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Introduction. Centrak Nervous System Stimulants. Antidepressants and Antinxienty Agent (Anxiolytic). Antipsychotic Agents and Hallucinogens. General Anaestetics. Hypnotics and Sedatives. Skeletal Muscle Relaxants. Tranquilizing Agents. Anticonvulsant Drugs. Analgesics (Narcotcs). Anpyertic Analgesics. Nonsteroidal Anti- Inflammatory Agents. Adrenergic Agents. Adrenergic Blocking Agents. Cardiovascular Agents. Histamines & Antihistaminic Agents. antitussives & Expectorants. Coagulants and Anticoagulants
This Fourth Edition has been thoroughly revised and updated to take account of international developments in pharaceutical chemistry and to maintain the position of Practical Pharmaceutical Chemistry as the leading University textbook in the field of pharaceutical analysis and quality control. Part 2 deals with physical techniques of analysis for more advanced courses. It gives a broad coverage of the most widely used techniques in quantative chromatography. The treatmentof spectroscopy and radiopharmaceuticals has also been increased. Thre are additional chapters on the contribution and role of physical methods of analysis in the various stages of drug development; and a series of workshop-style exercises, illustrating the application of spectroscopic techniques in structural elucidation and verification of identity. Users of the two volumes will welcome the internationalisation of the text, with examples based on drugs and dosage forms that are widespread and in commun use in human medicine in Britain, continental Europe and North America. Additionally there is some reference to veterinary pharmaceuticals where they provide appropriate examples.
Syllabus(As per ER 1991)Antiseptics and Disinfectants-Proflavine*, Benzalkonium chloride, Cetrimide, Phenol, chloroxylenol, Formaldehyde solution, Hexachlophene, Nitrofurantoin. Sulphonamides- Sulphadiazine, Sulphaguanidine, Phthalylsulphathaizole, Succinylsulphathiazole, Sulphadimethoxine, Sulphamethoxypyridazine, Co-trimoxazole, sulfacetamide* Antileprotic Drugs-Clofazimine, Thiambutosine, Dapsone*, solapsone, Anti-tubercular Drugs- Isoniazid*, PAS*, Streptomycin, Rifampicin, Ethambutol*, Thiacetazone, Ethionamide, cycloserine, pyrazinamide*. Antimoebic and Anthelmintic Drugs- Emetine, Metronidazole, Halogenated hydroxyquinolines, Diloxanide furoate, Paromomycin, Piperazine*, Mebendazole, D.E.C.* Antibiotics- Benzyl penicillin*, Phenoxy methyl penicillin*, Benzathine penicillin, Ampicillin*, Cloxacillin, Carbencicillin, Gentamicin, Neomycin, Erythromycin, Tetracycline, Cephalexin, Cephaloridine, Cephalothin, Griseofulvin, Chloramphenicol. Antifungal agents- Udecylenic acid, Tolnaftate, Nystatin, Amphotericin, Hamycin. Antimalarial Drugs-Chloroquine*, Amodiaquine, Primaquine, Proguanil, Pyrimethamine*, Quinine, Trimethoprim. Tranquilizers-Chlorpromazine*, Prochlorperazine, Trifluoperazine, Thiothixene, Haloperiodol*, Triperiodol, Oxypertine, Chlordizepoxide, Diazepam*, Lorazepam, Meprobamate. Hypnotics- Phenobarbitone*, Butobarbitone, Cylobarbitone, Nitrazepam, Glutethimide*, Methyprylon, Paraldehyde, Triclofosodium. General Anaesthetics-Halothane*, Cyclopropane*, Diethyl ether*, Methohexital sodium, Thiopecal sodium, Trichloroethylene . Antidepressant Drugs- Amitriptyline, Nortryptyline, Imperamine*, Phepelzine, Tranylcypromine. Analeptics- Theophylline, Caffeine*, Coramine*, Dextro-amphetamine.Adrenergic drugs- Adrenaline*, Noradrenaline, Isoprenaline*, Phenylephrine, Salbutamol, Terbutaline, Ephedrne*, Pseudoephedrine. Adrenergic antagonist- Tolazoline, Propranolol*, Practolol. Cholinergic Drugs- Neostigmine*, Pyridostigmine, Pralidoxime, Pilocarpine, Physostigmine*. Cholinergic Antagonists- Atropine*, Hyoscine, Homatropine, Propantheline*, Benztropine, Tropicamide, Biperiden*. Diuretic