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This book is on ovulation induction and controlled ovarian stimulation which is an integral part of most infertility therapies like intrauterine insemination and in vitro fertilization. It would deal with causes of anovulation and indications for ovarian stimulation. This book deals with basics as well as current and advanced practices. It provides a step by step protocol for ovarian stimulation. It gives a clear understanding of the science of reproductive endocrinology behind these stimulation protocols and roadmaps the latest therapies, defining their current relevance to treatment. Besides the practical guidance it also covers latest research work done in this field. In this day of information overload it is an attempt to integrate relevant information in a manner which can be applied in infertility practice in evidence based manner, making it rational, logical and rewarding for the reader.
The specialty of fertility preservation offers patients with cancer, who are rendered infertile by chemo- and radiotherapy, the opportunity to realize their reproductive potential. This gold-standard publication defines the specialty. The full range of techniques and scientific concepts is covered in detail, and the author team includes many of the world's leading experts in the field. The book opens with introductions to fertility preservation in both cancer and non-cancer patients, followed by cancer biology, epidemiology and treatment, and reproductive biology and cryobiology. Subsequent sections cover fertility preservation strategies in males and females, including medical/surgical procedures, ART, cryopreservation and transplantation of both ovarian tissue and the whole ovary, and in-vitro follicle growth and maturation. Concluding chapters address future technologies, as well as ethical, legal and religious issues. Richly illustrated throughout, this is a key resource for all clinicians specializing in reproductive medicine, gynecology, oncology, hematology, endocrinology and infertility.
VOLUME 1: INFERTILITY SECTION 1: ANATOMY AND PHYSIOLOGY 1. Anatomy of the Reproductive System 2. Regulation and Physiology of Menstrual Cycle 3. Oogenesis and Folliculogenesis 4. Spermatogenesis 5. Fertilization and Embryogenesis 6. Implantation 7. Embryo Endometrial Crosstalk and Endometrial Receptivity SECTION 2: REPRODUCTIVE ENDOCRINOLOGY 8. Synthesis and Metabolism of Steroid Hormones 9. Puberty and Aberrations 10. Amenorrhea 11. Endocrine Disorders Affecting Reproduction 12. Hirsutism 13. Luteal Phase Defect 14. Anovulation 15. Declining Fertility SECTION 3: COMBINED TOPICS 16. Evaluation of Infertility 17. Immunology and Infertility 18. Cytogenetics and Subfertility 19. Obesity and Infertility 20. Unexplained Infertility 21. Fertility Preservation 22. Counseling in Infertility 23. Assisted Reproductive Technology in Patients with Chronic Medical Disorders SECTION 4: MALE INFERTILITY 24. Etiopathogenesis of Male Infertility 25. Clinical and Endocrinological Evaluation of Infertile Male 26. Sexual Dysfunction in Male Infertility 27. Ultrasound in Male Infertility 28. Medical Management of Male Infertility 29. Azoospermia: Evaluation and Management 30. Varicocele and Infertility 31. Spinal Cord Injuries and Male Infertility 32. Algorithms for Genetic Evaluation of Infertile Males SECTION 5: FEMALE FACTOR INFERTILITY 33. Uterine Factors in Infertility 34. Tubal Factors in Infertility 35. Infections and Infertility 36. Tuberculosis and Infertility 37. Sonoendocrinology and Cycle Monitoring Assisted Reproduction Technology 38. Transvaginal Ultrasound and Doppler in Infertility 39. Polycystic Ovary Syndrome 40. Assessment of Ovarian Reserve 41. Endometriosis 42. Endoscopy in Infertility 43. Reconstructive Surgeries Enhancing Fertility SECTION 6: INTRAUTERINE INSEMINATION 44. Intrauterine Insemination 45. Optimizing Success in Intrauterine Insemination SECTION 7: OVARIAN STIMULATION 46. Drugs for Ovarian Stimulation 47. Ovulation Induction and Ovarian Stimulation Protocols 48. Role of Adjuvants in Ovarian Stimulation 49. Gonadotropinreleasing Hormone Analogs 50. Monitoring of Ovarian Stimulation 51. Ovulation Trigger 52. Individualized Controlled Ovarian Stimulation 53. In Vitro Fertilization Lite 54. Role of Luteinizing Hormone in Ovarian Stimulation 55. Anesthesia in Assisted Reproductive Techniques 56. Oocyte Retrieval. 57. Embryo Transfer 58. Troubleshooting in Assisted Reproductive Technology 59. Luteal Phase Support SECTION 8: DILEMMA IN ART 60. Poor Responder 61. Recurrent Implantation Failure 62. Empty Follicle Syndrome 63. Role of Aneuploidy Screening in Preimplantation Embryos 64. Preimplantation Genetic Testing of Embryos 65. Epigenetics and Assisted Reproductive Technology SECTION 9: COMPLICATIONS IN ART 66. Ovarian Hyperstimulation Syndrome 67. Ectopic Pregnancy 68. Multipleorder Births SECTION 10: THIRD PARTY REPRODUCTION 69. Oocyte and Sperm Donation 70. Surrogacy in Assisted Reproductive Technology 71. Assisted Reproductive Technology Guidelines 72. Adoption 73. LGBTQ and Fertility 74. Transgender Population and Fertility SECTION 11: OUTCOME FOLLOWING ASSISTED REPRODUCTIVE TECHNIQUE 75. Maternal and Fetal Outcomes Following Assisted Reproductive Technique 76. Early Pregnancy Scan 77. Recurrent Pregnancy Loss: From Diagnostic Dilemmas to Clinical Decisions SECTION 12: RECENT ADVANCES 78. Bioengineered Human Endometrium In Vitro. 79. Recent Trends in A...
