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In 2001, first reports of the human draft genome were published. Since then, genomes of many other organisms have been sequenced, including several primate species: the chimpanzee, rhesus macaque, gorilla, orangutan, gibbon, baboon, marmoset, tarsier, galago, lemur, and more recently Neanderthals. In a new era of "post-genome biology", scientists now have the vast amount of information revealed by genome research to confront one of the most challenging, fundamental questions in primatology and anthropology: What makes us human? This volume comprises a collection of articles on a variety of topics relevant to primate genomes, including evolution, human origins, genome structure, chromosome genomics, and bioinformatics. The book covers the cutting-edge research in molecular primatology and provides great insights into the functional diversity of primates. This valuable collection will benefit researchers and students, including primatologists, anthropologists, molecular biologists, evolutionary biologists, and animal behaviorists.
In 2001, scientists were finally able to determine the full human genome sequence, and with the discovery began a genomic voyage back in time. Since then, we have sequenced the full genomes of a number of mankind's primate relatives at a remarkable rate. The genomes of the common chimpanzee (2005) and bonobo (2012), orangutan (2011), gorilla (2012), and macaque monkey (2007) have already been identified, and the determination of other primate genomes is well underway. Researchers are beginning to unravel our full genomic history, comparing it with closely related species to answer age-old questions about how and when we evolved. For the first time, we are finding our own ancestors in our genome and are thereby gleaning new information about our evolutionary past. In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their source among our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer. For example, what does the high level of discordance among the gene trees of humans and the African great apes tell us about our respective separations from our common ancestor? Was our separation from the apes fast or slow, and when and why did it occur? Where, when, and how did our modern species evolve? How do we search across genomes to find the genomic underpinnings of our large and complex brains and language abilities? How can we find the genomic bases for life at high altitudes, for lactose tolerance, resistance to disease, and for our different skin pigmentations? How and when did we interbreed with Neandertals and the recently discovered ancient Denisovans of Asia? Harris draws upon extensive experience researching primate evolution in order to deliver a lively and thorough history of human evolution. Ancestors in Our Genome is the most complete discussion of our current understanding of the human genome available.
Genomic science indicates that humans descend not from an individual pair but from a large population. What does this mean for the basic claim of many Christians: that humans descend from Adam and Eve? Leading evangelical geneticist Dennis Venema and popular New Testament scholar Scot McKnight combine their expertise to offer informed guidance and answers to questions pertaining to evolution, genomic science, and the historical Adam. Some of the questions they explore include: - Is there credible evidence for evolution? - Do we descend from a population or are we the offspring of Adam and Eve? - Does taking the Bible seriously mean rejecting recent genomic science? - How do Genesis's creation stories reflect their ancient Near Eastern context, and how did Judaism understand the Adam and Eve of Genesis? - Doesn't Paul's use of Adam in the New Testament prove that Adam was a historical individual? The authors address up-to-date genomics data with expert commentary from both genetic and theological perspectives, showing that genome research and Scripture are not irreconcilable. Foreword by Tremper Longman III and afterword by Daniel Harrell.
Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million individuals. This volume brings some of the world's best investigators to describe recent advances in both the scientific and clinical aspects of malaria, and bridges between the two.
This book introduces to the reader unfamiliar with primatology in Japan three research projects representative of the unique multidisciplinary approach carried out by scientists at Kyoto University, the country’s premier institution for primate studies. The projects are all aimed at understanding the age-old questions, where did we come from, and what makes us unique or similar to our primate ancestors? The first chapter, by Naofumi Nakagawa, focuses on the cultural diversity of social behavior in the Japanese macaque. This chapter reviews research on primate culture, in particular the work on Japanese macaques, then presents what is arguably the first example of a culturally transmitted social convention in the species, called “hug-hug”. The second chapter, by Michael A. Huffman, introduces our current knowledge of self-medication in primates, based largely on a long-term study of wild chimpanzees at Kyoto University’s longest ongoing chimpanzee field in Africa, Mahale, in Tanzania. The suite of behavioral adaptations to parasite infections in chimpanzees is compared with our current knowledge of self-medication in other primates and other animal species. The third chapter, by Yasuhiro Go, Hiroo Imai, and Masaki Tomonaga, describes the ambitious efforts to combine cognitive science and genomics into a new discipline called “comparative cognitive genomics”. This chapter provides an overview of recent advancements in chimpanzee comparative cognition, the construction of a chimpanzee genomic database, and comparative genomic studies at the individual level, looking into factors affecting personality and individuality.
