arbitrary geometry. The theoretical basis of this new imaging modality – PatLoc imaging – are comprehensively presented, suitable image reconstruction algorithms are developed for a variety of imaging sequences and imaging results – including in vivo data – are explored based on novel hardware designs.
New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.
This book is about pulse nuclear magnetic resonance (NMR), with its techniques, the information to be obtained, and practical advice on performing experiments. The emphasis is on the motivation and physical ideas underlying NMR experiments and the actual techniques, including the hardware used. The level is generally suitable for those to whom pulse NMR is a new technique, be they students in chemistry or physics on the one hand and research workers in biology, geology, or agriculture, on the other. The book can be used for a senior or first year graduate course where it could supplement the standard NMR texts.