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Immunogenetics is a 12-chapter book that begins with the elucidation of the major histocompatibility complex genes and their role in autoimmune and infectious diseases. Subsequent chapters explore the human major histocompatibility complex, including implications of their complement genes for linkage disequilibrium and disease associations. This book also describes the genetics of human immunoglobulins; T-cell clones; genes of the major histocompatibility complex of the mouse; and the generation, characterization, and use of monoclonal antibodies of murine and human origin. Specific diseases are also discussed; these include spondoarthritides, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and autoimmune thyroid disease. This book will be of beneficial value to specialists in infectious diseases, endocrinology, connective tissue diseases, and neurology, as well as to medical scientists in immunology and molecular biology.
A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology. - Contains exclusive information about research on immunogenetics from around the globe - Includes minute and recent details that will be the prerequisite requirement for any researcher who wants to work on immunogenetics and its applications - Comes fully-equipped with pictures, illustrations and tables that deliver information in a meticulous manner
This atlas describes and illustrates the pathology of solid organ transplants and includes chapters covering transplant pathology of the kidney, lung, heart, liver, pancreas, small bowel and limbs. Each of these chapters briefly reviews the latest rejection classifications for each organ system with explanatory notes highlighting diagnostic criteria, and tables listing entities in the differential diagnosis. Included with each chapter are images demonstrating the pathology of the most common and important diseases, especially patterns of organ rejection and related entities or mimickers. Examples of classic disease processes are provided, as well as atypical presentations that may highlight and prevent diagnostic pitfalls. A comprehensive explanation of the immunogenetics of transplant rejection is included, enabling the general pathologist to become familiar with the most important aspects of serologic testing in this patient population. A review of post-transplant lymphoproliferative diseases is also provided. Practical Atlas of Transplant Pathology is aimed at both general and expert pathologists who encounter transplant pathology specimens in their practice.
The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field.
Advances in Immunology
Current Advances in Immunology presents the advances in immunology in an easy-to-use format. The book is split into 51 main areas that are further classified into sections. Where appropriate, cross-referencing to other sections is given. The text also provides a guide on how to use the book. Papers included in the book focus on a variety of topics ranging from immunoglobulins and antigens to interferons, lymphocytes, leukocytes, and macrophages as well as natural killer cells, Langerhans cells, dendritic cells, lymphoid tissue, and humoral mediators of immune responses and immunomodulators. Other papers discuss blood groups, transplantation, anti-bacterial immunity, chronic inflammation, delayed hypersensitivity, and contact sensitivity. Immunodeficiency, immune complexes, tumor immunity, immunopharmacology and immunotoxicology, and the link between nutrition and immunity are also explored. A section devoted to psychoneuroimmunology focuses on the effect of stress on graft-versus-host reaction; immunological response to stress in agoraphobia and panic attacks; and anti-beta-endorphin immunoglobulin G in humans. This book will be of interest to working scientists in the field of immunology.
The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. - With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far - Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors - Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resources available for carrying out such research