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Continuous Cultivation of Microorganisms deals with research studies on the continuous processes in cultivation and their applications in industrial production. Divided into 40 chapters, the book is composed of contributions of authors who have conducted extensive studies on continuous cultivation. The discussions start with situations and trends in the advancement of continuous cultivation, multi-stage continuous culture, the theory of multi-stage continuous cultures, and a stochastic model of continuous cultivation of microorganisms in several vessels. This discussion is followed by the presentation of the theory of continuous fermentation; the use of continuous culture method for analyzing cell functions; and a comparative study of cell mass production in a single and multistage cultivation. The book goes further with discussions on soil microbiology and the processes and environments involved in the culture of bacteria. The text also presents the fermentation processes of beer, lactic acid, alcohol, and liquor. The discussions are supported by methods, experiments, and numerical representations. The book also discusses electronic programs or automatic controls involved in fermentation processes. The selection is a vital source of data for those who are interested in conducting research on continuous cultivation.
Allen I. Laskin Biosciences Research Exxon Research and Engineering Company Linden, New Jersey I was contacted in the Fall of 1981 by Professors Martin Dworkin and Palmer Rogers, of the University of Minnesota and asked to participate in the orgnization of the 1983 conference in the series, "Interface Between Biology and Medicine". They and the other members of the advisory committee had the vision to realize that this was a time to depart somewhat from the traditional theme, since one of the major areas of interest in the biological and related sciences these days is that of biotechnology in a broader sense than its impact on medicine alone. In designing the format of the Conference, we considered another factor. There has been a plethora of conferences, symposia, and meetings on biotechnology over the past few years, and the faces and topics have become rather familiar. There has been a strong emphasis on the development of the technology and the "biotechnology industry"; less attention has been paid to the science behind it. One might get the impression from some of these meetings and from the popular press that biotechnology has just recently sprung up, apparently full blown; the very fundamental scientific discoveries and the great body of 1 ALLEN I. LASKIN 2 continuing research that forms that basis for the technology is often obscured.
Traditionally, symbiosis research has been undertaken by researchers working independently of one another and often focused on a few cases of bipartite host-symbiont interactions. New model systems are emerging that will enable us to fill fundamental gaps in symbiosis research and theory, focusing on a broad range of symbiotic interactions and including a variety of multicellular hosts and their complex microbial communities. In this Research Topic, we invited researchers to contribute their work on diverse symbiotic networks, since there are a large variety of symbioses with major roles in the proper functioning of terrestrial or aquatic ecosystems, and we wished the Topic to provide a venue for communicating findings across diverse taxonomic groups. A synthesis of recent investigations in symbiosis can impact areas such as agriculture, where a basic understanding of plant-microbe symbiosis will provide foundational information on the increasingly important issue of nitrogen fixation; climate change, where anthropogenic factors are threatening the survival of marine symbiotic ecosystems such as coral reefs; animal and human health, where unbalances in host microbiomes are being increasingly associated with a wide range of diseases; and biotechnology, where process optimization can be achieved through optimization of symbiotic partnerships. Overall, our vision was to produce a volume of works that will help define general principles of symbiosis within a new conceptual framework, in the road to finally establish symbiology as an overdue central discipline of biological science.
Recent Advances in Animal Nutrition — 1987 focuses on the advancement of techniques, procedures, and processes in animal nutrition. The selection first discusses techniques for identifying the metabolizable energy (ME) content of poultry feeds and the impact of declaration of ME value of poultry feeds. Methods for determining the ME of feeds; formulation of products and declaration of energy; species and ages of birds; and analytical problems are considered. The book also discusses the effects of diarrhea and wet litter in meat poultry; the inclusion of phosphorus in the diet of laying hens; natural products for egg yolk pigmentation; and the addition of enzymes to enhance the utilization of pig and poultry diets. The text also examines the nutrition of goats and cattle; immunity, nutrition, and performance in animal production; and methods of identifying the amino acid requirement of pigs. The book highlights as well the reactions of consumers to meat quality. Consumption trends; changes in eating patterns, retailing, and consumer purchasing patterns; and fatness and eating quality are considered. The book is a good source of information for readers wanting to study animal nutrition.
Optimization of Pharmaceutical Processes presents contributions from leading authorities in the fields of optimization and pharmaceutical manufacturing. Formulated within structured frameworks, practical examples and applications are given as guidance to apply optimization techniques to most aspects of pharmaceutical processes from design, to lab and pilot scale, and finally to manufacturing. The increasing demand for better quality, higher yield, more efficient-optimized and green pharmaceutical processes, indicates that optimal conditions for production must be applied to achieve simplicity, lower costs and superior yield. The application of such methods in the pharmaceutical industry is not trivial. Quality of the final product is of major importance to human health and the need for deep knowledge of the process parameters and the optimization of the processes are imperative. The volume, which includes new methods as well as review contributions will benefit a wide readership including engineers in pharmaceuticals, chemical, biological, to name just a few.
Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.
Nematodes are microscopic, eel-like roundworms that can infect humans, animals, and plants and cause serious damage and yield losses in a wide range of crops worldwide. This book includes thirteen chapters that address such topics as diagnosing nematode infections in crops (fruits and horticultural crops), management and biological control of plant-parasitic nematodes, biological indicators of nematodes, and entomopathogenic and marine nematodes. This comprehensive volume is a useful resource for students, teachers, researchers, field workers, and all those interested in and working with nematodes.