Offers a comprehensive guide to assisted reproductive technology surveillance, describing its history, global variations, and best practices.
This comprehensive review of the factors that affect the harvesting and preparation of oocytes and the management of embryos will allow practitioners to make evidence-based decisions for successful IVF. The book reviews and re-considers the value of strategies and outcomes in the management of fertility and conception rates, centred on the production of oocytes, and successful development of the embryo. Authored by leading experts in the field, chapters engage with treatments and strategies that affect the production of oocytes and embryos, optimizing outcomes in the management of female fertility, conception rates, and live births. This vital guide covers controlled ovarian hyperstimulation, the role of AMH in determining ovarian reserve, and primary stimulation agents and the use of adjuncts. Integral for all clinicians and embryologists working in reproductive medicine units, readers are provided with evidence-based, comprehensive advice and review of all factors affecting the management of oocytes and the embryo that are vital for successful IVF cycles.
Ovarian Stimulation Protocols is a concise handbook that aims to deliver everything the reader needs to know for performing a risk-free ovarian stimulation for assisted reproductive technique (ART) and get a favorable outcome. Review of crucial issues such as the significance of monitoring ovarian stimulation, advantages and disadvantages of ovarian hyperstimulation versus minimal stimulation, and the use of various drug regimens and stimulation protocols for various patient sub-sets, will help clinicians in selecting the better or more appropriate protocols. The contributors of this book have leading scientific and clinical backgrounds, with years of experience to support their views. The book serves as a handy practical guide, targeting and settling clinical dilemma that ART practitioners commonly experience in their clinics, while providing a window to the newer developments. ​
Human Assisted Reproductive Technology: Future Trends in Laboratory and Clinical Practice offers a collection of concise, practical review articles on cutting-edge topics within reproductive medicine. Each article presents a balanced view of clinically relevant information and looks ahead to how practice will change over the next five years. The clinical section discusses advances in reproductive surgery and current use of robotic surgery for tubal reversal and removal of fibroids. It looks into the refinement of surgical procedures for fertility preservation purposes. Chapters also discuss non-invasive diagnosis of endometriosis with proteomics technology, new concepts in ovarian stimulation and in the management of polycystic ovary syndrome, and evidence-based ART. The embryology section discusses issues ranging from three-dimensional in-vitro ovarian follicle culture, and morphometric and proteomics analysis of embryos, to oocyte and embryo cyropreservation. This forward-looking volume of review articles is key reading for reproductive medicine physicians, gynecologists, reproductive endocrinologists, urologists and andrologists.
The different chapters in the book cover a wide range of reproductive medicine and science. They represent the cutting-edges of each discipline and are written by acknowledged experts in the field. The editors have endeavored to select contributors who are at the forefront of their disciplines, thereby ensuring the freshness of each chapter. This book is divided into seven sections: Infertility management, ART, embryology, endoscopy, male factor, USG in infertility and advances in infertility management. The book was written with the aim of providing current and practical approaches for patient management.
The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook – inspired by the postgraduate degree program at the University of Oxford – guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology.
This comprehensive and authoritative book is written by over seventy of the foremost experts working with the care of transgender and gender expansive patients for gynecologists and those working in neighboring disciplines. Among medical specialists, understanding of the complex reality and medical needs of transgender and gender diverse individuals is still limited. This book offers the opportunity to understand transgynecology in a way that is inclusive and up-to-date, with insights into liaison with specialties such as urology, dermatology, sexuology, physiotherapy amongst others. By contextualising transgender/gender diverse medicine before covering specific issues such as imaging, benign disorders, fertility maintenance, medico-legal concerns and uterine transplantation, this book is truly unique. Aimed at gynecologists, obstetricians, general practitioners, counsellors and all those who work with transgender, non-binary, or gender diverse patients, this book prepares the reader for the prerequisites and subtleties of transgynecology.