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The basic objective of this book is to furnish the reader with the thorough understanding of mathematics topics included in the syllabus of B. Pharm. and Tech. (Biotechnology). The book explains: " Algebra, Determinant, Matrices " Measures of Central Values " Trigonometry " Analytical Plain Geometry " Calculus: Differential and Integral Calculus " Curve fitting, Solution of Cubic and Biquadratic Equations. Key Features " All fundamentals of the topics have been explained with a micro analysis. " Solved examples of different kinds of problems have been given to make the reader understand the various skills necessary to solve the problems. " Unsolved exercises of different kinds of problems have been given in a graded style
Calculations for Molecular Biology and Biotechnology: A Guide to Mathematics in the Laboratory, Second Edition, provides an introduction to the myriad of laboratory calculations used in molecular biology and biotechnology. The book begins by discussing the use of scientific notation and metric prefixes, which require the use of exponents and an understanding of significant digits. It explains the mathematics involved in making solutions; the characteristics of cell growth; the multiplicity of infection; and the quantification of nucleic acids. It includes chapters that deal with the mathematics involved in the use of radioisotopes in nucleic acid research; the synthesis of oligonucleotides; the polymerase chain reaction (PCR) method; and the development of recombinant DNA technology. Protein quantification and the assessment of protein activity are also discussed, along with the centrifugation method and applications of PCR in forensics and paternity testing. - Topics range from basic scientific notations to complex subjects like nucleic acid chemistry and recombinant DNA technology - Each chapter includes a brief explanation of the concept and covers necessary definitions, theory and rationale for each type of calculation - Recent applications of the procedures and computations in clinical, academic, industrial and basic research laboratories are cited throughout the text New to this Edition: - Updated and increased coverage of real time PCR and the mathematics used to measure gene expression - More sample problems in every chapter for readers to practice concepts
Pharmaceutical biotechnology is evolving as an increasingly vital tool in the field of life sciences by contributing to diagnostic medical tests, therapeutic drugs and also gene therapy for hereditary diseases. Pharmaceutical biotechnology tools such as recombinant proteins and transgenic organisms have revolutionised life sciences. This book aims to explain the basics and applications of pharmaceutical biotechnology to readers new to the subject. It is written and presented in a clear, easy-to-follow manner, and contains numerous figures and illustrations to explain the material. Consisting of 25 chapters divided into 5 units:- genetic engineering, plant biotechnology, animal biotechnology, microbiology and industrial biotechonology and nanobiotechnology – the book gives concise descriptions across all areas of biotechnology, brings the reader up to date with the latest findings, and also looks at what the future prospects have in store. Each chapter also offers suggested readings for further study. The three young authors have provided an excellent overview to the field of pharmaceutical biotechnology. The book can be read both as an introduction to the subject, and a synopsis of past, present and future findings. For this reason, it will be a valuable addition in any life science library.
This first ever coverage of the pharmacokinetic and pharmacodynamic characteristics of biopharmaceuticals meets the need for a comprehensive book in this field. It spans all topics from lead identification right up to final-stage clinical trials. Following an introduction to the role of PK and PD in the development of biotech drugs, the book goes on to cover the basics, including the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides, as well as viral and non-viral gene delivery vectors. The second section discusses such challenges and opportunities as pulmonary delivery of proteins and peptides, and the delivery of oligonucleotides. The final section considers the integration of PK and PD concepts into the biotech drug development plan, taking as case studies the preclinical and clinical drug development of tasidotin, as well as the examples of cetuximab and pegfilgrastim. The result is vital reading for all pharmaceutical researchers.
Books covering pharmaceutical sciences combined with statistics are not available in the market. To overcome this setback, this book is authored in a detailed and easy to understand manner incorporating the updated information containing the following features. Syllabus prescribed for B. Pharm & M. Pharm students is covered in detail The application of pharmaceutical statistics to research and clinical evaluation Prime importance is given to the creation of tables and graphs Data presentation, inferential tests such as parametric and nonparametric methods, regression and correlation factors are presented lucidly The importance of ANOVA in statistical designs used in pharmaceutical research Introduction of elementary concepts of the design and analysis of factorial designs Optimization techniques with suitable examples The important designs and their applications predominantly used in controlled clinical studies Application of statistics in quality control.
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