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A Guided Study (Masterworks of Discovery)
The Foundations of Genetics describes the historical development of genetics with emphasis on the contributions to advancing genetical knowledge and the various applications of genetics. The book reviews the work of Gregor Mendel, his Law of Segregation, and of Ernst Haeckel who suggested that the nucleus is that part of the cell that is responsible for heredity. The text also describes the studies of W. Johannsen on "pure lines," and his introduction of the terms gene, genotype, and phenotype. The book explains the theory of the gene and the notion that hereditary particles are borne by the chromosomes (Sutton-Boveri hypothesis). Of the constituent parts of the nucleus only the chromatin material divides at mitosis and segregates during maturation. Following studies confirm that the chromatin material, present in the form of chromosomes with a constant and characteristic number and appearance for each species, is indeed the hereditary material. The book describes how Muller in 1927, showed that high precision energy radiation is the external cause to mutation in the gene itself if one allele can mutate without affecting its partner. The superstructure of genetics built upon the foundations of Mendelism has many applications including cytogenetics, polyploidy, human genetics, eugenics, plant breeding, radiation genetics, and the evolution theory. The book can be useful to academicians and investigators in the fields of genetics such as biochemical, biometrical, microbial, and pharmacogenetics. Students in agriculture, anthropology, botany, medicine, sociology, veterinary medicine, and zoology should add this text to their list of primary reading materials.
"Noel Kingsbury reveals that even those imaginary perfect foods are themselves far from anything that could properly be called natural, rather, they represent the end of a millennia-long history of selective breeding and hybridization. Starting his story at the birth of agriculture, Kingsbury traces the history of human attempts to make plants more reliable, productive, and nutritiousa story that owes as much to accident and error as to innovation and experiment. Drawing on historical and scientific accounts, as well as a rich trove of anecdotes, Kingsbury shows how scientists, amateur breeders, and countless anonymous farmers and gardeners slowly caused the evolutionary pressures of nature to be supplanted by those of human needs and thus led us from sparse wild grasses to succulent corn cobs, and from mealy, white wild carrots to the juicy vegetables we enjoy today. At the same time, Kingsbury reminds us that contemporary controversies over the Green Revolution and genetically modified crops are not new, plant breeding has always had a political dimension."--Publisher's description.
Bateson named the science "genetics" in 1905-1906. This is the first textbook in English on the subject of genetics.
"Endless forms most beautiful and most wonderful have been, and are being, evolved," Darwin famously concluded The Origin of Species, and for confirmation we look to...the guinea pig? How this curious creature and others as humble (and as fast-breeding) have helped unlock the mystery of inheritance is the unlikely story Jim Endersby tells in this book. Biology today promises everything from better foods or cures for common diseases to the alarming prospect of redesigning life itself. Looking at the organisms that have made all this possible gives us a new way of understanding how we got here--and perhaps of thinking about where we're going. Instead of a history of which great scientists had which great ideas, this story of passionflowers and hawkweeds, of zebra fish and viruses, offers a bird's (or rodent's) eye view of the work that makes science possible. Mixing the celebrities of genetics, like the fruit fly, with forgotten players such as the evening primrose, the book follows the unfolding history of biological inheritance from Aristotle's search for the "universal, absolute truth of fishiness" to the apparently absurd speculations of eighteenth-century natural philosophers to the spectacular findings of our day--which may prove to be the absurdities of tomorrow. The result is a quirky, enlightening, and thoroughly engaging perspective on the history of heredity and genetics, tracing the slow, uncertain path--complete with entertaining diversions and dead ends--that led us from the ancient world's understanding of inheritance to modern genetics.
Racism in America has been the subject of serious scholarship for decades. At Harvard University Press, we’ve had the honor of publishing some of the most influential books on the subject. The excerpts in this volume—culled from works of history, law, sociology, medicine, economics, critical theory, philosophy, art, and literature—are an invitation to understand anti-Black racism through the eyes of our most incisive commentators. Readers will find such classic selections as Toni Morrison’s description of the Africanist presence in the White American literary imagination, Walter Johnson’s depiction of the nation’s largest slave market, and Stuart Hall’s theorization of the relationship between race and nationhood. More recent voices include Khalil Gibran Muhammad on the pernicious myth of Black criminality, Elizabeth Hinton on the link between mass incarceration and 1960s social welfare programs, Anthony Abraham Jack on how elite institutions continue to fail first-generation college students, Mehrsa Baradaran on the racial wealth gap, Nicole Fleetwood on carceral art, and Joshua Bennett on the anti-Black bias implicit in how we talk about animals and the environment. Because the experiences of non-White people are integral to the history of racism and often bound up in the story of Black Americans, we have included writers who focus on the struggles of Native Americans, Latinos, and Asians as well. Racism in America is for all curious readers, teachers, and students who wish to discover for themselves the complex and rewarding intellectual work that has sustained our national conversation on race and will continue to guide us in future years.
In 1865, Gregor Mendel presented "Experiments in Plant-Hybridization," the results of his eight-year study of the principles of inheritance through experimentation with pea plants. Overlooked in its day, Mendel's work would later become the foundation of modern genetics. Did his pioneering research follow the rigors of real scientific inquiry, or was Mendel's data too good to be true—the product of doctored statistics? In Ending the Mendel-Fisher Controversy, leading experts present their conclusions on the legendary controversy surrounding the challenge to Mendel's findings by British statistician and biologist R. A. Fisher. In his 1936 paper "Has Mendel's Work Been Rediscovered?" Fisher suggested that Mendel's data could have been falsified in order to support his expectations. Fisher attributed the falsification to an unknown assistant of Mendel's. At the time, Fisher's criticism did not receive wide attention. Yet beginning in 1964, about the time of the centenary of Mendel's paper, scholars began to publicly discuss whether Fisher had successfully proven that Mendel's data was falsified. Since that time, numerous articles, letters, and comments have been published on the controversy.This self-contained volume includes everything the reader will need to know about the subject: an overview of the controversy; the original papers of Mendel and Fisher; four of the most important papers on the debate; and new updates, by the authors, of the latter four papers. Taken together, the authors contend, these voices argue for an end to the controversy-making this book the definitive last word on the subject.
What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.