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Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering.The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility.Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. - Examines the sources, processing and properties of natural based polymers for biomedical applications - Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality - Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine
Research on applications of polymers for biomedical applications has increased dramatically to find improved medical plastics for this rapidly evolving field. This book brings together various aspects of recent research and developments within academia and industry related to polymers for biomedical applications.
Polymers have generated considerable interest in a large number of technologically important fields such as human healthcare systems. Polymers represent a very important domain of materials and have become an integral part of day to day human life. Polymers exist in nature; they have been and continue to be an integral part of the universe. This book is intended for scientists and researchers to use in their research or in their professional practice in polymer chemistry and its biomedical applications. Multiple biological, synthetic and hybrid polymers are used for multiple medical applications. A wide range of different polymers are available, and they have the advantage to be tunable in physical, chemical and biological properties and in a wide range to match the requirements of specific applications. This book gives a brief overview about the introduction and developments of polymers for different applications. The biomedical polymers comprise not only bulk materials, but also coatings and pharmaceutical nano-carriers for drugs. The surface modification of the inorganic nanoparticles with a physically or chemically end-tethered polymer chain has been employed to overcome the problems associated with the polymers. Chemically attached polymer chains not only stabilize the inorganic nanoparticles, but also lead to photosensitivity, bioactivity, biocompatibility and pharmacological properties in the composites. Polymer encapsulated silica nanocomposites (mesoporous) have potential applications in different fields, such as optics, bio-catalysis, microelectronics bone tissue engineering, coatings cosmetics, inks, agriculture, drug release systems, diagnoses, enzyme imaging, temperature-responsive materials, and thermosensitive vehicles for cellular imaging. Polymer grafted nanosized particles are known to have excellent properties such as good dispersion ability in solvents and polymer matrices. Polymer-based controlled drug delivery systems have some specific advantages, such as improved efficiency and reduced toxicity. The incorporation of a thermoresponsive polymer layer often enhances protein absorption and specific biomolecular tagging through hydrogen bonding. As a result, the nanocomposite gets cleared from the body at a faster rate (blood residence becomes low). This book is composed of fourteen edited chapters; it is intended for scientists and researchers to use in their research or in their professional practice in polymer chemistry and its biomedical applications.
Bioresorbable Polymers for Biomedical Applications: From Fundamentals to Translational Medicine provides readers with an overview of bioresorbable polymeric materials in the biomedical field. A useful resource for materials scientists in industry and academia, offering information on the fundamentals and considerations, synthesis and processing, and the clinical and R and D applications of bioresorbable polymers for biomedical applications. - Focuses on biomedical applications of bioresorbable polymers - Features a comprehensive range of topics including fundamentals, synthesis, processing, and applications - Provides balanced coverage of the field with contributions from academia and industry - Includes clinical and R and D applications of bioresorbable polymers for biomedical applications
Polymers are important and attractive biomaterials for researchers and clinical applications due to the ease of tailoring their chemical, physical and biological properties for target devices. Due to this versatility they are rapidly replacing other classes of biomaterials such as ceramics or metals. As a result, the demand for biomedical polymers has grown exponentially and supports a diverse and highly monetized research community. Currently worth $1.2bn in 2009 (up from $650m in 2000), biomedical polymers are expected to achieve a CAGR of 9.8% until 2015, supporting a current research community of approximately 28,000+. Summarizing the main advances in biopolymer development of the last decades, this work systematically covers both the physical science and biomedical engineering of the multidisciplinary field. Coverage extends across synthesis, characterization, design consideration and biomedical applications. The work supports scientists researching the formulation of novel polymers with desirable physical, chemical, biological, biomechanical and degradation properties for specific targeted biomedical applications. - Combines chemistry, biology and engineering for expert and appropriate integration of design and engineering of polymeric biomaterials - Physical, chemical, biological, biomechanical and degradation properties alongside currently deployed clinical applications of specific biomaterials aids use as single source reference on field. - 15+ case studies provides in-depth analysis of currently used polymeric biomaterials, aiding design considerations for the future
With its content taken from only the very latest results, this is an extensive summary of the various polymeric materials used for biomedical applications. Following an introduction listing various functional polymers, including conductive, biocompatible and conjugated polymers, the book goes on to discuss different synthetic polymers that can be used, for example, as hydrogels, biochemical sensors, functional surfaces, and natural degradable materials. Throughout, the focus is on applications, with worked examples for training purposes as well as case studies included. The whole is rounded off with a look at future trends.
Smart polymers for biomedical applications are presently one focuses in biomedical materials research. Smart polymers are becoming increasingly more prevalent as scientists learn about the chemistry and triggers that induce conformational changes in polymer structures and devise ways to take advantage of, and control them. New polymeric materials are being chemically formulated that sense specific environmental changes in biological systems, and adjust in a predictable manner, making them useful tools for drug delivery, tissue engineering, biosensor design, wound healing and other metabolic control mechanisms. In this relatively new area of biotechnology, many advances are made in the recent years, but no latest books or edited collections have well summarised the recent advances. This book is the only book that has latest research developments on smart-polymeric materials for biomedical applications which include drug delivery, tissue engineering, biosensors, wound healing and many other allied fields.
Advanced Functional Polymers for Biomedical Applications presents novel techniques for the preparation and characterization of functionalized polymers, enabling researchers, scientists and engineers to understand and utilize their enhanced functionality in a range of cutting-edge biomedical applications. - Provides systematic coverage of the major types of functional polymers, discussing their properties, preparation techniques and potential applications - Presents new synthetic approaches alongside the very latest polymer processing and characterization methods - Unlocks the potential of functional polymers to support ground-breaking techniques for drug and gene delivery, diagnostics, tissue engineering and regenerative medicine
Materials for Biomedical Engineering: Thermoset and Thermoplastic Polymers presents the newest and most interesting approaches to intelligent polymer engineering in both current and future progress in biomedical sciences. Particular emphasis is placed on the properties needed for each selected polymer and how to increase their biomedical potential in varying applications, such as drug delivery and tissue engineering. These materials are intended for use in diagnoses, therapy and prophylaxis, but are also relatable to other biomedical related applications, such as sensors. Recent developments and future perspectives regarding their use in biomedicine are discussed in detail, making this book an ideal source on the topic. - Highlights the most well-known applications of thermoset and thermoplastic polymers in biological and biomedical engineering - Presents novel opportunities and ideas for developing or improving technologies in materials for companies, those in biomedical industries, and others - Features at least 50% of references from the last 2-3 years
Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment. - Summarizes the most recent strategies to develop nanostructured polymer composite biomaterials for biomedicine - Outlines the major preparation and characterization techniques for a range of polymer nanocomposites used in biomedicine - Explores the design of new types of nanostructured polymer composites for applications in drug delivery, tissue engineering, gene therapy and bone replacement