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This book focuses on the basic aspects of dental stem cells (DSCs) as well as their clinical applications in tissue engineering and regenerative medicine. It opens with a discussion of classification, protocols, and properties of DSCs and proceeds to explore DSCs within the contexts of cryopreservation; epigenetics; pulp, periodontal, tooth, bone, and corneal stroma regeneration; neuronal properties, mesenchymal stem cells and biomaterials; and as sources of hepatocytes for liver disease treatment. The fifteen expertly authored chapters comprehensively examine possible applications of DSCs and provide invaluable insights into mechanisms of growth and differentiation. Dental Stem Cells: Regenerative Potential draws from a wealth of international perspectives and is an essential addition to the developing literature on dental stem cells. This installment of Springer’s Stem Cell Biology and Regenerative Medicine series is indispensable for biomedical researchers interested in bioengineering, dentistry, tissue engineering, regenerative medicine, cell biology and oncology.
Covering the functional and esthetic needs of edentulous patients, Prosthodontic Treatment for Edentulous Patients: Complete Dentures and Implant-Supported Prostheses, 13th Edition helps you provide complete dentures, with and without dental implant support. It addresses both the behavioral and clinical aspects of diagnosis and treatment and covers treatment modalities including osseointegration, overdentures, implant-supported fixed prosthesis, and the current and future directions of implant prosthodontics. New to this edition are full-color photographs and coverage of immediately loaded complete dental prostheses. From lead editor and respected educator George Zarb, Prosthodontic Treatment for Edentulous Patients provides an atlas of clinical procedures and emphasizes the importance of evidence-based treatment. - Short, easy-to-read chapters cover the essentials of care for both short- and long-term patients, stressing the importance of evidence-based treatment. - Expanded coverage of implant prosthodontics addresses the clinical protocols for implant-retained and implant-supported prosthodontic management. - Specific chapters address the three surfaces of the complete denture: (1) an impression or intaglio surface, (2) a polished surface, and (3) an occlusal surface, the integration of which is crucial to creating a stable, functional, and esthetic result. - Chapter on health and nutrition examines a number of systemic conditions (vesciculoerosive conditions, systemic lupus erythematosus, burning mouth syndrome, salivary dysfunction, Sjögren's syndrome, hyper/hyposalivation, diabetes) that affect the oral cavity and specifically influence the prognosis for wearing complete dentures or for accepting osseointegrated prostheses. - Chapter on the time-dependent changes which occur in the oral cavity focuses on both time-related direct (ulcer/cheek biting, irritation hyperplasia, denture stomatitis, flabby ridge and pendulous maxillary tuberosities, hyperkeratosis and oral cancer, residual ridge reduction) and indirect (atrophy of masticatory muscles, nutritional status and masticatory function, control of sequelae) changes in the oral environment, and provides strategies to minimize the risk of such changes. - Chapter on the techniques used to prolong the life of complete dentures focuses on the two techniques used to extend the life of dentures: relining and rebasing, also touching on denture duplication. - Well-respected editors and contributors are the leaders in their field, lending credibility and experience to each topic.
Many of the systemic autoimmune diseases seen in children are different from those seen in adults making them a special problem for physicians and scientists who care for the affected children and study their diseases. Benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties, this volume covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices.
Corresponding chapter-by-chapter to Medical-Surgical Nursing, 9e, Elsevier Adaptive Learning combines the power of brain science with sophisticated, patented Cerego algorithms to help you learn faster and remember longer. It's fun; it's engaging; and it's constantly tracking your performance and adapting to deliver content precisely when it's needed to ensure core information is transformed into lasting knowledge. Please refer to the individual product pages for the duration of access to these products. An individual study schedule reduces cognitive workload and helps you become a more effective learner by automatically guiding the learning and review process. The mobile app offers a seamless learning experience between your smartphone and the web with your memory profile maintained and managed in the cloud. UNIQUE! Your memory strength is profiled at the course, chapter, and item level to identify personal learning and forgetting patterns. UNIQUE! Material is re-presented just before you would naturally forget it to counteract memory decay. A personalized learning pathway is established based on your learning profile, memory map, and time required to demonstrate information mastery. The comprehensive student dashboard allows you to view your personal learning progress.
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.
Get the essential information you need to master radiographic pathology! Radiographic Pathology for Technologists, 8th Edition introduces the pathologic appearance of common diseases as seen in diagnostic imaging. Organized by body system, the book uses a clear, easy-to-understand approach to discuss anatomy and physiology, the pathologic process, signs and symptoms, diagnosis, and treatment of diseases. This edition is updated to reflect today's radiography practice including diagnostic modalities such as CT, MR, sonography, nuclear medicine, and fusion/hybrid imaging. From well-known radiologic and imaging sciences author Nina Kowalczyk, this essential text also provides excellent preparation for the radiographic pathology portion of the ARRT® credentialing exam. - Essential level of coverage presents approximately 150 injuries and abnormalities most frequently diagnosed using medical imaging, focusing students on the pathologies they are most likely to encounter in practice and providing just the right amount of information for a shorter pathology course. - Discussions of correlative and differential diagnosis explain the diagnostic process and demonstrate the importance of high-quality images. - Summary tables review the pathologies covered and the preferred imaging modalities for diagnosis. - Learning features include chapter outlines and objectives, key terms, and multiple-choice and discussion questions for each chapter, with answers provided in the back of the text. - NEW! Updated content reflects the latest ARRT and ASRT curriculum guidelines. - NEW! Current digital radiography is covered throughout the text. - NEW! Updated images and illustrations reflect current practice for general radiography and alternative modalities such as CT, MR, sonography, nuclear medicine, and fusion/hybrid imaging, demonstrating how pathologies appear in various imaging modalities.
Designed for portability, this clinical companion provides at-a-glance access to the information you need for more than 200 medical-surgical conditions and procedures. Completely updated content mirrors the revisions in the new 11th edition of Lewis’s main text: Medical-Surgical Nursing: Assessment and Management of Clinical Problems. This clinical companion is organized alphabetically for quick reference and includes a variety of full-color illustrations, summary tables, and a handy reference appendix full of laboratory values, Spanish translations of key phrases, and other information commonly used in nursing practice. Consistent and practical information covers definitions and descriptions, pathophysiology, clinical manifestations, complications, diagnostic studies, interprofessional care and drug therapy, and nursing management. Treatments and Procedures section summarizes the need-to-know content about common medical-surgical treatments and procedures such as basic life support, enteral nutrition, and artificial airway management. Handy reference appendix contains information commonly used in nursing practice, including laboratory values, commonly used formulas, Spanish translations of key phrases, and much more. Patient and caregiver teaching content is highlighted with a special icon to identify appropriate information to share with patients and caregivers about the care of various conditions. Cross-references to the Lewis main text identify how to access more in-depth information. Attractive four-color design makes it easy to locate specific information within the clinical companion. NEW! Updated content reflects the revisions and updates in Lewis’s Medical-Surgical Nursing, 11th Edition main text.
The fifth edition of 'Radiographic Pathology for Technologists' concisely describes and illustrates the pathological processes that radiographers are most likely to encounter.