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Explores the most personal, mirthful, disturbing and cherished times of our lives in essay form.
Understanding risk -- Putting risk in perspective -- Risk charts : a way to get perspective -- Judging the benefit of a health intervention -- Not all benefits are equal : understand the outcome -- Consider the downsides -- Do the benefits outweight the downsides? -- Beware of exaggerated importance -- Beware of exaggerated certainty -- Who's behind the numbers?
In 1900, for every 1,000 babies born in the United States, 100 would die before their first birthday, often due to infectious diseases. Today, vaccines exist for many viral and bacterial diseases. The National Childhood Vaccine Injury Act, passed in 1986, was intended to bolster vaccine research and development through the federal coordination of vaccine initiatives and to provide relief to vaccine manufacturers facing financial burdens. The legislation also intended to address concerns about the safety of vaccines by instituting a compensation program, setting up a passive surveillance system for vaccine adverse events, and by providing information to consumers. A key component of the legislation required the U.S. Department of Health and Human Services to collaborate with the Institute of Medicine to assess concerns about the safety of vaccines and potential adverse events, especially in children. Adverse Effects of Vaccines reviews the epidemiological, clinical, and biological evidence regarding adverse health events associated with specific vaccines covered by the National Vaccine Injury Compensation Program (VICP), including the varicella zoster vaccine, influenza vaccines, the hepatitis B vaccine, and the human papillomavirus vaccine, among others. For each possible adverse event, the report reviews peer-reviewed primary studies, summarizes their findings, and evaluates the epidemiological, clinical, and biological evidence. It finds that while no vaccine is 100 percent safe, very few adverse events are shown to be caused by vaccines. In addition, the evidence shows that vaccines do not cause several conditions. For example, the MMR vaccine is not associated with autism or childhood diabetes. Also, the DTaP vaccine is not associated with diabetes and the influenza vaccine given as a shot does not exacerbate asthma. Adverse Effects of Vaccines will be of special interest to the National Vaccine Program Office, the VICP, the Centers for Disease Control and Prevention, vaccine safety researchers and manufacturers, parents, caregivers, and health professionals in the private and public sectors.
"This book has been divided into three main sections. Part I deals with global issues that bear on the assessment and formulation of possible adverse effects and with pertinent concepts related to basic pharmacology, physiology, and medical monitoring. The chapters in Part II present information organized by individual organ systems or specific medical circumstances rather than by drugs or drug classes. This approach seems to provide a logical and comprehensible format that allow readers to search out information as referenced by a particular side effect (and its varied potential causes) and to locate a discussion of practical management strategies. Part III focuses on summary recommendations covering all the material presented in the book and is followed by helpful appendixes on self-assessment questions and resources for practitioners. The book is meant to serve as a ready reference that simultaneously provides scientific and scholarly discussion of available treatment options and presents their scientific rationales."--page xx.
An invaluable guide to psychiatric presentation, diagnosis and treatment in a primary care setting.
An unforgettable memoir about the turmoil of antidepressant withdrawal and the work it takes to unravel the stories we tell ourselves to rationalize our suffering. Brooke Siem was among the first generation of minors to be prescribed antidepressants. Initially diagnosed and treated in the wake of her father’s sudden death, this psychiatric intervention sent a message that something was pathologically wrong with her and that the only “fix” was medication. As a teenager, she stepped into the hazy world of antidepressants just at the time when she was forming the foundation of her identity. For the following fifteen years, every situation she faced was seen through the lens of brokenness. A decade and a half later, still on the same cocktail of drugs, Brooke found herself hanging halfway out her Manhattan high-rise window, calculating the time it would take to hit the ground. As she looked for breaks in the pedestrian traffic patterns, a thought dawned on her: “I’ve spent half my life—and my entire adult life—on antidepressants. Who might I be without them?” Unfurled against a global backdrop, May Cause Side Effects is the gripping story of what happened when, after fifteen years and 32,760 pills, Brooke was faced with a profound choice that plunged her into a year of excruciating antidepressant withdrawal and forced her to rebuild her entire life. An illuminating memoir for those who take, prescribe, or are considering psychiatric drugs, May Cause Side Effects is an honest reminder that the road to true happiness is not mapped on a prescription pad. Instead, Brooke’s story reveals the messy reality of how healing begins at the bottomless depth of our suffering, in the deep self-work that pushes us to the edges of who we are.
This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. And this Expert Consult Edition offers online access to the complete contents of the 2-volume set, fully searchable, and much more. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge.
Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.
Ordinary citizens face a frustrating and increasingly complex maze of human service agencies when they seek help for everyday problems, even though one stop information and referral centers have been established to facilitate information seeking in many communities. This book explores the relationship between the information needs of battered women and the information response provided through social networks in six communities of varying size. The book is based on an award-winning study, in which 543 women described their knowledge of the problem of woman abuse and what kinds of information resources would be helpful to an abused woman. In the second phase of the study, 179 interviews were conducted with service providers identified by these women as likely sources of help. A comparison of the interviews demonstrates that the response of information delivery systems does not adequately meet the needs and expectations of those women who would seek such services. The final chapters of the volume focus on the implications of this study for the design of social service systems.