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Oocyte cryopreservation entails important potential advantages for humanIVF, offering a less ethically disputable alternative to embryo cryopreservation,simplifying and making safer oocyte donation, and giving an opportunity forfertility preservation to women at risk of premature ovarian failure as an effectof genetic factors or chemo- or radiother
The specialty of fertility preservation offers patients with cancer, who are rendered infertile by chemo- and radiotherapy, the opportunity to realize their reproductive potential. This gold-standard publication defines the specialty. The full range of techniques and scientific concepts is covered in detail, and the author team includes many of the world's leading experts in the field. The book opens with introductions to fertility preservation in both cancer and non-cancer patients, followed by cancer biology, epidemiology and treatment, and reproductive biology and cryobiology. Subsequent sections cover fertility preservation strategies in males and females, including medical/surgical procedures, ART, cryopreservation and transplantation of both ovarian tissue and the whole ovary, and in-vitro follicle growth and maturation. Concluding chapters address future technologies, as well as ethical, legal and religious issues. Richly illustrated throughout, this is a key resource for all clinicians specializing in reproductive medicine, gynecology, oncology, hematology, endocrinology and infertility.
Welcomed as liberation and dismissed as exploitation, egg freezing (oocyte cryopreservation) has rapidly become one of the most widely-discussed and influential new reproductive technologies of this century. In Freezing Fertility, Lucy van de Wiel takes us inside the world of fertility preservation—with its egg freezing parties, contested age limits, proactive anticipations and equity investments—and shows how the popularization of egg freezing has profound consequences for the way in which female fertility and reproductive aging are understood, commercialized and politicized. Beyond an individual reproductive choice for people who may want to have children later in life, Freezing Fertility explores how the rise of egg freezing also reveals broader cultural, political and economic negotiations about reproductive politics, gender inequities, age normativities and the financialization of healthcare. Van de Wiel investigates these issues by analyzing a wide range of sources—varying from sparkly online platforms to heart-breaking court cases and intimate autobiographical accounts—that are emblematic of each stage of the egg freezing procedure. By following the egg’s journey, Freezing Fertility examines how contemporary egg freezing practices both reflect broader social, regulatory and economic power asymmetries and repoliticize fertility and aging in ways that affect the public at large. In doing so, the book explores how the possibility of egg freezing shifts our relation to the beginning and end of life.
This volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking to optimize their successful use of these components.
An indispensable practical tool for embryologists and reproductive medicine specialists seeking to offer their patients this revolutionary treatment option.
The new edition of this text admirably fills the need for a primer on the central topics involved in Human In Vitro Fertilization (IVF). Supplying a comprehensive and hands-on approach to IVF, this source presents established state-of-the-art procedures and techniques, as well as the most current research in the field. Expert contributors also discuss the history of IVF and the potential of future research. Offering essential information for reproductive endocrinologists, IVF practitioners and embryologists, this book guides readers though every step of human assisted conception, from patient pre-treatment to monitoring of outcomes.
Vitrification in Assisted Reproduction presents standard and new cryopreservation techniques in detail, outlining those that have resulted in success, and providing recommended means for overcoming typically encountered problems.This new edition provides a much broader range of clinical application and data to demonstrate its contribution to the us
Practical and effective; this book supports challenging clinical and laboratory issues that the IVF practitioner faces all day, every day.
This practical book focuses on the most recent advances in fertility preservation in oncological and non-oncological patients. It presents the steps that need to be followed prior to treatment for successful fertility preservation, and describes in detail the medical conditions requiring fertility preservation, including precise information on the risk of fertility loss, prognosis, risk of ovarian metastasis and other possible risks. The book also provides information on how to perform the preservation techniques (success rates, risks, etc.) and on what to do after the treatment (in cases of bleeding during chemotherapy, menopause, wish to conceive, etc.). Written by experts in the field, including members of the globally known network FertiPROTEKT and leading oncologists and specialists, this practical and easy-to-use book is a valuable resource for all clinicians involved in fertility preservation for patients with specific diseases