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This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.
This volume is the proceedings from the Swiss Society for Neuropathology XVIIIth International Winter Meeting, held March 23-26, 2000, in St. Moritz, Switzerland. For more than 35 years the Swiss Society of Neuropathology has organised its traditional International Winter Meeting, whose main aim is to bring together neuropathologists and clinicians as well as neuroscientists interested in disease mechanisms. The topic of the 2000 Meeting was Neuropathology and Genetics of Dementia. A programme of invited plenary lectures of high educational value as well as platform and poster presentations given by many participants covered the broad spectrum of dementing disorders. Encouraged by the high standard of the meeting, and probably also influenced by the advent of a new Millennium, it was decided to publish the Proceedings of the 2000 Meeting in the present book.
With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.
This book looks at the role of proteases, which are enzymes that digest proteins, and the various roles that proteases play in the development of neurodegenerative diseases such as Alzheimer's disease, ALS, epilepsy, multiple sclerosis, as well as numerous other neuromuscular diseases.
This book on the local and systemic manifestations and correlates of temporomandibular joint disorders (TMDs) encompasses the two intertwined facets of translational science – translational research and translational effectiveness – as they relate specifically to TMDs. The first part of the book, on recent translational research, focuses on topics such as the neuroanatomy and neurophysiology of the trigeminal nerve and trigeminal network system, the manifestations of neuroinflammation in TMDs, and the molecular mechanisms underlying TMDs. The second part discusses the clinical effectiveness of treatment approaches from the perspective of evidence-based dentistry, with careful attention to the critical relationships between dental malocclusions, the signs and symptoms of TMDs, and airway/breathing disorders. Interventions to correct for malocclusal conditions that lead to TMDs are examined, with explanation of the ways in which they can ameliorate a variety of local and systemic symptoms. This will be an excellent reference book for established practitioners, residents, interns, and students as well as a powerful cutting-edge document for researchers in the field.
Presents a modern vision of anaesthesia, integrating technology and knowledge, to change how anaesthesia is taught and practised.
This guide to damage control surgery focuses on the decision-making process for managing polytrauma. Orthopedists, trauma surgeons, and emergency medicine physicians will learn how to effectively coordinate efforts. The book presents an overview of the damage control concept and the epidemiology of polytrauma injuries. Immunological changes, cascade reactions, and patient selection are discussed. Indications for life-saving procedures, damage control for truncal injuries, and damage control for extremities and pelvic fractures are outlined as well. The text also covers vascular injuries and secondary definitive procedures.
This book offers a broad-ranging assessment of current efforts of the molecular, cellular, hormonal, nutritional and lifestyle strategies being tested and applied by biogerontologists in the search for effective means of intervention, prevention and treatment of age-related diseases, and for achieving healthy old age. Employing a semi-academic style, the book presents data from experimental systems, while focusing primarily on their applications to humans in the prevention and treatment of age-related impairments.
1h The 5 International Conference on the Progress in Alzheimer's Disease and Parkinson's 51 1 Disease took place from March 31 to April 5 \ 2001 in Kroto, Japan. This international 1 conference was organized as a joint Congress with the 9 International Catecholamine Symposium. A total of 1258 clinicians and researchers participated in this joint congress 1h from 38 countries in the world. This book represents the proceedings of the 5 Conference on Alzheimer's and Parkinson's disease. The International Conference on the Progress in Alzheimer's and Parkinson's disease was first launched by Professor Abraham Fisher of Israel and Professor Israel Hanin of USA. The first conference was held in Eilat, Israel in 1985. The second conference was organized in Kyoto, Japan in 1989; the third one in Chicago, USA, in 1993, and the fourth one in Eilat, Israel in 1997. The International Catecholamine Symposium (ICS) is an international meeting devoted to the development of basic as well as clinical research on catecholamines. The first Catecholamine Symposium was held in Bethesda, USA in 1958. Since then this symposium has occurred every 5 years. Professor Toshiharu Nagatsu was appointed as 1h the president of the 9 International Catecholamine Symposium, which was to be held in 200 I also in Japan. Therefore, we decided to organize a joint congress of the two meetings, because there is much overlap in research between Alzheimer's disease, Parkinson's disease, and catecholamines. We thank Professor Nagatsu very much for agreeing to organizing this joint congress.