Drugs- Furosemide*, Chlorothiazide, Hydrochlorothiazidc*, Benzthiazide, Urea*, Mannitol*, Ethacrynic Acid. Cardiovascular Drugs- Ethylnitrite*, Glyceryl trinitrate, Alpha methyldopa, Guanethidine, Clofibrate, Quinidine. Hypoglycaemic Agents- Insulin, Chlorpropamide*, Tolbutamide, Glibenclamide, Phenformin*, Metformin. Coagulants and Anti coagulants- Heparin, Thrombin, Menadione*, Bisphydroxy-coumarin, Warfarin sodium. Local Anaesthetics- Lignocaine*, Procaine*, Benzocaine, Histamine and anti-Histaminic Agents- Histamine, Diphenhydramine*, Promethazine, Cyproheptadine, Mepyramine*, Pheniramine, Chlorpheniramine*, Analgesics and Anti-pyretics- Morphine, Pethidine, Codeine, Mathadone, Aspirin*, Paracetamol, Analgin, Dextropropoxphene, Pentazocine. Non-steriodal anti-inflammatory agents- Indomethacin*, Phenylbutazone*, Oxyphenbutazone, Ibuprofen. Thyroxine and Antithyroids- Thyroxine*, Methimazole, Methyl thiouracil, Propylthiouracil. Diagnostic Agents- Lopanoic Acid, Propyliodone, Sulfobromopthalein-sodium, Indigotindisulfonate, Indigo Carmine, Evans blue, Congo Red, Fluorescein sodium. Anticonvulsants, cardiac glycosides, Antiarrhythmic, Antihypertensives&Vitamins.Steroidal Drugs- Betamethasone, Cortisone, Hydrocortisone, Prednisolone, Progesterone, Testosterone, Oestradiol, Nandrolone. Anti-Neoplastic Drugs- Actinomycin, Azathioprie, Busulphan, Chloramubucil, Cisplatin, Cyclophosphamide, Daunorubicin Hydrochoride, Fluorouracil, Mercaptopurine, Methotrexate, Mytomycin.
Dr Alagarsamy's Textbook of Medicinal Chemistry is a much-awaited masterpiece in its arena. Targeted mainly to B. Pharm. students, this book will also be useful for M. Pharm. as well as M. Sc. organic chemistry and pharmaceutical chemistry students. It aims at eliminating the inadequacies in teaching and learning of medicinal chemistry by providing enormous information on all the topics in medicinal chemistry of synthetic drugs. Salient Features Contains clear classification, synthetic schemes, mode of action, metabolism, assay, pharmacological uses with the dose and structure–activity relationship (SAR) of the following classes of drugs: Drugs acting on inflammation Drugs acting on respiratory system Drugs acting on digestive system Drugs acting on blood and blood-forming organs Drugs acting on endocrine system Contains a complete section on chemotherapy and the various classes of chemotherapeutic agents. Also includes recent topics like anti-HIV agents Contains brief introduction about the physiological and pathophysiological conditions of diseases and their treatment under each topic Provides well-illustrated synthetic schemes and alternative synthetic routes for majority of drugs that help in quick and enhanced understanding of the subject Covers the syllabi of majority of Indian universities
Introducing the book "Medicinal Chemistry - II" is something that fills me with an incredible amount of joy. The content of this book has been meticulously crafted to adhere to the curriculum for Bachelor of Pharmacy students that has been outlined by the Pharmacy Council of India. An effort has been made to investigate the topic using terminology that is as straightforward as possible in order to make it more simply digestible for pupils. The book has a number of illustrations, such as flowcharts and diagrams that make it simple for students to comprehend complex ideas. It is the author's honest desire that both students and academicians would take something helpful away from reading this book.
An introduction to pharmaceutical chemistry for undergraduate pharmacy, chemistry and medicinal chemistry students. Essentials of Pharmaceutical Chemistry is a chemistry introduction that covers all of the core material necessary to provide an understanding of the basic chemistry of drug molecules. Now a core text on many university courses, it contains numerous worked examples and problems