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The first Joint Services Workshop on Biological Mass Spectrometry was held 28-30 July 1997, at the Hyatt Regency, Baltimore, MD. The workshop was organized by the U.S. Army Edgewood Research, Development, and Engineering Center (ERDEC) and co-sponsored by the U.S. Navy and U.S. Air Force. The overall objective of the workshop was to bring together experts and practitioners for a review of the state-of-the-art in biological mass spectrometry and related technologies to serve as the basis for the generation of a program strategy for the development of next-generation biological mass spectrometers. Such mass spectrometer systems will have significant impact not only on chemical/biological defense but also on environmental and food monitoring, the health industry, and various research and industrial endeavors. The workshop addressed a range of issues related to the development of automated, integrated mass spectrometers based on leading edge methodologies for the characterization, analysis, and identification of biological materials. Particular attention was given to applications of electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI), interface of separation methods, biological sample handling/processing, and potential biomarker classes. These Proceedings compile summaries of a majority of technical presentations made during the conference portion of the workshop.
The first Joint Services Workshop on Biological Mass Spectrometry was held 28-30 July 1997, at the Hyatt Regency, Baltimore, MD. The workshop was organized by the U.S. Army Edgewood Research, Development, and Engineering Center (ERDEC)* and co-sponsored by the U.S. Navy and U.S. Air Force. The overall objective of the workshop was to bring together experts and practitioners for a review of the state-of-the-art in biological mass spectrometry and related technologies to serve as the basis for the generation of a program strategy for the development of next-generation biological mass spectrometers. Such mass spectrometer systems will have significant impact not only on chemical/biological defense but also on environmental and food monitoring, the health industry, and various research and industrial endeavors. The workshop addressed a range of issues related to the development of automated, integrated mass spectrometers based on leading edge methodologies for the characterization, analysis, and identification of biological materials. Particular attention was given to applications of electrospray ionization (ESI) and matrix-assisted laser desorption ionization (MALDI), interface of separation methods, biological sample handling/processing, and potential biomarker classes. These Proceedings compile summaries of a majority of technical presentations made during the conference portion of the workshop.
This is a comprehensive guide to single-stranded RNA phages (family Leviviridae), first discovered in 1961. These phages played a unique role in early studies of molecular biology, the genetic code, translation, replication, suppression of mutations. Special attention is devoted to modern applications of the RNA phages and their products in nanotechnology, vaccinology, gene discovery, evolutionary and environmental studies. Included is an overview of the generation of novel vaccines, gene therapy vectors, drug delivery, and diagnostic tools exploring the role of RNA phage-derived products in the revolutionary progress of the protein tethering and bioimaging protocols. Key Features Presents the first full guide to single-stranded RNA phages Reviews the history of molecular biology summarizing the role RNA phages in the development of the life sciences Demonstrates how RNA phage-derived products have resulted in nanotechnological applications Presents an up-to-date account of the role played by RNA phages in evolutionary and environmental studies
Scores of talented and dedicated people serve the forensic science community, performing vitally important work. However, they are often constrained by lack of adequate resources, sound policies, and national support. It is clear that change and advancements, both systematic and scientific, are needed in a number of forensic science disciplines to ensure the reliability of work, establish enforceable standards, and promote best practices with consistent application. Strengthening Forensic Science in the United States: A Path Forward provides a detailed plan for addressing these needs and suggests the creation of a new government entity, the National Institute of Forensic Science, to establish and enforce standards within the forensic science community. The benefits of improving and regulating the forensic science disciplines are clear: assisting law enforcement officials, enhancing homeland security, and reducing the risk of wrongful conviction and exoneration. Strengthening Forensic Science in the United States gives a full account of what is needed to advance the forensic science disciplines, including upgrading of systems and organizational structures, better training, widespread adoption of uniform and enforceable best practices, and mandatory certification and accreditation programs. While this book provides an essential call-to-action for congress and policy makers, it also serves as a vital tool for law enforcement agencies, criminal prosecutors and attorneys, and forensic science educators.
Comprehensive manual for understanding and carrying out marine mammal rescue activities for stranded seals, manatees, dolphins, whales, or sea otters.
A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.
Pollinators-insects, birds, bats, and other animals that carry pollen from the male to the female parts of flowers for plant reproduction-are an essential part of natural and agricultural ecosystems throughout North America. For example, most fruit, vegetable, and seed crops and some crops that provide fiber, drugs, and fuel depend on animals for pollination. This report provides evidence for the decline of some pollinator species in North America, including America's most important managed pollinator, the honey bee, as well as some butterflies, bats, and hummingbirds. For most managed and wild pollinator species, however, population trends have not been assessed because populations have not been monitored over time. In addition, for wild species with demonstrated declines, it is often difficult to determine the causes or consequences of their decline. This report outlines priorities for research and monitoring that are needed to improve information on the status of pollinators and establishes a framework for conservation and restoration of pollinator species and communities.
Indianapolis Monthly is the Circle City’s essential chronicle and guide, an indispensable authority on what’s new and what’s news. Through coverage of politics, crime, dining, style, business, sports, and arts and entertainment, each issue offers compelling narrative stories and lively, urbane coverage of Indy’s cultural landscape.