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Differences in physiology between men and women extend far beyond differences in reproductive functions. Medical literature abounds in descriptions of differences in prevalence, symptoms and severity of diseases between men and women including heart attack, rheumatic diseases, gastrointestinal disease and osteoporosis. Much of the information is descriptive rather than mechanistic and scattered throughout a variety of books, review articles and original papers. This book provides a single source that summarizes current basic mechanisms of gene/hormone interactions and their subsequent impact on physiological functions. It is an ideal source material to be used in training the next generation of physician/scientists who will develop a more individualized approach to prevention, diagnosis and therapeutic medical practice.
Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available. Provides a sweeping, organ-by-organ review of currently observed sex differences in animal models and human disease Explains how sex differences influence physiology and disease Provides the critical knowledge on sex differences for better understanding of prevention and treatment of diseases
The fourth volume of the Advances in Molecular and Cell Biology series. Cell biology is a rapidly-developing discipline, bringing together many separate biological sciences. The interrelations of cell structure and function at molecular and subcellular levels are the central theme of the series.
It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
The field of gender-specific medicine examines how normal human biology and physiology differ between men and women and how the diagnosis and treatment of disease differs as a function of gender. This revealing research covers various conditions that predominantly occur in men as well conditions that predominantly occur in women. Among the areas of greatest difference are cardiovascular disease, mood disorders, the immune system, lung cancer as a consequence of smoking, osteoporosis, diabetes, obesity, and infectious diseases. The Second Edition of Principles of Gender-Specific Medicine focuses on the essentials of gender-specific medicine and the current study of sex and gender differences in human physiology and pathophysiology. New section editors, new chapter authors, and new chapters have been added to reflect the most up-to-date clinical research and practice. Offers insight into how the gender-specific risks of one organ system’s disease affects the health of other organ systems Outlines the sex-specific differences of normal anatomy and physiology Illustrates the gender-specific features and quantifies "gender" and "sex" as risk factors across all major diseases Qualifies and analyzes the results of new drug therapies designed with gender-specific differences in mind: ex, hormone therapy in men and women for the prevention and treatment of cardiovascular disease All chapters progress translationally from the basic science to the clinical applications of gender-specific therapies, drugs, or treatments Sections on drug metabolism, aging, and meta-analysis of data incorporated into all disease-specific chapters
The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation. This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness. Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers! 2018 PROSE Awards - Winner, Award for Clinical Medicine: Association of American Publishers Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols
In most animals, from bees to bison, house flies to humans, it is possible to see at a glance whether an individual is male or female. How and why have these differences in appearance and behaviour developed and what are the nature and extent of the differences between men and women? This book reviews the latest molecular, genetic, hormonal, anatomical and behavioural data in a wide range of species in a series of lively and highly readable articles from the world's leading experts in this field. Such an overview has never before been attempted. It will have a wide appeal, especially to undergraduates and graduates in the biological and medical sciences, and will help to bridge the gap between those who study genes and molecules in the laboratory and those who study the behaviour of animals in the wild.
Neuroscientific research on emotion has developed dramatically over the past decade. The cognitive neuroscience of human emotion, which has emerged as the new and thriving area of 'affective neuroscience', is rapidly rendering existing overviews of the field obsolete. This handbook provides a comprehensive, up-to-date and authoritative survey of knowledge and topics investigated in this cutting-edge field. It covers a range of topics, from face and voice perception to pain and music, as well as social behaviors and decision making. The book considers and interrogates multiple research methods, among them brain imaging and physiology measurements, as well as methods used to evaluate behavior and genetics. Editors Jorge Armony and Patrik Vuilleumier have enlisted well-known and active researchers from more than twenty institutions across three continents, bringing geographic as well as methodological breadth to the collection. This timely volume will become a key reference work for researchers and students in the growing field of neuroscience.
This text explains the biological aspects of human sex by using direct and intriguing comparisons with the many variations in sexual systems among non-human organisms.
The Handbook of Sex Differences is a four-volume reference work assembled and written to assess sex differences in human traits (although findings regarding other species are also included). Based on the authors’ highly influential 2008 book Sex Differences, these volumes highlight important new research findings from the last decade and a half alongside earlier findings. Conclusions reached by meta-analyses are also included. In this, the work’s first volume, findings from thousands of studies are summarized regarding basic biology. Results having to do with sex ratios at birth and traits involving a wide range of bodily features are reported along with numerous complex aspects of biochemistry, neurology, and physical health. The eight chapters comprising Volume I are as follows: 1. Reproduction, Development, and Morphology 2. Anatomical and Physiological Factors 3. Bodily Fluids, Biochemicals, and Biochemical Receptors 4. The Brain: Structure and Functioning 5. Physical Health and Illness Factors 6. Responses to Physical and Chemical Environmental Factors 7. Responses to Stress and to Pain 8. Prenatal Factors The Handbook of Sex Differences is of significant importance for any researcher, student, or professional who requires a comprehensive resource on sex differences.