This book presents 19 selected contributions to the 20th Evolutionary Biology Meeting in Marseille, which took place in September 2016. They are grouped under the following major themes: · Self/Nonself Evolution · Species Evolution and Evolution of Complex Traits · Methods and Concepts The aims of the annual meetings in Marseille – which bring together leading evolutionary biologists and other scientists using evolutionary biology concepts, e.g. for medical research – are to promote the exchange of ideas and to encourage interdisciplinary collaborations. Offering a revealing overview of the latest findings in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students alike.
Presents a comprehensive review of nonhuman primate audition and vocal communication. These are obviously intimately related topics, but are often addressed separately. The hearing abilities of primates have been tested experimentally in a large number of species across the primate order, and these studies have revealed both consistent patterns as well as interesting variation within and between taxonomic groups. Recent studies have shed light on how variation in anatomical structures along the auditory pathway relates to variation in auditory sensitivity. At the same time, ongoing studies of vocal communication in wild primate populations continue to reveal new insights into the social and environmental contexts of many primate calls, and the range of known primate vocalizations has increased dramatically with the development of more sophisticated and accessible auditory equipment and software that enables the recording and analysis of higher-fidelity and broader-band recordings, including documenting very high frequency (i.e. ultrasound) vocalizations. Historically the relative importance of primate calls has been evaluated qualitatively by the perception of the researcher, but new methods and approaches now enable a greater appreciation for how signals are used and perceived by the primates in question. The integration of anatomical and behavioral data on acoustic communication and the environmental correlates thereof has significant potential for reconstructing behavior in the fossil record. This confluence of factors and accumulating evidence for the sophistication and complexity in both the signal and its interpretation indicate that a book synthesizing this information across primates is warranted and represents an important contribution to the literature.
Exploring everything from nutrients to food acquisition and research methods, a comprehensive synthesis of the study of diet and feeding in nonhuman primates. What do we mean when we say that a diet is nutritious? Why can some animals get all the energy they need from eating leaves while others would perish on such a diet? Why don’t mountain gorillas eat fruit all day as chimpanzees do? Answers to these questions about food and feeding are among the many tasty morsels that emerge from this authoritative book. Informed by the latest scientific tools and millions of hours of field and laboratory work on species across the primate order and around the globe, this volume is an exhaustive synthesis of our understanding of what, why, and how primates eat. State-of-the-art information presented at physiological, behavioral, ecological, and evolutionary scales will serve as a road map for graduate students, researchers, and practitioners as they work toward a holistic understanding of life as a primate and the urgent conservation consequences of diet and food availability in a changing world.
This book tells the dramatic story of Crispr and the potential impact of this gene-editing technology.
Our understanding of human color vision has advanced tremendously in recent years, helped along by many new discoveries, ideas, and achievements. It is therefore timely that these new developments are brought together in a book, assembled specifically to include new research and insight from the leaders in the field. Although intentionally not exhaustive, many aspects of color vision are discussed in this Springer Series in Vision Research book including: the genetics of the photopigments; the anatomy and physiology of photoreceptors, retinal and cortical pathways; color perception; the effects of disorders; theories on neuronal processes and the evolution of human color vision. Several of the chapters describe new, state-of-the-art methods within genetics, morphology, imaging techniques, electrophysiology, psychophysics, and computational neuroscience. The book gives a comprehensive overview of the different disciplines in human color vision in a way that makes it accessible to specialists and non-specialist scientists alike. About the Series: The Springer Series in Vision Research is a comprehensive update and overview of cutting edge vision research, exploring, in depth, current breakthroughs at a conceptual level. It details the whole visual system, from molecular processes to anatomy, physiology and behavior and covers both invertebrate and vertebrate organisms from terrestrial and aquatic habitats. Each book in the Series is aimed at all individuals with interests in vision including advanced graduate students, post-doctoral researchers, established vision scientists and clinical investigators. The series editors are N. Justin Marshall, Queensland Brain Institute, The University of Queensland, Australia and Shaun P. Collin, Neuroecology Group within the School of Animal Biology and the Oceans Institute at the University of Western Australia.