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The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.
Describes the analysis and conclusions of the National Institute of Environmental Health Sciences (NIEHS) regarding possible health effects from ELF-EMF (magnetic field) exposures. The NIEHS carried out a hazard evaluation of ELF-EMF exposure that examined both historical and novel scientific evidence on possible health and biological effects at a series of open, scientific meetings. The scientific evidence suggesting that ELF-EMF exposures pose any health risk is weak, and there is a lack of connection between the human data and the experimental data (animal and mechanistic).
Can the electric and magnetic fields (EMF) to which people are routinely exposed cause health effects? This volume assesses the data and draws conclusions about the consequences of human exposure to EMF. The committee examines what is known about three kinds of health effects associated with EMF: cancer, primarily childhood leukemia; reproduction and development; and neurobiological effects. This book provides a detailed discussion of hazard identification, dose-response assessment, exposure assessment, and risk characterization for each. Possible Health Effects of Exposure to Residential Electric and Magnetic Fields also discusses the tools available to measure exposure, common types of exposures, and what is known about the effects of exposure. The committee looks at correlations between EMF exposure and carcinogenesis, mutagenesis, neurobehavioral effects, reproductive and developmental effects, effects on melatonin and other neurochemicals, and effects on bone healing and stimulated cell growth.
The idea of free (or laissez-faire) banking has enjoyed a remarkable renaissance in recent years. It is a radical idea that challenges much of what many monetary and banking scholars still take for granted - that banking is inherently unstable, that the banking system needs a lender of last resort or deposit insurance to defend it in a crisis, and that the government has to protect the value of the currency. Against this free banking sets an argument which is in essence very simple: if markets are generally better at allocating resources than governments, then what is different about money and the industry that provides it and why should they be treated differently?
The overall purpose of this study is to investigate the role that environmental-level magnetic fields may play as an exogenous factor in the etiology of human breast cancer. There are several important observations that have been made during the research conducted in this reporting period. We have further characterized the EMF blocking effect on the oncostatic action of melatonin and tamoxifen on human breast cancer cell growth in vitro. Field dose studies suggest that this blocking effect is observed at field strengths of up to 1Gauss (1000mG, 100uTesla) with a lower threshold between 6 - 12mG. Studies investigating the critical duration of exposure suggest that at least two days of continuous field exposure is required; this corresponds to one cell-cycle period. In biologically-based studies it was shown that melatonin concentration in the media itself is not influenced by a 2 vs 12mG magnetic field. The original melatonin findings presented in our proposal recently have been independently replicated at the EPA.