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In recent years the pace of research in prostate cancer has increased dramatically. Creative ideas in combination with new and emerging technologies have led to an explosion of discovery. These types of advances in prostate cancer research presage an era of new treatment strategies based on an understanding of the cellular and molecular mechanisms of disease. In creating this book, we aimed to cover a broad "bench to bedside" research spectrum ranging from: genetic, molecular and cellular analyses to epidemiological studies, refinements in local treatment strategies and new biologically based non-hormonal treatments for systemic disease. Researchers and clinicians will find in this book a group of timely and clinically relevant chapters on prostate cancer research and treatment.
This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.
The MediFocus Guidebook on Prostate Cancer is the most comprehensive, up-to-date source of information available. You will get answers to your questions, including risk factors of Prostate Cancer, standard and alternative treatment options, leading doctors, hospitals and medical centers that specialize in Prostate Cancer, results of the latest clinical trials, support groups and additional resources, and promising new treatments on the horizon. This one of a kind Guidebook offers answers to your critical health questions including the latest treatments, clinical trials, and expert research; high quality, professional level information you can trust and understand culled from the latest peer-reviewed journals; and a unique resource to find leading experts, institutions, and support organizations including contact information and hyperlinks. This Guidebook was updated on February 2, 2012.
Although much has been written on surgical treatment for prostate cancer, this is the first book to present a comprehensive review of the new non-surgical therapies currently available in the management of prostate disease. This volume provides a detailed account of the key areas of treatment including, screening, early diagnosis of malignant disease, and the application of hormonal therapies for advanced prostate cancer. A 'continuum' approach to the management of malignant prostate disease is emphasized throughout the text. The editors are recognised international, as opinion leaders in the field of prostate cancer. In this single volume they offer the first balanced account of the new molecular and hormonal therapies currently available in the management of prostate cancer. It is intended that this volume should become the primary source of reference for all those, either in research or clinical practice who have an interest in combination therapy and the non-surgical treatment of prostate cancer. This book is published in full colour, with illustrations by Dee Mclean who is widely recognised as one of the leading medical artists working in this field.A unique feature of this volume is the inclusion of a CD.Rom which cross references to the text, providing a PowerPoint presentation, that also includes video clips, and animated graphics.
Prostate cancer is the most common type of cancer in men (other than skin cancer). Of all the men who are diagnosed with cancer each year, more than one-fourth have prostate cancer. This book includes within its scope the prevention, risk factors, symptoms, diagnosis, treatment, and rehabilitation of prostate cancer. Leading-edge scientific research from throughout the world is presented.
An important translational book bridging the gap between science and clinical medicine, Prostate Cancer reviews the biological processes that can be implicated in the disease, reviews current treatments, highlighting the pitfalls where relevant and examines the scientific developments that might result in novel treatments in the future. Key Features * Provides a translational resource for scientists and clinicians working on prostate cancer * Reviews current surgical interventions and highlights their related pitfalls * Presents the latest laparoscopic techniques with figures and illustrations of step-by-step procedures * Offers insight into the potential for novel approaches to treatment in the future * Includes personal perspectives from patients
Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. The authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer and into future, novel treatment strategies.
A Doody's Core Title 2012 Emerging Cancer Therapeutics is a trinary, hard cover, periodical that is designed to provide an up-to-date evidence-based review of a dedicated emerging cancer therapy topic of interest to clinicians and scientists who are involved in the care of patients receiving cancer treatment. It will serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinical oncologists, radiation oncologists, surgical oncologists, cancer biologists, and interdisciplinary colleagues throughout the oncology spectrum. With contributions from experts across the United States and Canada, Prostate Cancer details the current management of prostate cancer and reviews new therapies in development for prostate cancer, with an emphasis on castration-resistant prostate cancer (CRPC). Coverage includes discussion of multiple new agents that have been shown to impact overall survival or improve skeletal-related events in metastatic CRPC as well as articles covering new data on screening and prevention, integration of surgery and radiation with newly emerging medical therapies, and coverage of the newest developments in immunotherapy. This book is a valuable tool for clinicians, nurses, researchers, medical students, residents, and fellows. Included in Prostate Cancer: Updates in Prostate Cancer Prevention Prostate Cancer Screening, 2011 Current Surgical Approaches to Primary Prostate Cancer Treatment Updates in Radiation Therapy for Prostate Cancer: Dose Matters An Update on Androgen-Deprivation Therapy for Advanced Prostate Cancer Novel Androgen Receptor Therapeutic Targets for Advanced Prostate Cancer New Understanding of Metabolic Complications of Androgen-Deprivation Therapy Current State of Docetaxel-Based Therapy in Castration-Resistant Prostate Cancer Second-Line Chemotherapy for Castration-Resistant Prostate Cancer Emerging Role of Immunotherapy in the Treatment of Prostate Cancer Novel Bone-Targeted Therapy in Metastatic Prostate Cancer Emerging Treatment Strategies for Metastatic Prostate Cancer: The Next Step Forward
In 'Journeys in Prostate Cancer Treatment Innovation, ' the forefront of scientific advancements meets the relentless drive to combat prostate cancer. This comprehensive collection of journal articles curates pioneering research and clinical studies, presenting the promising prospects in prostate cancer therapy. The book explores revolutionary treatments like Chimeric Antigen Receptor T cell (CAR-T) therapy, which exemplifies the intersection of immunotherapy and genetic engineering, despite its challenges in targeting solid tumors. It chronicles the potential of endocrine therapy in bolstering early intervention and the synergistic effects of combination treatments such as oncolytic adenoviruses with radiotherapy. Moreover, breakthrough technologies like gene therapy and novel agents such as caffeic acid phenethyl ester (CAPE) targeting PI3K/Akt pathways are thoroughly examined. Embracing multimodal approaches, this compilation goes beyond isolated treatments, advocating for integrated strategies that include modern diagnostics, personalized medicine, and advanced imaging techniques. The articles emphasize holistic treatment perspectives and the imperative of precision medicine, promising a future where prostate cancer is not a punitive diagnosis but a treatable condition. This compendium serves as both an insightful resource for professionals and a beacon of hope in the quest for efficient, patient-centric prostate cancer treatments. Quality Research Publishing is dedicated to making knowledge more accessible to the general public by curating a topical compilation of the latest research on various subjects and providing plain language summaries. Each of the articles in this book is available individually and digitally without cost. However, we believe it is important for the contextualizing and sharing of educational and scientific work to curate this research in a way that is understandable and helpful to the average person seeking deeper knowledge of a particular subject. The research articles compiled for this book were published under a permissive Creative Commons license, are in the public domain, or have no copyright restrictions, permitting their use in this book. If you have questions about the licensing of any article, please visit qualityresearchpublishing.com.